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Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Targeting metabolic pathways to combat Epstein-Barr virus infections

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers.

24 May 2024

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

The treatment landscape for multiple myeloma, the second most common blood cancer, is shifting rapidly, with newly diagnosed patients increasingly being treated with a four-part drug combination that includes a new immunotherapy agent.

24 May 2024

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.

24 May 2024

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.

24 May 2024

Phase 1 trial for EBC-129 progresses into dose expansion

The Experimental Drug Development Centre (EDDC), Singapore's national platform for drug discovery and development, is pleased to announce that the Phase 1 trial for EBC-129 has progressed into dose expansion.

24 May 2024

Soft X-ray microscope captures living mammalian cells

Researchers have developed a new technique to view living mammalian cells.

24 May 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

The case of the armadillo: Is it spreading leprosy in Florida?

In an open-air barn at the edge of the University of Florida, veterinarian Juan Campos Krauer examines a dead armadillo's footpads and ears for signs of infection.

24 May 2024

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

23 May 2024

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development.

23 May 2024

Newly discovered neuron type guides retinal blood vessel formation

Scientists have known for years that a lattice of blood vessels nourishes cells in the retina that allow us to see – but it's been a mystery how the intricate structure is created.

23 May 2024

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

A new treatment approach using an older drug may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, according to a study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and colleagues.

23 May 2024

UCLA research connects genetic risk and brain changes in autism

A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.

23 May 2024

New AI model sets benchmark in digital pathology with superior cancer diagnostics

Researchers developed Prov-GigaPath, a whole-slide pathology foundation model using a novel vision transformer architecture. The model demonstrates superior performance in mutation prediction, cancer subtyping, and vision-language tasks. It leverages large-scale real-world data from over 30,000 patients to enhance clinical diagnostics.

23 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Study sheds light on intricate differences in the brains of people with PTSD and depression

Stress-related disorders like post-traumatic stress disorder and clinical depression are complex conditions influenced by both genetics and our environment.

23 May 2024

Novel catalog of gene-isoform variation unveiled in the developing human brain

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

23 May 2024

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

In a study published in Cell Host & Microbe, a research team led by Prof. PAN Wen from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, in collaboration with research teams led by Prof. ZHU Shu and Prof. SONG Xinyang, demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis.

23 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system -; a therapy that has its own serious risks.

23 May 2024

Cell News and Research

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Targeting metabolic pathways to combat Epstein-Barr virus infections

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

Phase 1 trial for EBC-129 progresses into dose expansion

Soft X-ray microscope captures living mammalian cells

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

The case of the armadillo: Is it spreading leprosy in Florida?

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Newly discovered neuron type guides retinal blood vessel formation

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

UCLA research connects genetic risk and brain changes in autism

New AI model sets benchmark in digital pathology with superior cancer diagnostics

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Study sheds light on intricate differences in the brains of people with PTSD and depression

Novel catalog of gene-isoform variation unveiled in the developing human brain

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

New genetic discoveries offer hope for targeted lupus therapies

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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