Adenosine Triphosphate (ATP) News and Research

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Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

Study finds slime and biofilm hidden in hospital sinks, faucets

Hand hygiene is a critical component of infection prevention in hospitals, but the unintended consequences include water splashing out of a sink to spread contaminants from dirty faucets according to new research presented last week in Philadelphia at the 46th Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

27 Jun 2019

Researchers engineer new molecules to help stop lung cancer

University of Texas at Dallas scientists have demonstrated that the growth rate of the majority of lung cancer cells relates directly to the availability of a crucial oxygen-metabolizing molecule.

24 Apr 2019

Promega offers new Water-Glo System for highly sensitive, rapid water quality testing

Water-Glo System, offers sensitive and flexible measurement to monitor microbial contamination with bioluminescent technology to measure adenosine triphosphate.

From Promega Corporation 13 Mar 2019

Lactate activates multiple genes that modulate neuronal activity

A genome-wide study led by Dean Pierre Magistretti sheds light on the mechanisms through which lactate regulates long-term memory formation and neuroprotection.

12 Feb 2019

Failure of critical cellular energy sensor responsible for CKD progression, study finds

Chronic kidney disease, an affliction characterized by progressive loss of kidney function, affects millions of people worldwide and is associated with multi-organ damage, cardiovascular disease, and muscle wasting.

7 Dec 2018

Metabolic dysfunction drives chronic illness

Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common cold to heart and asthma attacks.

7 Sep 2018

UD researcher investigates role of new compound in fighting age-related diseases

A University of Delaware researcher is investigating a novel compound's role in combating age-related chronic diseases like mild cognitive disorder and dementia.

3 Apr 2018

Scientists develop new technique to 'turn off' multi-drug resistance capabilities in cancer cells

The ability for cancer cells to develop resistance to chemotherapy drugs - known as multi-drug resistance - remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to "turn off" their resistance capabilities.

8 Feb 2018

Star-shaped brain cells may help control rhythm of breathing, NIH study suggests

Traditionally, scientists thought that star-shaped brain cells called astrocytes were steady, quiet supporters of their talkative, wire-like neighbors, called neurons. Now, an NIH study suggests that astrocytes may also have their say.

8 Feb 2018

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Hundreds of thousands of patients from newborns to the elderly are forced to grapple with the devastation of brain injury each year, and unlike many diseases where certain demographics are protected, brain injury can happen to anyone, anytime and anywhere.

4 Dec 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Zinc-binding plays key role in sensing and regulation of brain’s pH levels

Researchers in Oslo, Norway, have discovered that Zinc-binding plays an important role in the sensing and regulation of pH in the human brain. The findings come as one of the first studies that directly link Zinc-binding with bicarbonate transporters.

17 Oct 2017

Researchers harness lipid nanodiscs to produce hydrogen fuel

A U.S.-based team of researchers featuring MIPT scientists has assembled a nanoscale biological structure capable of producing hydrogen from water using light.

6 Sep 2017

Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

Sterilization and cleaning methods leave residual contamination on ureteroscopes

The techniques used to clean and sterilize flexible ureteroscopes leave behind contamination including debris, residue, and bacteria, according to a new study being presented at the 44th Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

14 Jun 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11.

11 May 2017