Immune System News and Research

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Scientists support original theory about pancreas regeneration

A contentious debate among diabetes researchers has surrounded the regeneration of pancreatic insulin-producing cells: not if these cells regenerate, but rather how.

5 Dec 2018

Montana State-led research project wins $10 million grant to prevent bat-borne diseases

In an effort to prevent some of the world's most lethal diseases, an international research team spanning five continents and led by Montana State University will study bats in Australia, Bangladesh, Madagascar and Ghana.

5 Dec 2018

New approach turns B cells into factories that secrete sacs containing microRNAs

Cancer immunotherapy -- efforts to better arm a patient's own immune system to attack tumors -- has shown great potential for treating some cancers. Yet immunotherapy doesn't work for everyone, and some types of treatment can cause serious side effects.

5 Dec 2018

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

Physician-scientists from Children's Hospital of Philadelphia presented updated efficacy and safety data on Kymriah--the first-ever U.S. Food and Drug Administration approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers at the 60th American Society of Hematology annual meeting, as well as first-of-its-kind research on overcoming CAR T-cell resistance.

5 Dec 2018

Spaceflight does not compromise major part of the immune system, shows research

With a new crew arriving at the International Space Station, astronauts will be relieved to know that they won't have to worry about a major aspect of their immune system being compromised.

5 Dec 2018

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Researchers at the University of Maryland School of Medicine's Maryland Psychiatric Center and Institute for Genome Sciences, along with researchers at the University of Maryland School of Pharmacy, have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia.

5 Dec 2018

Sema4, Mount Sinai, Sanofi announce launch of new collaborative asthma study

Sema4, a patient-centered predictive health company, and the Mount Sinai Health System today announced the launch of a five-year collaborative study with Sanofi designed to provide new insights into the biological mechanisms and other factors implicated in asthma.

4 Dec 2018

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

In certain forms of cancer, connective tissue forms around and within the tumor. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumor in different ways.

4 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Early gut bacterial colonization may reduce risk of developing eczema

Strains of a bacterium commonly found in skin infections may help to protect against eczema, according to new research in the British Journal of Dermatology.

4 Dec 2018

Clearer diagnosis of polio-like illness in young children

Johns Hopkins researchers have analyzed patient data from 45 cases of what they thought was acute flaccid myelitis, the polio-like outbreak occurring in U.S. children, and realized that only 75 percent of diagnosed cases were AFM.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

A new article published today in The Lancet Oncology shows 39 percent of large B cell lymphoma patients treated with the chimeric antigen receptor T-cell therapy Yescarta remained in remission more than two years following therapy, and more than half of the patients treated remain alive.

4 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Transmission of gut bacteria from mother to baby is impacted in cesarean-born children

Together with colleagues from Sweden and Luxembourg, scientists from the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have observed that, during a natural vaginal birth, specific bacteria from the mother's gut are passed on to the baby and stimulate the baby's immune responses.

30 Nov 2018

Researchers reveal how some cancers trick healthy cells into protecting tumors

Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so aggressive that outcome is poor, even after early diagnosis and chemotherapy.

30 Nov 2018

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Adoptive cell transfer is a promising cancer immunotherapy that involves isolating T cells from cancer patients that are capable of targeting their tumor, selecting the more active T cells and expanding those in the lab, and then transfusing them back into patients.

30 Nov 2018

Study points toward new strategies for managing organ transplantation

The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

30 Nov 2018

Immune System News and Research

Scientists support original theory about pancreas regeneration

Montana State-led research project wins $10 million grant to prevent bat-borne diseases

New approach turns B cells into factories that secrete sacs containing microRNAs

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

Spaceflight does not compromise major part of the immune system, shows research

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Sema4, Mount Sinai, Sanofi announce launch of new collaborative asthma study

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

Customizing Genetically Engineered Models for Specific Research Applications

Early gut bacterial colonization may reduce risk of developing eczema

Clearer diagnosis of polio-like illness in young children

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

International study increases group of lung cancer patients who may benefit from immunotherapy

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Using nanocarrier-delivered microRNA to target sepsis

Transmission of gut bacteria from mother to baby is impacted in cesarean-born children

Researchers reveal how some cancers trick healthy cells into protecting tumors

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Study points toward new strategies for managing organ transplantation

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