Immune System News and Research

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University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader.

5 Jan 2024

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Gut microbiome plays a role in immune response to mRNA COVID vaccines

Researchers from Karolinska Institutet in Sweden have discovered that the gut microbiome can influence how well people respond to mRNA COVID vaccines.

4 Jan 2024

Could your diet impact endometriosis? Research points to dietary insights for treatment

The role of dietary ingredients in modifying the progression and development of endometriosis.

4 Jan 2024

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

Study: High-fat diets impact genes in the intestines, brain, and immune system

A UC Riverside study to motivate your new year's resolutions: it demonstrates that high-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk.

3 Jan 2024

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window.

2 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

29 Dec 2023

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from immunotherapy treatment each year

28 Dec 2023

New model links RNA editing glitch to early-stage type 1 diabetes

Hebrew University study proposes a new model suggesting that disrupted RNA editing within pancreatic beta cells might initiate an inflammatory response akin to early-stage type 1 diabetes.

26 Dec 2023

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

Cedars-Sinai Cancer investigators have discovered a new way to predict whether a cancer of the immune system will recur in patients treated with a bone marrow transplant.

22 Dec 2023

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Researchers have identified a previously unrecognized class of antibodies-;immune system proteins that protect against disease-;that appear capable of neutralizing multiple forms of flu virus.

21 Dec 2023

R21/Matrix-M vaccine gets WHO green light for global rollout

The R21/Matrix-M™ malaria vaccine is one step closer to mass rollout, after officially receiving WHO prequalification status, making it eligible for procurement by United Nations agencies.

21 Dec 2023

Unraveling nuanced roles of JAK inhibitors in inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

21 Dec 2023

Scientists develop a method for tracking cellular events over time in living organisms

While physicists continue to argue about whether time is indeed an illusion, as Albert Einstein claimed, biologists have no doubt about its significance for understanding life as a dynamic system.

21 Dec 2023

UKHSA and ONS publish latest Winter CIS data

The Winter CIS was launched jointly by the UK Health Security Agency (UKHSA) and the Office for National Statistics (ONS) in November 2023 to deliver real-time prevalence and positivity data to aid the surveillance of COVID-19 in the community and help understand the winter pressures on the NHS.

21 Dec 2023

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Immune System News and Research

University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Stapled lipopeptides show promise as broad-spectrum antiviral agents

IKAROS: Unlocking the secrets of the immune system's key player

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Gut microbiome plays a role in immune response to mRNA COVID vaccines

Could your diet impact endometriosis? Research points to dietary insights for treatment

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study: High-fat diets impact genes in the intestines, brain, and immune system

Small molecule-switchable RNA platform enables control of therapeutic protein expression

How immune cells shape our earliest breaths

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

New model links RNA editing glitch to early-stage type 1 diabetes

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

R21/Matrix-M vaccine gets WHO green light for global rollout

Unraveling nuanced roles of JAK inhibitors in inflammation

Scientists develop a method for tracking cellular events over time in living organisms

UKHSA and ONS publish latest Winter CIS data

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