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Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

The findings of a recent study indicate that routine testing with both fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC) may enhance the detection of ALK-positive non-small cell lung cancer (NSCLC).

25 Feb 2014

Researchers develop novel technique for detecting ALK rearrangements in non-small cell lung cancers

Researchers have developed a novel technique for detecting ALK rearrangements in non-small cell lung cancers (NSCLCs) that is more sensitive and easier to perform than currently available techniques.

25 Feb 2014

Scientists identify lung-damaging molecule in cystic fibrosis patients during symptom flare-ups

A molecule previously linked to lung injuries in factory workers producing microwave popcorn might play an important role in microbial infections of the lung suffered by people with cystic fibrosis (CF), according to a recent study led by San Diego State postdoctoral researcher Katrine Whiteson.

25 Feb 2014

UNM Cancer Center now adds stereotactic radiosurgery procedure to its list of treatment options

The UNM Cancer Center can now add stereotactic radiosurgery to its growing list of treatment options. This non-invasive outpatient procedure kills tumor cells in the brain in a single treatment.

24 Feb 2014

New system delivers anti-inflammatory drugs to immune cells gone out of control

Researchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology.

24 Feb 2014

State highlights: 'Health care homes' show promise in Minn.; Texas women's health providers; Fla.'s hidden costs

A selection of health policy stories from Minnesota, Texas, Louisiana, Florida, New York and Massachusetts.

24 Feb 2014

Blocking mechanisms for DNA repair may help to potentiate chemotherapy, says study

Chemotherapies are cancer treatments that work by inducing lesions in the DNA of tumour cells in order to inhibit their proliferation. However, the body naturally tries to repair these lesions, and thus reduces the efficacy of chemotherapy.

24 Feb 2014

Non-coding RNAs linked to cancer and cancer survival

Several scientists, including one at Simon Fraser University, have made a discovery that strongly links a little understood molecule, which is similar to DNA, to cancer and cancer survival.

21 Feb 2014

This winter, protect your family from radon gas

This time of year might feel too late for making New Year's resolutions, or too early for spring cleaning, but it's just the right time for taking an important step to protect the health your family: testing your home for radon, the second-leading cause of lung cancer.

21 Feb 2014

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

A large international study analyzing genes in tens of thousands of individuals has discovered 11 new genetic signals associated with blood pressure levels. Ten of those signals are in or very near genes encoding proteins that appear to be likely targets for drugs already in existence or in development.

21 Feb 2014

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Regional anesthesia may not make patients more prone to falls after knee replacement surgery

Two types of regional anesthesia do not make patients more prone to falls in the first days after having knee replacement surgery as some have previously suggested, according to a study based on nearly 200,000 patient records in the March issue of Anesthesiology.

21 Feb 2014

Study indicates relationship between multivitamin supplement use and cataract risk in men

Long-term daily multivitamin supplement use may lower cataract risk in men, according to a study of nearly 15,000 male physicians published this month in Ophthalmology, the journal of the American Academy of Ophthalmology

21 Feb 2014

Epidemiological studies demonstrate that diseases of central nervous system protect against cancer

Epidemiological studies demonstrate that diseases of the central nervous system such as Alzheimer, Parkinson and schizophrenia protect against cancer. The most remarkable example is Alzheimer's disease, which can reduce the risk of suffering from cancer by up to 50%.

21 Feb 2014

Ignyta reports preliminary results from ongoing Phase 1 clinical trial of RXDX-101

Ignyta, Inc., an oncology precision medicine biotechnology company, announced today that Justin Gainor, M.D., of the Massachusetts General Hospital Cancer Center, presented preliminary results from the ongoing Phase 1 dose escalation portion of a Phase 1/2 clinical trial of RXDX-101, Ignyta's proprietary oral tyrosine kinase inhibitor targeting solid tumor indications, at the International Association for the Study of Lung Cancer 14th Annual Targeted Therapies for the Treatment of Lung Cancer Meeting.

21 Feb 2014

HPV-positive patients with OPSCC show higher overall survival rate than HPV-negative patients

A retrospective analysis of oropharyngeal patients with recurrence of disease after primary therapy in the Radiation Therapy Oncology Group (RTOG) studies 0129 or 0522 found that HPV-positive patients had a higher overall survival (OS) rate than HPV-negative patients (at two years post-treatment, 54.6 percent vs. 27.6 percent, respectively), according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

20 Feb 2014

Predictors of bone metastasis, skeletal events in lung cancer identified

Researchers have identified a range of factors that are associated with the likelihood that a patient with advanced lung cancer will develop bone metastases or skeletal-related events.

20 Feb 2014

Lung cancer patients with Del19 mutation benefit most from afatinib

Afatinib has been approved in Germany since September 2013 for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer with activating EGF receptor mutations who have not been treated with an EGF receptor tyrosine-kinase inhibitor (EGFR TKI).

20 Feb 2014

Guerbet: FDA approves manufacturing plant for Lipiodol (ethiodized oil) Injection

Guerbet (GBT), the contrast agent specialist for medical imaging, today announced that it had received approval from the U.S. Food and Drug Administration (FDA) for a new manufacturing plant for Lipiodol® (ethiodized oil) Injection, in Montreal, Canada.

20 Feb 2014

Idiopathic pulmonary fibrosis could soon be diagnosed without the need for surgical lung biopsy

People who have suspected idiopathic pulmonary fibrosis without typical patterns on high resolution computed tomography scans could in future be spared the substantial risks of lung biopsy and be given a confident diagnosis of IPF based on clinical and radiological findings alone, according to new research published in The Lancet Respiratory Medicine.

20 Feb 2014

Lungs News and Research

Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

Researchers develop novel technique for detecting ALK rearrangements in non-small cell lung cancers

Scientists identify lung-damaging molecule in cystic fibrosis patients during symptom flare-ups

UNM Cancer Center now adds stereotactic radiosurgery procedure to its list of treatment options

New system delivers anti-inflammatory drugs to immune cells gone out of control

State highlights: 'Health care homes' show promise in Minn.; Texas women's health providers; Fla.'s hidden costs

Blocking mechanisms for DNA repair may help to potentiate chemotherapy, says study

Non-coding RNAs linked to cancer and cancer survival

This winter, protect your family from radon gas

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Regional anesthesia may not make patients more prone to falls after knee replacement surgery

Study indicates relationship between multivitamin supplement use and cataract risk in men

Epidemiological studies demonstrate that diseases of central nervous system protect against cancer

Ignyta reports preliminary results from ongoing Phase 1 clinical trial of RXDX-101

HPV-positive patients with OPSCC show higher overall survival rate than HPV-negative patients

Predictors of bone metastasis, skeletal events in lung cancer identified

Lung cancer patients with Del19 mutation benefit most from afatinib

Guerbet: FDA approves manufacturing plant for Lipiodol (ethiodized oil) Injection

Idiopathic pulmonary fibrosis could soon be diagnosed without the need for surgical lung biopsy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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