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Etoposide plus cisplatin remains best for limited-stage SCLC

Etoposide plus cisplatin, given alongside accelerated hyperfractionated thoracic radiotherapy, remains the gold standard regimen for patients with limited-stage small-cell lung cancer, Japanese researchers say.

23 Jan 2014

Prosonix announces positive top-line results from PSX1002 Phase 2 study for COPD treatment

Prosonix, an innovative speciality pharmaceutical company developing a portfolio of inhaled Respiratory Medicines by Design, announces positive top-line results from its Phase 2 clinical study with PSX1002 in patients with moderate to severe chronic obstructive pulmonary disease.

23 Jan 2014

Function of stem cells in blood-forming system is regulated by estrogen, says study

Scientists have known for years that stem cells in male and female sexual organs are regulated differently by their respective hormones. In a surprising discovery, researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) and Baylor College of Medicine have found that stem cells in the blood-forming system — which is similar in both sexes — also are regulated differently by hormones, with estrogen proving to be an especially prolific promoter of stem cell self-renewal.

23 Jan 2014

Home-based hospice practices for hospitalized patients could improve end-of-life care

A study by researchers at the Birmingham Veterans Affairs Medical Center and the University of Alabama at Birmingham says using home-based hospice practices for terminally ill, hospitalized patients could reduce suffering and improve end-of-life care.

23 Jan 2014

Starpharma receives approvals to commence phase 1 human clinical trial for DEP-Docetaxel

Starpharma today announced that it has received the necessary approvals to commence a phase 1 human clinical trial for its dendrimer-enhanced docetaxel (Taxotere®) chemotherapeutic product, referred to as DEP™-Docetaxel.

23 Jan 2014

New drug helps children and young adults who have severe pain from sickle cell disease

Saint Louis University researchers are studying whether ReoPro® (abciximab), a drug currently given to heart patients undergoing angioplasties to open blocked arteries, also could help children and young adults who have severe pain from sickle cell disease.

23 Jan 2014

ECMO: A last-resort therapy for extremely severe cases of influenza

Physicians at the University of Alabama at Birmingham are employing a technology known as ECMO as a last-resort therapy for extremely severe cases of influenza. ECMO, short for extracorporeal membrane oxygenation, is a sort of portable heart/lung bypass machine.

23 Jan 2014

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

The University of Texas MD Anderson Cancer Center will collaborate with Johnson & Johnson Innovation, LLC, and its affiliate Janssen Biotech, Inc., to develop immunology-based cancer treatments through the MD Anderson Moon Shots Program immunotherapy platform.

23 Jan 2014

NCCC physicians use new gene sequencing equipment for testing abnormal DNA in cancerous tumor cells

Clinical laboratory experts and physicians at Dartmouth-Hitchcock Norris Cotton Cancer Center (NCCC) achieved 100 percent accuracy in testing for abnormal DNA in cancerous tumor cells with its new gene sequencing equipment and panels.

23 Jan 2014

Jackson Laboratory collaborates with Seoul National University to develop new mouse models, tumor repository

The Jackson Laboratory, in collaboration with Seoul National University, will receive a five-year, $7.5 million grant from the South Korean government for a large-scale cancer genomics project employing the latest sequencing technology and special JAX mouse models that can host human tumors.

22 Jan 2014

Overdiagnosis concerns raised for CT lung cancer screening

People participating in any future computed tomography lung cancer screening program would face a significant risk for overdiagnosis, US researchers caution in JAMA Internal Medicine.

22 Jan 2014

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Dr. Beth Levine, a Howard Hughes Medical Institute Investigator and Director of the Center for Autophagy Research at UT Southwestern Medical Center, has received the 2014 Stanley J. Korsmeyer Award from the American Society for Clinical Investigation.

22 Jan 2014

Viewpoints: High Court's scrutiny of home health workers law; patient 'dumping' on LA's skid row; hospital fund raising

On Tuesday the Supreme Court will hear arguments in Harris v. Quinn, ... It was brought by the National Right to Work Legal Defense Foundation (NRTW), whose mission is to use "strategic litigation" to "eliminate coercive union power and compulsory unionism abuses," in this case on behalf of several personal assistants who provide in-home services to persons with disabilities under Illinois's Medicaid program.

22 Jan 2014

Mesothelioma patients treated with radiation before surgery experience speedier recovery

Results of clinical research that treated mesothelioma with radiation before surgery show the three-year survival rate more than doubled for study participants afflicted with this deadly disease, compared to treating with surgery first.

21 Jan 2014

Kolltan Pharmaceuticals announces treatment of first cancer patient with KTN3379

Kolltan Pharmaceuticals, a privately held biopharmaceutical company, today announced treatment of the first cancer patient with Kolltan's lead drug candidate, KTN3379, as part of a Phase 1 clinical study evaluating safety, preliminary evidence of antitumor activity, and pharmacokinetics. KTN3379 is a human monoclonal antibody that blocks the activity of ErbB3, a member of the ErbB family of receptor tyrosine kinases.

21 Jan 2014

Norris Cotton Cancer Center research estimates impact of R rating for movie smoking

The connection between smoking in films and its influence on adolescent behavior is well established by research and its impact was listed today in consumer materials accompanying the Surgeon General's Report: The Health Consequences of Smoking: 50 Years of Progress

20 Jan 2014

Going barefoot contributes to hookworm infections

Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters the body through the feet. By feeding on victims' blood, the worms cause anemia and, in children, stunted growth and learning problems.

20 Jan 2014

Vitamin D deficiency may lead to stiffening of blood vessels

UV-B radiation in sunlight is the most important factor for the production of vitamin D, and that is why many people suffer from low levels of vitamin D during the winter months.

20 Jan 2014

Research findings may offer new therapeutic target for management of Gaucher diseas

What causes brain damage and inflammation in severe cases of Gaucher disease? Little is known about the events that lead to brain pathology in some forms of the disease, and there is currently no treatment available - a bleak outlook for sufferers and their families. Now, scientists at the Weizmann Institute of Science have discovered a new cellular pathway implicated in Gaucher disease.

19 Jan 2014

Pulmonary Fibrosis Foundation selects UofL for newly established Care Center Network

The University of Louisville is one of nine pilot sites selected by the Pulmonary Fibrosis Foundation for its newly established Care Center Network and the PFF Patient Registry program. Rafael Perez, M.D., director of the UofL Interstitial Lung Disease program in the Division of Pulmonary, Critical Care & Sleep Disorders Medicine, will lead the UofL site.

17 Jan 2014

Lungs News and Research

Etoposide plus cisplatin remains best for limited-stage SCLC

Prosonix announces positive top-line results from PSX1002 Phase 2 study for COPD treatment

Function of stem cells in blood-forming system is regulated by estrogen, says study

Home-based hospice practices for hospitalized patients could improve end-of-life care

Starpharma receives approvals to commence phase 1 human clinical trial for DEP-Docetaxel

New drug helps children and young adults who have severe pain from sickle cell disease

ECMO: A last-resort therapy for extremely severe cases of influenza

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

NCCC physicians use new gene sequencing equipment for testing abnormal DNA in cancerous tumor cells

Jackson Laboratory collaborates with Seoul National University to develop new mouse models, tumor repository

Overdiagnosis concerns raised for CT lung cancer screening

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Viewpoints: High Court's scrutiny of home health workers law; patient 'dumping' on LA's skid row; hospital fund raising

Mesothelioma patients treated with radiation before surgery experience speedier recovery

Kolltan Pharmaceuticals announces treatment of first cancer patient with KTN3379

Norris Cotton Cancer Center research estimates impact of R rating for movie smoking

Going barefoot contributes to hookworm infections

Vitamin D deficiency may lead to stiffening of blood vessels

Research findings may offer new therapeutic target for management of Gaucher diseas

Pulmonary Fibrosis Foundation selects UofL for newly established Care Center Network

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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