Immune System News and Research

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Risk of tick bite potentially leading to red meat allergy is higher than expected

Until now it has been believed that in order for a tick to trigger an allergic immune response to alpha-gal in humans, the tick would need to have recently fed on the alpha-gal-rich blood of a mammal.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

Neighborhood income, education associated with risk of disability progression in MS patients

Neighborhood income and education level is associated with risk of disability progression in patients with multiple sclerosis, suggests new research from the University of British Columbia.

23 Feb 2019

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

The composition of the microbiome - the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs - makes a decisive contribution to human health or disease.

23 Feb 2019

Akna protein plays a key role in the regulation of neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine.

22 Feb 2019

Reduced antibody adaptability may make the elderly more vulnerable to influenza

The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report February 19 in the journal Cell Host & Microbe.

21 Feb 2019

Scientists uncover new mechanisms regulating neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. Scientists at Helmholtz Zentrum München and Ludwig Maximilian University of Munich have discovered that the protein Akna plays a key role in this process.

21 Feb 2019

New sepsis test could save thousands of lives

Researchers have used a biosensor that can quickly identify biomarkers of sepsis and has the potential to save thousands of lives.

21 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumors in several mouse models.

20 Feb 2019

Elevated levels of key cellular process implicated in intestinal inflammation and IBD

Elevated levels of the key cellular process of apoptosis have been implicated in intestinal inflammation and inflammatory bowel disease in a new study from the Quadram Institute.

20 Feb 2019

New optimization method rapidly analyzes nanomedicines for cancer treatment

With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full potential, researchers need to optimize their various components.

20 Feb 2019

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

New screening method could catch organ rejection much earlier without a biopsy needle

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle.

20 Feb 2019

T-cells play key role in how the body fights follicular lymphoma

Healthy white blood cells, called "T-cells," play a crucial role in how the body fights follicular lymphoma. That's according to the results of a study led by Mayo Clinic hematologists Zhi Zhang Yang, M.D., and Stephen Ansell, M.D., Ph.D., that was published in Cell Reports.

20 Feb 2019

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system's ability to fight melanoma in mice.

20 Feb 2019

Researchers explain why T cells lose their protective ability in inflamed tissues

Regulatory T cells make sure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies against inflammatory autoimmune diseases such as multiple sclerosis.

20 Feb 2019

Study reveals how helper T cells support memory cells to function optimally

The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells', live on once infection is controlled in order to fight re-infection by the same virus. They are of great interest as the basis of T cell-based vaccination and immunotherapies.

20 Feb 2019

Study finds new link between food allergies and multiple sclerosis

Like many other medical conditions, the mechanism of multiple sclerosis remains an enigma--a puzzle composed of complex genetic and environmental factors. A key piece to this puzzle is the immune system, which is also responsible for regulating many other physiological (and pathological) phenomena--including allergies.

19 Feb 2019

Anti-cancer immunotherapy could be used to fight HIV

Researchers at the University of Montreal Hospital Research Centre have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy.

19 Feb 2019

Immune System News and Research

Risk of tick bite potentially leading to red meat allergy is higher than expected

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Neighborhood income, education associated with risk of disability progression in MS patients

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

Akna protein plays a key role in the regulation of neural stem cells

Reduced antibody adaptability may make the elderly more vulnerable to influenza

Scientists uncover new mechanisms regulating neural stem cells

New sepsis test could save thousands of lives

Johns Hopkins scientists find new compound that may prevent reperfusion injury

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Elevated levels of key cellular process implicated in intestinal inflammation and IBD

New optimization method rapidly analyzes nanomedicines for cancer treatment

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

New screening method could catch organ rejection much earlier without a biopsy needle

T-cells play key role in how the body fights follicular lymphoma

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers explain why T cells lose their protective ability in inflamed tissues

Study reveals how helper T cells support memory cells to function optimally

Study finds new link between food allergies and multiple sclerosis

Anti-cancer immunotherapy could be used to fight HIV

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