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Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers at University of California San Diego report that while Kawasaki disease (KD) occurs in clusters, the traits, and thus the triggers of the inflammatory disease vary among clusters. The findings are published in the September 2020 online issue of The Journal of Pediatrics.

30 Sep 2020

Gut bacteria may play a role in prostate cancer therapies

A new study from Lawson Health Research Institute and Western University illustrates how the gut microbiome interacts with an oral medication in prostate cancer patients, suggesting bacteria in the gut play a role in treatment outcomes.

30 Sep 2020

Study shows tofacitinib drug can repair permeability defects in the intestine

A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can repair permeability defects in the intestine.

30 Sep 2020

Study reveals unexpected mechanisms involved in working memory

Working memory: it's how you make a mental shopping list without forgetting the milk, or memorize a number just long enough to write it down.

29 Sep 2020

Australian scientists develop a nasal spray that could stop SARS-CoV-2 infection

The novel product, called INNA-051, is being developed by Ena Respiratory, and laboratory experiments have shown that it reduced viral replication by as much as 96 percent in the animal study. Spearheaded by Public Health England’s (PHE) Deputy Director, Professor Miles Carroll, the new study described the potential treatment and has been published in the open-source preprint server bioRxiv*.

29 Sep 2020

Self-collection of blood for COVID-19 antibody testing may be a reliable and easy alternative

Some evidence suggests that IgGs appear at 6-15 days after infection and may persist for months. However, large-scale testing over time is required to understand the immunological response to COVID-19 with greater accuracy. A recent pilot study published on the preprint server medRxiv in September 2020 reports the use of self-collected capillary blood for serology, with highly promising results.

29 Sep 2020

Qatar worker communities may have attained herd immunity against SARS-CoV-2

Now, a recent study published on the preprint server medRxiv* in September 2020 shows the achievement of herd immunity for SARS-CoV-2 infection by at least some expatriate worker communities in Qatar.

29 Sep 2020

EPFL scientists measure the molecular footprint of aging

EPFL scientists have measured the molecular footprint that aging leaves on various mouse and human tissues. Using the data, they have identified likely regulators of this central process.

29 Sep 2020

Unexplained repeated pregnancy loss may be linked to the olfactory system

The odors we give off are a sort of body language - one that may affect our relationships more than we realize.

29 Sep 2020

Vitamin D deficiency during early development can influence metabolic health

Using a zebrafish model, researchers from North Carolina State University have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation.

29 Sep 2020

Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome

The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins syndrome (PTHS).

29 Sep 2020

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body.

29 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Researchers develop a new substance that can disarm tumor-promoting proteins

The villain in this drama has a pretty name: Aurora - Latin for dawn. In the world of biochemistry, however, Aurora (more precisely: Aurora-A kinase) stands for a protein that causes extensive damage. There, it has been known for a long time that Aurora often causes cancer.

29 Sep 2020

Labconco's new glassware washer

Labconco® Laboratory Washers Introduce New Level of Versatility, Capability.

From Labconco 29 Sep 2020

PrimeStore® MTM novel viral transport media successfully evaluated by Public Health England for SARS-CoV-2 inactivation

EKF Diagnostics announces that the novel viral transport media PrimeStore® MTM has been successfully evaluated for effective SARS-CoV-2 inactivation.

From EKF Diagnostics 29 Sep 2020

Researchers develop unique diagnostic tool to detect dystonia from MRI scans

Researchers at Mass Eye and Ear have developed a unique diagnostic tool that can detect dystonia from MRI scans, the first technology of its kind to provide an objective diagnosis of the disorder.

29 Sep 2020

Observation offers a better understanding of how neurons communicate with each other

The dialogue between neurons is of critical importance for all nervous system activities, from breathing to sensing, thinking to running. Yet neuronal communication is so fast, and at such a small scale, that it is exceedingly difficult to explain precisely how it occurs.

29 Sep 2020

Fear of COVID-19 can increase risk of substance abuse

Long after a COVID-19 vaccination is developed and years after the coronavirus death toll is tallied, the impact on mental health will linger, continuing to inflict damage if not addressed, according to new research.

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020