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Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

28 Mar 2023

VR imaging system illuminates functional brain network dynamics in autism model

An international research collaboration has developed a VR imaging system that can measure a wide range of neural activity in the cortices of mice during active behavior.

28 Mar 2023

Surgeons can play an important role in reducing breast cancer disparities

Surgeons can play a key role in reducing breast cancer disparities by increasing their awareness of where disparities exist and having open conversations with their patients about their needs to initiate referrals early on in their care, according to a new collective review article published in the Journal of the American College of Surgeons.

28 Mar 2023

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

Some adults who take prescription medication for attention-deficit/hyperactivity disorder are required to have their urine tested for drugs several times a year. Others never are tested.

28 Mar 2023

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop often spreading to distant areas.

28 Mar 2023

University of Bath students building an artificial heart for the ‘Heart Hackathon’ competition

A team of University of Bath students are creating a working artificial heart as part of a worldwide ‘Heart Hackathon’ competition.

28 Mar 2023

Study finds best strategies to reduce the number of medication discrepancies in hospitals

A new study from researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, has shed new light on the best strategies hospitals can use for medication reconciliation, the critical and difficult task of updating and verifying a patient’s medication lists and orders, regardless of where they are in the health care system.

28 Mar 2023

Blood biomarkers could be used to predict a person's likelihood of developing PTSD

A new study found that people who are currently suffering or face a high risk of post-traumatic stress disorder show particular patterns in four biomarkers measurable with a simple blood test.

28 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

New primary care program for older adults lacks clinical benefits

A primary care program promoting the health of older adults was well received by family medical practices but lacked clinical benefits, says a study led by McMaster University researchers, published in the Annals of Family Medicine.

27 Mar 2023

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute to advance a new treatment approach for pancreatic cancer.

27 Mar 2023

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Researchers investigated the effects of the booster coronavirus disease 2019 (COVID-19) vaccine during pregnancy on COVID-19-related hospitalization rates among infants.

27 Mar 2023

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

New UCLA research in mice suggests that "dormant" cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

27 Mar 2023

Combination treatment for advanced endometrial cancer significantly reduces disease growth

In a study published in the March 27, 2023, online edition of the New England Journal of Medicine, researchers at the University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health found the combination of immunotherapy (pembrolizumab) and chemotherapy in patients with advanced or recurrent/advanced endometrial cancer resulted in a significant reduction in disease growth when compared with chemotherapy alone.

27 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

IU Cancer Center secures new, renewed ACS funding to support research and education programs

As part of a longstanding partnership, the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has received new and renewed funding from the American Cancer Society to support research and education programs.

27 Mar 2023

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

Sepsis occurs in approximately 1.7 million hospitalizations in the U.S. with in more than a third of hospitalizations resulting in death.

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Mount Sinai launches initiative to increase representation of Black men at the upper levels of management

The Mount Sinai Health System has announced the Growth in Operations, Administrations, and Leadership Society (GOALS), an initiative to increase the representation of Black men at the middle and upper levels of management by creating pathways for career advancement through networking, mentorship, and advancement opportunities.

27 Mar 2023

Medicine News and Research

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

VR imaging system illuminates functional brain network dynamics in autism model

Surgeons can play an important role in reducing breast cancer disparities

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

University of Bath students building an artificial heart for the ‘Heart Hackathon’ competition

Study finds best strategies to reduce the number of medication discrepancies in hospitals

Blood biomarkers could be used to predict a person's likelihood of developing PTSD

New study suggests broad neutralizing antibody could provide three years of COVID protection

New primary care program for older adults lacks clinical benefits

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

Combination treatment for advanced endometrial cancer significantly reduces disease growth

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

IU Cancer Center secures new, renewed ACS funding to support research and education programs

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Computational approach used to understand the mechanisms of protein folding in tauopathies

Mount Sinai launches initiative to increase representation of Black men at the upper levels of management

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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