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Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Placebo in addition to methadone shown to be feasible treatment for opioid use disorder

There were more than 100,000 reported deaths from opioid overdoses in 2021, according to the Centers for Disease Control and Prevention.

12 Apr 2023

COVID-19 pandemic caused significant variations in cancer reporting

New research from the American College of Surgeons (ACS) outlines significant ways that the COVID-19 pandemic destabilized usual patterns of cancer care as reported in the National Cancer Database (NCDB), one of the largest cancer registries in the world used by thousands of hospitals and centers around the country to inform and improve the quality of cancer care.

12 Apr 2023

Machine learning methods may be effective in screening patients for sleep disorder risk

A machine learning model can effectively predict a patient's risk for a sleep disorder using demographic and lifestyle data, physical exam results and laboratory values, according to a new study published this week in the open-access journal PLOS ONE by Samuel Y. Huang of Virginia Commonwealth University School of Medicine, and Alexander A. Huang of Northwestern Feinberg University School of Medicine, US.

12 Apr 2023

Dopamine may play key role in why exercise feels "easy" to some people and exhausting to others

Dopamine, a brain chemical long associated with pleasure, motivation and reward-seeking, also appears to play an important role in why exercise and other physical efforts feel "easy" to some people and exhausting to others, according to results of a study of people with Parkinson's disease led by Johns Hopkins Medicine researchers. Parkinson's disease is marked by a loss of dopamine-producing cells in the brain over time.

12 Apr 2023

New approach identifies significant molecular changes linked to pediatric bipolar disorder

It's extremely difficult to study the biological basis of psychiatric disorders, in part because researchers can't easily collect brain cells from living people to study in the laboratory. Now, University of Utah Health scientists have developed a way around that.

12 Apr 2023

Male alcohol consumption before conception causes facial growth defects in offspring

According to the U.S. Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects in their unborn child.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Investigators from Cedars-Sinai Cancer are collaborating on a streamlined clinical trial design in a study called Pragmatica-Lung.

12 Apr 2023

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

New technologies that can capture subtle changes in a patient's voice may help physicians diagnose cognitive impairment and Alzheimer's disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer's Association publication Diagnosis, Assessment & Disease Monitoring.

12 Apr 2023

Women with multiple tumors in one breast may be able to avoid a mastectomy

Patients who have multiple tumors in one breast may be able to avoid a mastectomy if the tumors can be removed while leaving enough breast tissue, according to research led by the Alliance in Clinical Trials in Oncology and Mayo Clinic Comprehensive Cancer Center.

12 Apr 2023

Researchers use a quick, portable process to produce promising virus-fighting protein

A multidisciplinary research team has produced a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak.

12 Apr 2023

Sedentary time may significantly increase heart size in adolescents

In adolescents, sedentary time may increase heart size three times more than moderate-to-vigorous physical activity, a paper published in the Scandinavian Journal of Medicine & Science in Sports concludes.

12 Apr 2023

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

The National Cancer Institute, part of the National Institutes of Health (NIH), has helped launch a phase 3 randomized clinical trial (NCT05633602) of a two-drug combination to treat patients with advanced non-small cell lung cancer (NSCLC).

12 Apr 2023

Positive age beliefs contribute to recovery from mild cognitive impairment

A Yale School of Public Health study has found that older persons with mild cognitive impairment (MCI), a common type of memory loss, were 30% more likely to regain normal cognition if they had taken in positive beliefs about aging from their culture, compared to those who had taken in negative beliefs.

12 Apr 2023

Medicine News and Research

Researchers discover important drug target for preventing blood cancer

Placebo in addition to methadone shown to be feasible treatment for opioid use disorder

COVID-19 pandemic caused significant variations in cancer reporting

Machine learning methods may be effective in screening patients for sleep disorder risk

Dopamine may play key role in why exercise feels "easy" to some people and exhausting to others

New approach identifies significant molecular changes linked to pediatric bipolar disorder

Male alcohol consumption before conception causes facial growth defects in offspring

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

Women with multiple tumors in one breast may be able to avoid a mastectomy

Researchers use a quick, portable process to produce promising virus-fighting protein

Sedentary time may significantly increase heart size in adolescents

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

Positive age beliefs contribute to recovery from mild cognitive impairment

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

New insights into how Omicron variants avoid destruction by "killer" T cells

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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