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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Common bacteria that cause foodborne diseases found to be resistant to antibiotics

Brazil's Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and 167 dying from the diseases in question.

9 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life -- including humans.

9 Nov 2018

UCI researchers accelerate and simplify directed evolution bioengineering technique

In a process known as directed evolution, scientists reengineer biomolecules to find ones that perform beneficial new functions. The field is revolutionizing drug development, chemical engineering and other applications, but to realize its promise involves painstaking and time-consuming laboratory work.

9 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

Cells retain memory of chemical signals to which they are exposed

We all start out as a clump of identical cells. As these cells divide and multiply, they gradually take on distinct identities, acquiring the traits necessary to form, for instance, muscle tissue, bone, or nerves. A recent study from Rockefeller scientists offers new insight into how these cellular identities are cultivated over the course of development.

9 Nov 2018

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes.

8 Nov 2018

Changing Perspectives of the Triggers of Cell Division

Cell division is integral to understanding development, growth and disease states such as cancer. It has long been known that for replication, a complete new set of DNA and the formation of a septum, dividing the two cells, are necessary. New research changes perspectives of how these two processes influence the timing of cell division.

8 Nov 2018

Scientist wins award for research in the field of commensal microbiota

The winner of the Johanna Duermueller-Bol DBMR Research Award 2018 is Dr. Stephanie Ganal-Vonarburg. As a Senior Scientist, she conducts research in the Gastroenterology / Mucosal Immunology Research Laboratory at Bern University Hospital and at the Department for BioMedical Research at the University of Bern.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off."

8 Nov 2018

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.

8 Nov 2018

New open source decision support tool could help clinicians chose chemotherapy drugs

The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?

8 Nov 2018

Study elucidates genetic causes of severe cardiomyopathies in children

Cardiac muscle degeneration (cardiomyopathy) is the most common cause of severe cardiac dysfunction and life-threatening cardiac arrhythmias in children. These severe disorders often lead to consideration of heart transplant. However, their actual cause - the genetic basis - has been poorly characterized.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine.

7 Nov 2018

Experts study antibiotic resistance in recycled water

Bacteria that become resistant to antibiotics lead to an estimated 23,000 deaths and 2 million illnesses per year in the U.S. The Centers for Disease Control is launching an expansive effort to study various facets of the growing threat by funding researchers across the nation, including two prominent water experts at Virginia Tech.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

DNA News and Research

Further Reading

Common bacteria that cause foodborne diseases found to be resistant to antibiotics

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

UCI researchers accelerate and simplify directed evolution bioengineering technique

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

Cells retain memory of chemical signals to which they are exposed

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Changing Perspectives of the Triggers of Cell Division

Scientist wins award for research in the field of commensal microbiota

Oral antibiotic shows promise to cure uncomplicated gonorrhea

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

New open source decision support tool could help clinicians chose chemotherapy drugs

Study elucidates genetic causes of severe cardiomyopathies in children

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Experts study antibiotic resistance in recycled water

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Scientists discover new details about UHRF1 protein

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