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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

USC research uncovers previously unknown genetic risk factor for dementia

New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. The study provides insights on how these conditions, and other diseases of aging, might one day be treated and prevented.

21 Sep 2018

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel.

21 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Cobalt mining in DR Congo takes a high toll on both creuseurs and environment

In past years, the demand for cobalt has been on the increase due to its many applications. For one thing, the metal is a crucial component of rechargeable lithium-ion batteries for smartphones and electric cars.

20 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective.

20 Sep 2018

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Applied DNA Sciences Inc. announced today that LineaRx, Inc., its wholly-owned subsidiary focused on next-generation biotherapeutics, has signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L., biotechnology companies focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal markets, respectively.

20 Sep 2018

Genetic polymorphisms linked with muscle injury and stiffness

To test whether sex-related genetic polymorphisms are associated with muscle injury and stiffness, Noriyuki Fuku from Juntendo University and colleagues report in the journal Medicine & Science in Sports & Exercise that ESR1 rs2234693 polymorphism is associated with both muscle injury and muscle stiffness.

20 Sep 2018

Study could allow doctors to screen patients at risk from Aspergillus

Scientists at The University of Manchester have discovered a genetic mutation in humans linked to a 17-fold increase in the amount of dangerous fungal spores in the lungs.

20 Sep 2018

Researchers develop fast detection strategy to know type of virus acquired by patients

Even tiny amounts of viruses can have disastrous consequences. RNA identification can reveal the type of virus present.

20 Sep 2018

NIH and FDA call for eliminating involvement of RAC in human gene therapy experiments

Recently, the U.S. National Institutes of Health and Food and Drug Administration called for the eliminating involvement of the Recombinant DNA Advisory Committee in human gene therapy experiments, marking the end of an era of federal government oversight

20 Sep 2018

New study focuses on two-way gene switches controlling gene activity

Led by ICREA research professors at the Centre for Genomic Regulation, Luciano Di Croce and Marc A. Marti-Renom, the study focused on a set of genes with what's known as bivalent promoters - two-way genetic 'control switches' that are poised either to turn on in early development and rapidly drive high levels of gene activity, or to switch off and shut down the gene completely.

20 Sep 2018

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

Pediatric brain tumors are characterized by frequent complications due to intractable epilepsy compared to adult brain tumors. However, the genetic cause of refractory epilepsy in pediatric brain tumors has not been elucidated yet, and it is difficult to treat patients because the tumors do not respond to existing antiepileptic drugs and debilitate children's development.

19 Sep 2018

DermTech completes enrollment in clinical study to assess DNA damage and reversal

DermTech, Inc., the global leader in non-invasive molecular dermatology, announced today it has completed enrollment in a clinical study to assess DNA damage induced by an excimer laser and evaluate the potential of topical agents T4 endonuclease and photolyase to reduce DNA damage induced as measured through gene expression analysis.

19 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

As part of a national initiative to solve children's diseases, the Translational Genomics Research Institute and the Pacific Pediatric Neuro-Oncology Consortium are participating in the launch of the Kids First Data Resource Portal, which is supported by the National Institutes of Health .

19 Sep 2018

Henry Ford Health System receives $600k grant to study genetic makeup of gliomas

Henry Ford Health System's Department of Neurosurgery was awarded a $600,000 grant by the Department of Defense to study the genetic makeup of gliomas, a type of brain cancer, in hope of identifying new therapies.

19 Sep 2018

Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

Scientists discover new molecules that work together to remove unwanted DNA

Scientists have discovered a new family of molecules that work together to precisely remove unwanted DNA during reproduction in single-celled, freshwater organisms called ciliates.

19 Sep 2018

Researchers acquire new insights into DNA polymerases

Complex biological systems can be described as a network of chemical processes that take place in molecules. The scientists of the "ChemLife" research initiative at the University of Konstanz are working together in an equally active network with dynamic interconnections - both subject-specific and interdisciplinary.

19 Sep 2018

DNA News and Research

Further Reading

USC research uncovers previously unknown genetic risk factor for dementia

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Cobalt mining in DR Congo takes a high toll on both creuseurs and environment

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Genetic polymorphisms linked with muscle injury and stiffness

Study could allow doctors to screen patients at risk from Aspergillus

Researchers develop fast detection strategy to know type of virus acquired by patients

NIH and FDA call for eliminating involvement of RAC in human gene therapy experiments

New study focuses on two-way gene switches controlling gene activity

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

DermTech completes enrollment in clinical study to assess DNA damage and reversal

Researchers describe cell mechanism that optimizes proteins production in stressful situations

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

Henry Ford Health System receives $600k grant to study genetic makeup of gliomas

Penn researchers find common thread linking almost all TNR expansion diseases

Scientists discover new molecules that work together to remove unwanted DNA

Researchers acquire new insights into DNA polymerases

eBook: A guide to RNA sequencing eBook

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