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The decision-making process for the launch of trials for COVID-19 repurposed antivirals

Researchers reviewed the decision-making process for performing randomized clinical trials for three drugs under consideration for repurposing for COVID-19 treatment: remdesivir, molnupiravir, and tenofovir disoproxil fumarate.

30 Mar 2023

$50 billion in opioid settlement cash is on the way. We’re tracking how it’s spent.

More than $50 billion in settlement funds is being delivered to thousands of state and local governments from companies accused of flooding their communities with opioid painkillers that have left millions addicted or dead.

30 Mar 2023

Anxiety attack or panic attack: Both may have come from the brain

An attack can come crashing in like a storm on a clear spring day. In an instant, your heart pounds, sweat soaks you and you struggle to breathe.

29 Mar 2023

Mapping neural connections in OCD patients can predict improvements after deep brain stimulation

Deep brain stimulation (DBS) is a promising therapy for treatment-resistant obsessive-compulsive disorder (OCD).

29 Mar 2023

Shape of the heart determines your risk for two common heart conditions

Curious to know if you're at risk for two common heart conditions? Your doctor may want to check the shape of your heart.

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Study paves the way for wider applications of cell reprogramming in medicine

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

29 Mar 2023

Scientists uncover novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health

A team of researchers from Ohio University's Heritage College of Osteopathic Medicine recently discovered a novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation -; the transplantation of living cells, tissues and organs from one species to another -; two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Lab-made antibodies may be able to cure people infected with yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

AI tool helps clinicians to identify and treat lung cancer at their early stages

A new artificial intelligence (AI) tool is helping physicians at Atrium Health Wake Forest Baptist better predict and diagnose lung cancer in patients.

29 Mar 2023

Study reveals dramatic rise in drug overdose fatalities among older adults in the past two decades

Overdose mortality among people age 65 and older quadrupled over 20 years, suggesting the need for greater mental health and substance use disorder policies addressed at curbing the trend, a new research paper finds.

29 Mar 2023

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

29 Mar 2023

ER’s error lands a 4-year-old in collections (for care he didn’t receive)

Dr. Sara McLin thought she made the right choice by going to an in-network emergency room near her Florida home after her 4-year-old burned his hand on a stove last Memorial Day weekend.

29 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

In a recent study published in the BMC Medicine journal, researchers in Sweden explored the association between above-optimal maternal gestational weight gain (GWG) and the risk of neurodevelopmental disorders such as intellectual disability, autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD) in offspring.

29 Mar 2023

Medicine News and Research

The decision-making process for the launch of trials for COVID-19 repurposed antivirals

$50 billion in opioid settlement cash is on the way. We’re tracking how it’s spent.

Anxiety attack or panic attack: Both may have come from the brain

Mapping neural connections in OCD patients can predict improvements after deep brain stimulation

Shape of the heart determines your risk for two common heart conditions

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Study paves the way for wider applications of cell reprogramming in medicine

Scientists uncover novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

Lab-made antibodies may be able to cure people infected with yellow fever

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

AI tool helps clinicians to identify and treat lung cancer at their early stages

Study reveals dramatic rise in drug overdose fatalities among older adults in the past two decades

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

ER’s error lands a 4-year-old in collections (for care he didn’t receive)

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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