Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Transplanted human brain cells in a mouse brain provide insight into neural circuit formation

The brain cortex, the outside layer of our brain often referred to as grey matter, is one of the most complex structures found in living organisms. It gives us the advanced cognitive abilities that distinguish us from other animals.

21 Nov 2019

Charcot-Marie-Tooth disease study unearths a new mechanism of neurodegeneration

Charcot-Marie-Tooth disease is an inherited neurodegenerative condition that affects 1 in 2500 individuals.

21 Nov 2019

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

Northwestern Medicine scientists have discovered a new phenomenon in the brain that could explain the development of early stages of neurodegeneration seen in diseases such as ALS, which affects voluntary muscle movement such as walking and talking.

18 Nov 2019

Study unravels how insulin interacts with its receptor

Since the discovery of insulin nearly 100 years ago, scientists have explored how it interacts with its receptor with the goal of improving the ability of therapeutic insulins to mimic the way insulin works in the body.

14 Nov 2019

Could improving the brain’s waste disposal system help prevent Parkinson’s and Alzheimer’s?

A new partnership between two leading medical research charities has launched today to explore how improving the brain’s waste disposal system could be the key to preventing Parkinson’s and Alzheimer’s disease.

8 Nov 2019

Newly identified gene variant may offer potential treatment for Alzheimer's disease

Defying the odds, an individual at high risk for early-onset Alzheimer's disease remained dementia-free for many years beyond what was anticipated.

4 Nov 2019

Researchers make major breakthrough in cell signalling

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signalling.

4 Nov 2019

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

An international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differentiation of neurons.

30 Oct 2019

NEOMED professor receives DOD grant to explore if exercise proves to be neuroprotective

Sheila Fleming, Ph.D., an assistant professor of pharmaceutical sciences at Northeast Ohio Medical University, was recently awarded a three-year, $954,566 grant by the U.S. Army Medical Research Acquisition Activity for the project titled, "Exercise Effects on Synuclein Aggregation, Neuroinflammation, and Neurodegeneration."

29 Oct 2019

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke and National Institute for Aging to establish CONNECT-TBI--a program spanning 12 institutions which will study traumatic brain injury and related neurodegenerative diseases.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

Long-term exposure to toxic chemicals in the environment impairs brain function in mice

Human-made toxic chemicals that linger indefinitely in the environment disrupt the performance of critical helper cells in the mouse brain, leading to impaired function over long-term exposures, say neuroscientists at Georgetown University Medical Center.

22 Oct 2019

Researchers analyze neurodegeneration linked to FXTAS by measuring motor behavior

The neurological disorder FXTAS stems from a genetic premutation seen in one of every 151 women and one of every 468 men, called the FMR1 premutation.

17 Oct 2019

Brain's neural activity plays a role in human aging, life span

The brain's neural activity-;long implicated in disorders ranging from dementia to epilepsy-;also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School.

16 Oct 2019

How dementia spreads: new study says it’s through neural networks

Scientists have found out a way to forecast the spread of brain atrophy, using prior research that shows how brain networks connect with each other to form a continuously linked pathway.

14 Oct 2019

Dementia spreads via synaptic connections between brain networks

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia, adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.

14 Oct 2019

Suppressing brain immune cells might prevent or delay the onset of dementia

Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible in brain scans and people start to become forgetful and confused.

10 Oct 2019

Neurodegeneration News and Research

Further Reading

Transplanted human brain cells in a mouse brain provide insight into neural circuit formation

Charcot-Marie-Tooth disease study unearths a new mechanism of neurodegeneration

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

Study unravels how insulin interacts with its receptor

Could improving the brain’s waste disposal system help prevent Parkinson’s and Alzheimer’s?

Newly identified gene variant may offer potential treatment for Alzheimer's disease

Researchers make major breakthrough in cell signalling

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

NEOMED professor receives DOD grant to explore if exercise proves to be neuroprotective

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Long-term exposure to toxic chemicals in the environment impairs brain function in mice

Researchers analyze neurodegeneration linked to FXTAS by measuring motor behavior

Brain's neural activity plays a role in human aging, life span

How dementia spreads: new study says it’s through neural networks

Dementia spreads via synaptic connections between brain networks

Suppressing brain immune cells might prevent or delay the onset of dementia

Study reveals link between alterations in RNA splicing and Alzheimer's disease

UVA researchers uncover key contributor to multiple sclerosis

Experts call for public health campaign aimed at promoting 'brain-healthy lifestyle'

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