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Late-breaking abstracts on treatment of blood cancers and bleeding disorders presented at ASH meeting

A range of studies highlighting late-breaking research advances in the understanding and treatment of blood cancers and bleeding disorders are being presented today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans.

12 Dec 2013

Findings help inform ongoing discussions regarding potential changes to US' lung allocation policy

A new analysis has found no evidence that children aged 6 to 11 years seeking a deceased donor lung transplant are disadvantaged in the current US lung allocation system. The findings, which are published in the American Journal of Transplantation, help inform ongoing discussions regarding potential changes to the nation's lung allocation policy.

12 Dec 2013

Findings may help clinicians determine which hospitalized children at greatest risk of VTE

Life-threatening blood clots occur so rarely in children that the condition, known as venous thromboembolism (VTE), is often not on pediatricians' mental radar screens - an absence that can lead to woefully delayed recognition and treatment.

12 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

New mechanism explains why anti-tumor activity of specific immune suppressed during tumor growth

The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth. They have also demonstrated that blocking the protein Nrp1 can restore this anti-tumor immune response.

12 Dec 2013

HSET protein could help doctors identify aggressive breast cancers in African-American patients

African-American women who get breast cancer often get more aggressive forms of the disease and at younger ages than other women.

12 Dec 2013

People more likely to seek info on quitting smoking when media covers celebrities with cancer

Millions of people will make a resolution to quit smoking around Jan. 1, but a new study suggests an even more powerful motivator than New Year's resolutions: celebrity cancer diagnoses.

12 Dec 2013

New test to help physicians identify patients with most lethal forms of triple-negative breast cancer

A new test has the potential to help physicians identify patients with the most lethal forms of triple-negative breast cancer, a disease which requires aggressive and innovative treatment.

12 Dec 2013

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

A recent Mayo Clinic study found that people with chronic obstructive pulmonary disease (COPD) are about twice as likely to develop mild cognitive impairment (MCI) -- and chances are that it will include memory loss. The study was recently published in Mayo Clinic Proceedings.

12 Dec 2013

New guidelines developed to manage heart failure in children with undiagnosed heart disease

12 Dec 2013

Johns Hopkins researchers use lung cancer drug to shrink chordoma in mice

Johns Hopkins researchers say that a drug approved to treat lung cancer substantially shrank tumors in mice that were caused by a rare form of bone cancer called chordoma.

12 Dec 2013

Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

Pharmacyclics, Inc. today announced results of 40 clinical, non-clinical and pre-clinical presentations on ibrutinib (IMBRUVICA™) at the 55TH Annual meeting of the American Society of Hematology (ASH) held in New Orleans, Dec 7 - 10, 2013.

11 Dec 2013

New review calls for action to reduce illness and death from silica exposure at work

A new review highlights new developments in understanding the health effects of silica, and calls for action to reduce illness and death from silica exposure at work, including stronger regulations, heightened awareness and prevention, and increased attention to early detection of silicosis and lung cancer using low dose CT scanning.

11 Dec 2013

Pemetrexed, paclitaxel regimens equally effective in NSCLC

PointBreak trial results suggest that pemetrexed- and paclitaxel-based chemotherapy offer comparable survival outcomes and tolerability for patients with advanced nonsquamous non-small-cell lung cancer (NSCLC) but with differing toxicity profiles.

10 Dec 2013

Researchers explain why anti-tumor activity of specific immune cells suppress during tumor growth

The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth.

10 Dec 2013

Study finds large degree of genetic variation amongst M. tuberculosis in humans in Zambia

In Zambia, the incidence of all forms of human tuberculosis is estimated to be 444 per 100,000. There is also a high incidence of HIV and AIDS in the country. In the Kafue area, a high incidence of Mycobacterium bovis in both cattle and the Kafue lechwe antilope has been detected. This bacterium can infect humans and has been found in humans in the studied region of Namwala. Mycobacterium tuberculosis, which is the main cause of human tuberculosis, has also been detected in cattle in this region.

10 Dec 2013

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

In nearly one-third of patients with Waldenstrom's Macroglobulinemia, a specific genetic mutation switches on the disease, and a new drug that blocks the defective gene can arrest the disease in animal models, researchers at Dana-Farber Cancer Institute and allied institutions will report at the 2013 annual meeting of the American Society of Hematology.

10 Dec 2013

IBN and IBM discover new medical application for converted PET bottles

Researchers at Singapore's Institute of Bioengineering and Nanotechnology (IBN) and California's IBM Research - Almaden (IBM) have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles.

10 Dec 2013

CRAB CTC enrolls first patient into inaugural cancer clinical trial

Cancer Research And Biostatistics today announced enrollment of the first patient into the inaugural clinical trial sponsored by its Clinical Trials Consortium. The CRAB CTC mission is to ensure rapid clinical testing of new and innovative cancer treatments, and is focusing on lung cancer as its first target. By engaging frontline treating oncologists to push the boundaries of patient care, the aim is to improve the standard of care and extend overall survival.

9 Dec 2013

Lung cancer screening using low-dose CT reduces mortality in high-risk smokers

Previous evidence, including published National Lung Cancer Screening Trial (NLST) results, shows that computed tomography (CT) lung cancer screening significantly reduces lung cancer deaths in high risk patients*, and is appropriate, with careful patient selection and follow-up.

9 Dec 2013

Lungs News and Research

Late-breaking abstracts on treatment of blood cancers and bleeding disorders presented at ASH meeting

Findings help inform ongoing discussions regarding potential changes to US' lung allocation policy

Findings may help clinicians determine which hospitalized children at greatest risk of VTE

New guidelines to manage heart failure in children

New mechanism explains why anti-tumor activity of specific immune suppressed during tumor growth

HSET protein could help doctors identify aggressive breast cancers in African-American patients

People more likely to seek info on quitting smoking when media covers celebrities with cancer

New test to help physicians identify patients with most lethal forms of triple-negative breast cancer

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

New guidelines developed to manage heart failure in children with undiagnosed heart disease

Johns Hopkins researchers use lung cancer drug to shrink chordoma in mice

Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

New review calls for action to reduce illness and death from silica exposure at work

Pemetrexed, paclitaxel regimens equally effective in NSCLC

Researchers explain why anti-tumor activity of specific immune cells suppress during tumor growth

Study finds large degree of genetic variation amongst M. tuberculosis in humans in Zambia

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

IBN and IBM discover new medical application for converted PET bottles

CRAB CTC enrolls first patient into inaugural cancer clinical trial

Lung cancer screening using low-dose CT reduces mortality in high-risk smokers

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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