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Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

Bloomberg Philanthropies introduces multi-faceted $50M reproductive health program for women

Bloomberg Philanthropies today announced the launch of a multi-faceted $50 million reproductive health program to prevent maternal deaths and help more women freely and safely make decisions about when to have children.

27 Mar 2014

Study: Depression treatments reduce mortality in patients with cardiovascular disease

Can treating depression in patients with heart failure help them live longer? That's one of the questions that University of Pittsburgh researchers hope to answer with a new five-year, $7.3 million grant from the National Heart, Lung, and Blood Institute, part of the National Institutes of Health (NIH).

27 Mar 2014

PET eliminates approximately 50% of unnecessary surgeries in lung cancer patients

New quantitative data suggests that 30 percent of the surgeries performed for non-small cell lung cancer patients in a community-wide clinical study were deemed unnecessary.

27 Mar 2014

New era of lung cancer therapy close to dawning

A new era of lung cancer therapy is close to dawning, using drugs that can prevent tumour cells from evading the immune system, experts have said at the 4th European Lung Cancer Congress.

27 Mar 2014

Vancouver-led research initiative awarded $1.5M grant to prevent deaths of moms and babies

A Vancouver-led research initiative to prevent deaths of moms and babies got a boost recently with a new $1.5-million grant from the Bill & Melinda Gates Foundation. The grant will expand efforts to improve diagnosis and care for pregnant women with pre-eclampsia.

27 Mar 2014

SLU researchers receive $1.4M grant to study alpha-1 antitrypsin deficiency in adults

Researchers at Saint Louis University will study alpha-1 antitrypsin deficiency in adults, an inherited disease that can cause liver damage, to answer various questions that could lead to effective methods of treatment.

27 Mar 2014

Higher exposure to TRAP increases odds of readmission to hospital for asthma

Higher exposure to traffic-related air pollution (TRAP) dramatically increases the odds of readmission to the hospital for asthma - but only for white children, according to a new Cincinnati Children's Hospital Medical Center study.

27 Mar 2014

Insmed reports results from ARIKAYCE phase 2 trial for treatment resistant NTM lung infections

Insmed Incorporated today reported results from the Company's phase 2 clinical trial of ARIKAYCETM, or liposomal amikacin for inhalation, for the treatment of patients with treatment resistant nontuberculous mycobacterial (NTM) lung infections.

26 Mar 2014

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

Concordia Healthcare Corp. announced today that its subsidiary Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, was granted U.S. Food and Drug Administration premarket supplemental approval (PMA) for its Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber.

26 Mar 2014

EKF Molecular to exhibit PointMan DNA-enrichment technology at AACR 2014

EKF Diagnostics, the global in vitro diagnostics business, will be present on Booth #438 at AACR 2014, 5-9th April, San Diego.

From EKF Diagnostics 26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Peach extract prevents breast cancer metastasis in mice

Lab tests at Texas A&M AgriLife Research have shown that treatments with peach extract inhibit breast cancer metastasis in mice.

26 Mar 2014

BIND Therapeutics reports revenue of $2.1 million for fourth quarter 2013

BIND Therapeutics, Inc., a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called AccurinsTM, today reported financial results for the fourth quarter and year-ended December 31, 2013.

25 Mar 2014

Researchers receive grants to advance work in prevention of premature birth

Researchers at UT Southwestern Medical Center received grants totaling $600,000 from the March of Dimes Foundation to advance their work in the prevention of premature birth, which affects about one out of nine babies born annually in the U.S. and is the leading cause of newborn death.

25 Mar 2014

ISTH declares Oct.13 as World Thrombosis Day

Bringing together nations and local communities to tackle thrombosis, the quiet, underlying disorder that is the common mechanism of the world's three top cardiovascular killers – heart attack, stroke and venous thromboembolism (VTE) – the International Society on Thrombosis and Haemostasis (ISTH) today announced that October 13 will be designated World Thrombosis Day, with the inaugural event to be held this year.

25 Mar 2014

WHO report confirms air pollution as world's largest single environmental health risk

In new estimates released today, WHO reports that in 2012 around 7 million people died - one in eight of total global deaths - as a result of air pollution exposure. This finding more than doubles previous estimates and confirms that air pollution is now the world's largest single environmental health risk. Reducing air pollution could save millions of lives.

25 Mar 2014

New technology gives tool to examine membrane proteins in natural environment of human cell

Scientists have a better way to study human proteins - large molecules that are part of every cell in the body - thanks to a new technology developed by University of Toronto researchers.

25 Mar 2014

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

A University of Cincinnati (UC) trauma and critical care researcher has received a National Institutes of Health grant to better understand how "microparticles" in stored blood can contribute to inflammation and injury after resuscitation from traumatic injury.

25 Mar 2014

Common cholesterol-lowering drugs provide relief to patients suffering from chronic lung disease

Common cholesterol-lowering drugs could provide relief to patients suffering from a chronic lung disease, a study has shown.

25 Mar 2014

Lungs News and Research

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Bloomberg Philanthropies introduces multi-faceted $50M reproductive health program for women

Study: Depression treatments reduce mortality in patients with cardiovascular disease

PET eliminates approximately 50% of unnecessary surgeries in lung cancer patients

New era of lung cancer therapy close to dawning

Vancouver-led research initiative awarded $1.5M grant to prevent deaths of moms and babies

SLU researchers receive $1.4M grant to study alpha-1 antitrypsin deficiency in adults

Higher exposure to TRAP increases odds of readmission to hospital for asthma

Insmed reports results from ARIKAYCE phase 2 trial for treatment resistant NTM lung infections

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

EKF Molecular to exhibit PointMan DNA-enrichment technology at AACR 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Peach extract prevents breast cancer metastasis in mice

BIND Therapeutics reports revenue of $2.1 million for fourth quarter 2013

Researchers receive grants to advance work in prevention of premature birth

ISTH declares Oct.13 as World Thrombosis Day

WHO report confirms air pollution as world's largest single environmental health risk

New technology gives tool to examine membrane proteins in natural environment of human cell

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

Common cholesterol-lowering drugs provide relief to patients suffering from chronic lung disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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