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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

UCLA biologists uncover how head injuries can lead to serious brain disorders

UCLA biologists have discovered how head injuries adversely affect individual cells and genes that can lead to serious brain disorders.

17 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Over 30 years ago, Marsha and Allen Barnett lost their sons to a puzzling childhood disease that relentlessly attacked their nervous systems and sapped their energy.

15 Nov 2018

Researchers develop new drug molecule that inhibits inflammation

A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action.

15 Nov 2018

Non-coding genetic variant plays key role in endothelial function and disease incidence

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.

15 Nov 2018

Luxia Scientific announces availability of its gut microbiome test in Luxembourg

Luxia Scientific, a French biotech dedicated to improving well-being and health for all through the analysis and understanding of the microbiome, announces the availability of its test “1test1” in Luxembourg. The test was launched in France beginning of October 2018.

15 Nov 2018

Researchers directly connect activities of genes with instinctive behavior in male cichlids

Call it instinct, but something compels some animals to behave in certain ways, perhaps programs in their genes. Researchers have directly connected activities of genes with instinctive behavior in little male fish that make patterns in the sand to attract their mates.

15 Nov 2018

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.

14 Nov 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

Study defines biomarker in response to treatment of castration-resistant prostate cancer

The most aggressive type of prostate cancer, castration-resistant prostate cancer, can be treated with two different therapies: taxanes or hormone treatment. Until this day there are no comparative studies between the two and the decision on which treatment to use is done empirically and based on the patient's preferences.

14 Nov 2018

New technology based on moths and magnets could help treat genetic diseases

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis.

14 Nov 2018

People with rare cancers can benefit from genomic profiling, shows research

New research has shown that many Australians with rare cancers can benefit from genomic profiling. The findings of the patient-driven trial are being presented today at the Clinical Oncology Society of Australia Annual Scientific Meeting and could result in dramatic changes to the way those with rare cancers are diagnosed and treated.

14 Nov 2018

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers have provided new insight on the mechanisms behind the development of clear cell Renal Cell Carcinoma (ccRCC), according to new findings published in eLife.

13 Nov 2018

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

According to new research, epigenetic changes found in the offspring exposed to maternal smoking during pregnancy or in current smokers are linked to smoking-related diseases in adulthood.

13 Nov 2018

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy, which is also commonly observed in Alzheimer disease.

13 Nov 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

Researchers discover possible path forward in preventing cancers tied to two viruses

Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis--more commonly known as mono or the "kissing disease"--that infects millions of people around the globe each year.

12 Nov 2018

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Failed DNA repair triggers chromosomal chaos in cancer cells

Researchers have established the trigger for catastrophic events that occur within the chromosomes of cancer cells and lead to cancer cell death.

12 Nov 2018

DNA News and Research

Further Reading

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

UCLA biologists uncover how head injuries can lead to serious brain disorders

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Researchers develop new drug molecule that inhibits inflammation

Non-coding genetic variant plays key role in endothelial function and disease incidence

Luxia Scientific announces availability of its gut microbiome test in Luxembourg

Researchers directly connect activities of genes with instinctive behavior in male cichlids

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

Speed and error rate of DNA synthesis influenced by DNA structure

Study defines biomarker in response to treatment of castration-resistant prostate cancer

New technology based on moths and magnets could help treat genetic diseases

People with rare cancers can benefit from genomic profiling, shows research

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

First bifacial molecule can invade double-stranded DNA or RNA

Researchers discover possible path forward in preventing cancers tied to two viruses

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Failed DNA repair triggers chromosomal chaos in cancer cells

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