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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Immunotherapy with nivolumab and ipilimumab may improve survival in patients with MSI-high metastatic colorectal cancers

Immunotherapy with nivolumab and low-dose ipilimumab could become a new first line treatment in patients with some metastatic colorectal cancers following late-breaking results from the CheckMate-142 trial reported at the ESMO 2018 Congress in Munich.

22 Oct 2018

Researchers produce artificial antibody capable of blocking prions in the laboratory

Prion diseases affect the brain, causing neurodegenerative problems that always lead to death. They attracted attention in the late 1990s due to the "Mad Cow" scare.

22 Oct 2018

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients

Epigenetic therapy with histone deacetylase inhibitors is worth pursuing in hormone receptor positive advanced breast cancer, suggests a phase III trial reported today at the ESMO 2018 Congress in Munich.

22 Oct 2018

Texas A&M and UTA establish Texas Genomics Core Alliance

Texas A&M University and The University of Texas at Arlington have established The Texas Genomics Core Alliance to increase access to and decrease costs of cutting-edge, high-throughput genomics sequencing technologies.

22 Oct 2018

Could we prevent Alzheimer's disease by treating herpes?

An exciting new paper suggests that over half of all cases of Alzheimer’s disease could be traced back to herpes simplex virus 1, which causes cold sores.

19 Oct 2018

Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions.

19 Oct 2018

Newly developed synthetic DNA molecule may one day be used as 'vaccine' for prostate cancer

Researchers from City of Hope, a world-renowned comprehensive cancer center and independent biomedical research institution, have developed a synthetic DNA molecule that is programmed to jump-start the immune system to eradicate genetically distinct types of prostate cancer.

19 Oct 2018

Duke researchers find way to detect blood doping in athletes

A Duke University research team has found a way to help sporting officials detect whether an athlete's blood has been doped by an infusion of their own stored blood.

19 Oct 2018

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

19 Oct 2018

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3D genome architecture have now revealed crucial molecular aspects of this strategy.

19 Oct 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

A new approach identified to control Zika virus, dengue fever

Mosquitoes are the world's deadliest animals, killing thousands of people and causing millions of illnesses each year.

19 Oct 2018

Father’s exposure to nicotine may cause cognitive deficits in descendants

A father’s exposure to nicotine may cause cognitive deficits in his children and even grandchildren, according to a study in mice publishing on October 16 in the open-access journal PLOS Biology by Pradeep Bhide of Florida State University in Tallahassee and colleagues.

19 Oct 2018

DNA News and Research

Further Reading

Immunotherapy with nivolumab and ipilimumab may improve survival in patients with MSI-high metastatic colorectal cancers

Researchers produce artificial antibody capable of blocking prions in the laboratory

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients

Texas A&M and UTA establish Texas Genomics Core Alliance

Could we prevent Alzheimer's disease by treating herpes?

Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Newly developed synthetic DNA molecule may one day be used as 'vaccine' for prostate cancer

Duke researchers find way to detect blood doping in athletes

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

A new approach identified to control Zika virus, dengue fever

Father’s exposure to nicotine may cause cognitive deficits in descendants

New DNA vaccine strategy protects mice against lethal challenge by multiple H3N2 viruses

Genetically modifying zebrafish provides numerous, highly accurate disease models

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

Loss of tumor protein p53 helps cancer cells grow in hostile environment

Researchers demonstrate epigenetic memory transmission via sperm

Beckman Coulter Life Sciences announces new research-focused website

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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