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Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Scientists unearth a potential new target for treating age-related neurological diseases

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

8 Mar 2023

Review on factors related to variations in human microbiota

In a recent review published in Current Opinion in Microbiology, researchers reviewed existing data on variations in human microbiota, emphasizing on ageing- and ethnicity-associated changes in the microbiota.

8 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Study shows correlations between symptoms of long COVID and physical inactivity

The link between symptoms of COVID-19 and physical inactivity is increasingly evident.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

Enhanced recovery programs (ERPs) provide hospitals with the highest-quality resources to improve patient care for surgery, but many hospitals still struggle to successfully implement these programs and may need more structured resources to boost compliance rates, according to findings published in the Journal of the American College of Surgeons.

8 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Racism contributes to disproportionate newborn drug testing

If a newborn tests positive for certain drugs after birth, mandated reporters in many states – including health care professionals and social workers – are required to report it to Child Protective Services.

8 Mar 2023

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

The University of Utah, one of the nation's leading research universities, and TikkunLev Therapeutics, a gene therapy company, have announced a new partnership to accelerate an innovative heart-failure gene therapy.

8 Mar 2023

$Male geriatric patients at greater risk of skull fractures from falls than females$

Male geriatric patients at greater risk of skull fractures from falls than females

Each year, more than 3 million people ages 65 and older are treated in emergency departments for fall injuries. Head trauma is the leading cause of serious injury with skull fractures being reported as a serious outcome.

8 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Poor sleep associated with different durations of compromised cardiovascular health

Poor sleep could lead to between two and seven years worth of heightened heart disease risk and even premature death, according to a new study led by researchers at the University of Sydney in collaboration with Southern Denmark University.

8 Mar 2023

Newly diagnosed atrial fibrillation linked to modestly elevated risk of dementia

In a large study of diverse adults in California, individuals with newly diagnosed atrial fibrillation, or an irregular heart rhythm, had a modestly elevated risk of developing dementia.

8 Mar 2023

Reentry programs to help former prisoners obtain health care are often underused

When Matthew Boyd was released from a Georgia state prison in December 2020, officials sent him home without medicines he uses to manage chronic heart and lung conditions and high blood pressure, he said.

8 Mar 2023

Newly identified bone matrix protein may help treat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

8 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

7 Mar 2023

Medicine News and Research

Microglia partner with T cells to cause neurodegeneration, study shows

Scientists unearth a potential new target for treating age-related neurological diseases

Review on factors related to variations in human microbiota

Study suggests a new approach for treating metastatic breast cancers

Study shows correlations between symptoms of long COVID and physical inactivity

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

COVID-19 patients at increased risk of developing gastrointestinal disorders

Racism contributes to disproportionate newborn drug testing

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

Male geriatric patients at greater risk of skull fractures from falls than females

Discovery could lead to effective treatments for acute alcohol intoxication

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Poor sleep associated with different durations of compromised cardiovascular health

Newly diagnosed atrial fibrillation linked to modestly elevated risk of dementia

Reentry programs to help former prisoners obtain health care are often underused

Newly identified bone matrix protein may help treat osteosarcoma

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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