Lungs News and Research

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Eli Lilly presents early-stage data from several targeted cancer therapies at AACR 2014

Eli Lilly and Company will present early-stage data from several targeted cancer therapies – including bemaciclib "beh meh sye' klib" (LY2835219), its oral, cell-cycle inhibitor of CDK4/6 – that make up its diverse clinical oncology pipeline during the American Association for Cancer Research (AACR) Annual Meeting 2014 held in San Diego, Calif. from April 5 – 9.

7 Apr 2014

Women who had radiotherapy for breast cancer may have increased risk of lung tumour

Women who have radiotherapy for breast cancer have a small but significantly increased risk of subsequently developing a primary lung tumour, and now research has shown that this risk increases with the amount of radiation absorbed by the tissue.

7 Apr 2014

Merck KGaA initiates Phase 3 START2 study of MUC1 antigen-specific cancer immunotherapy tecemotide

Oncothyreon Inc. today announced that Merck KGaA, Darmstadt, Germany, has initiated the international Phase 3 START2 study, which is designed to assess the efficacy and safety of the investigational MUC1 antigen-specific cancer immunotherapy tecemotide (also known as L-BLP25) in patients with unresectable, locally advanced Stage III non-small cell lung cancer (NSCLC).

7 Apr 2014

Research provides new approach to developing better treatment options for scleroderma

Scleroderma is a rare and often fatal disease, causing the thickening of tissue, that currently lacks a cure and any effective treatments. A group of researchers, including a Michigan State University professor, is looking to change that.

7 Apr 2014

Blood sample could diagnose many types of solid cancers

A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive.

7 Apr 2014

Researchers examine role of antioxidants play in blocking harmful effects of omega 6 fatty acid

Given omega 6 fatty acid's reputation for promoting cancer - at least in animal studies - researchers are examining the role that antioxidants play in blocking the harmful effects of this culprit, found in many cooking oils.

7 Apr 2014

A novel device for inhalation drug delivery

Inhalation is an increasingly important route for non-invasive drug delivery for both systemic and local applications. Control of particle size and output plays a critical role in the efficient and effective delivery of oft en expensive medications to the lung.

4 Apr 2014

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Novartis announced today that early stage data on 19 investigational compounds in its oncology pipeline will be presented at the annual meeting of the American Association of Cancer Research, April 5-9, 2014 in San Diego, CA.

4 Apr 2014

CDC study finds dramatic increase in e-cigarette-related calls to poison centers

E-cigarettes, and liquid refill containers featuring bright colors, sweet-smelling flavors and dangerous doses of nicotine, are generating rising numbers of emergency calls to poison control centers around the nation, according to a study published today by the U.S. Centers for Disease Control and Prevention (CDC).

4 Apr 2014

Researchers examine risks and benefits of E-cigarettes

Some believe e-cigarettes are less harmful than smoking tobacco since e-cig vapor doesn't contain the chemicals found in tobacco smoke.

3 Apr 2014

New "3D" method could reduce the need for animal testing

To determine whether new medicines are safe and effective for humans, researchers must first test them in animals, which is costly and time-consuming, as well as ethically challenging.

3 Apr 2014

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Young adults who run or participate in other cardio fitness activities may preserve their memory and thinking skills in middle age, according to a new study published in the April 2, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as ages 43 to 55.

3 Apr 2014

BronchoGen genomic test meets primary endpoint in AEGIS-2 clinical trial

Allegro Diagnostics Corp. today announced that the AEGIS-2 clinical trial has met its primary endpoint, demonstrating that the BronchoGen genomic test improves the accuracy of lung cancer diagnosis when used in combination with bronchoscopy.

3 Apr 2014

Patients who stay longer in ICU have substantial physical impairments 2 years later

Patients have substantial physical impairments even two years after being discharged from the hospital after a stay in an intensive care unit (ICU), new Johns Hopkins research suggests.

3 Apr 2014

Scientists identify new biomarker linked to non-small cell lung cancer, head and neck cancers

A team led by a scientist from the Florida campus of The Scripps Research Institute has identified a new biomarker linked to better outcomes of patients with head and neck cancers and non-small cell lung cancer. The work could help scientists develop new diagnostics and therapies and help physicians determine the best long-term treatments for patients with these cancers.

3 Apr 2014

Expert in gene therapy joins The Children's Hospital of Philadelphia

Beverly L. Davidson, Ph.D., a nationally prominent expert in gene therapy, is joining The Children's Hospital of Philadelphia (CHOP) today.

2 Apr 2014

Uric acid in urine generates potentially hazardous in swimming pools by interacting with chlorine

A new study shows how uric acid in urine generates potentially hazardous "volatile disinfection byproducts" in swimming pools by interacting with chlorine, and researchers are advising swimmers to observe "improved hygiene habits.

2 Apr 2014

Solid-dominant lung cancer histology no barrier to segmentectomy

Complete resection with segmentectomy is as effective as lobectomy for patients with solid-dominant clinical stage IA lung adenocarcinoma, Japanese study findings suggest.

1 Apr 2014

Neuropeptide receptors could provide treatment target for chemoresistant SCLC

The discovery of a novel broad spectrum neuropeptide antagonist, peptide–1, which is related to the substance P analogue SP-G, could help develop treatments targeted at chemoresistant small-cell lung cancer, indicate study results.

1 Apr 2014

Study of non-surgically implanted replacement pulmonary valve shows strong results

The first post-FDA approval study of a non-surgically implanted replacement pulmonary valve showed strong short- and mid-term results for the device in patients with certain congenital heart defects, according to research presented by a U-M pediatric interventional cardiologist at the American College of Cardiology's 63rd Annual Scientific Session Sunday.

1 Apr 2014

Lungs News and Research

Eli Lilly presents early-stage data from several targeted cancer therapies at AACR 2014

Women who had radiotherapy for breast cancer may have increased risk of lung tumour

Merck KGaA initiates Phase 3 START2 study of MUC1 antigen-specific cancer immunotherapy tecemotide

Research provides new approach to developing better treatment options for scleroderma

Blood sample could diagnose many types of solid cancers

Researchers examine role of antioxidants play in blocking harmful effects of omega 6 fatty acid

A novel device for inhalation drug delivery

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

CDC study finds dramatic increase in e-cigarette-related calls to poison centers

Researchers examine risks and benefits of E-cigarettes

New "3D" method could reduce the need for animal testing

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

BronchoGen genomic test meets primary endpoint in AEGIS-2 clinical trial

Patients who stay longer in ICU have substantial physical impairments 2 years later

Scientists identify new biomarker linked to non-small cell lung cancer, head and neck cancers

Expert in gene therapy joins The Children's Hospital of Philadelphia

Uric acid in urine generates potentially hazardous in swimming pools by interacting with chlorine

Solid-dominant lung cancer histology no barrier to segmentectomy

Neuropeptide receptors could provide treatment target for chemoresistant SCLC

Study of non-surgically implanted replacement pulmonary valve shows strong results

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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