Immune System News and Research

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Researchers manipulate T cells to improve transplant success

Researchers have manipulated T cells in a way that prevents the rejection of transplanted organs, without affecting the immune system’s ability to fight microbial infection.

15 Jan 2019

Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time.

14 Jan 2019

Gut microbiome may help prevent development of cow's milk allergy

New research suggests that the gut microbiome may help prevent the development of cow's milk allergy. Scientists at the University of Chicago found that gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions, while gut microbes transplanted from infants allergic to milk did not.

14 Jan 2019

DNA origami can accurately measure how antibodies interact with several antigens

Using DNA origami - DNA-based design of precise nanostructures - scientists at Karolinska Institutet in collaboration with researchers at University of Oslo, have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system.

14 Jan 2019

Scientists find link between colitis and colon cancer

Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer.

14 Jan 2019

Lupus Research Alliance announces research awards to accelerate development of new therapies

Can "borrowed" drugs for treating other diseases protect the skin in patients with lupus? Can researchers coax the body to weed out harmful immune cells that drive tissue destruction in lupus? Those are just two of the innovative approaches for lupus therapies recognized by the Lupus Research Alliance with the latest round of its Target Identification in Lupus grants.

11 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

Study finds specific function of HIV protein that slows viral spread in early stages of infection

A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral spread in the earliest stages of infection.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

In the January 7th edition of Communications Biology, researchers at InsideOutBio argue that an unusual form of DNA with a reverse twist may have helped thwart the invasion of the human genome by junk DNA.

11 Jan 2019

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population.

10 Jan 2019

Quanterix extends oncology footprint with accelerated launch of next gen SP-X platform and CorPlex validated 10-Plex

Quanterix announce launch of its Simoa SP-X Imaging and Detection System, 10-Plex Simoa CorPlex Cytokine Panel, and broad menu of additional multiplex panels.

From Quanterix 10 Jan 2019

Research provides clues for understanding and optimizing bone marrow transplants

Bone marrow transplants, which involve transplanting healthy blood stem cells, offer the best treatment for many types of cancers, blood disorders and immune diseases. Even though 22,000 of these procedures are performed each year in the US, much remains to be understood about how they work.

9 Jan 2019

Olympus and USC announce new partnership to advance cancer research

The University of Southern California and Olympus have announced their first-ever co-development partnership with the goal of advancing multiscale research into cancer prevention, diagnosis, and treatment through precision medicine.

From Evident Corporation - Life Sciences 9 Jan 2019

Drug combination has added benefit for patients with melanoma

The German Institute for Quality and Efficiency in Health Care investigated whether the drug combinations of dabrafenib plus trametinib and of encorafenib plus binimetinib have an added benefit in comparison with the appropriate comparator therapies for patients with melanoma.

9 Jan 2019

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Using a unique bioinformatics technique developed at the University of Alabama at Birmingham, UAB researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery.

9 Jan 2019

Study highlights efforts to address widespread PFAS contamination in drinking water

A new analysis shows variation in the way state and federal regulators manage PFAS contaminants in drinking water, with some states adopting guideline levels that are more health protective than the non-enforceable levels set by the U.S. Environmental Protection Agency.

9 Jan 2019

Dental flossing and other consumer behaviors contribute to elevated levels of PFAS in the body

A new study suggests certain types of consumer behaviors, including flossing with Oral-B Glide dental floss, contribute to elevated levels in the body of toxic PFAS chemicals. PFAS are water- and grease-proof substances that have been linked with numerous health problems.

8 Jan 2019

Scientists explore bacterial immunity to better understand infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death.

8 Jan 2019

New analytic method can precisely detect viral infections using immune responses

Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check but can become dangerous when the immune system is weakened or during pregnancy.

8 Jan 2019

Immune System News and Research

Researchers manipulate T cells to improve transplant success

Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Gut microbiome may help prevent development of cow's milk allergy

DNA origami can accurately measure how antibodies interact with several antigens

Scientists find link between colitis and colon cancer

Lupus Research Alliance announces research awards to accelerate development of new therapies

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Study finds specific function of HIV protein that slows viral spread in early stages of infection

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Quanterix extends oncology footprint with accelerated launch of next gen SP-X platform and CorPlex validated 10-Plex

Research provides clues for understanding and optimizing bone marrow transplants

Olympus and USC announce new partnership to advance cancer research

Drug combination has added benefit for patients with melanoma

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Study highlights efforts to address widespread PFAS contamination in drinking water

Dental flossing and other consumer behaviors contribute to elevated levels of PFAS in the body

Scientists explore bacterial immunity to better understand infectious disease

New analytic method can precisely detect viral infections using immune responses

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