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New hand-held device can help prevent thousands of unnecessary TB deaths

Thousands of deaths from tuberculosis, an infectious bacterial disease, could be prevented using a new hand-held device that is being developed to detect potentially fatal drug resistance in less than 15 minutes.

7 Nov 2013

New study looks at hormone/SNS relationship in women taking hormone contraceptives

After menopause, women's levels of estrogen and progesterone fall. Their formerly lower risk for heart disease equals, even surpasses, men's risk. One possible contributing explanation for the change in risk is that sex hormones affect the sympathetic nervous system, which controls constriction of blood vessels and participates in the fight or flight response.

7 Nov 2013

New study could help lead to prevention and treatment of heart failure in diabetics

Researchers from the University of Texas Medical Branch at Galveston have discovered one of the pathogenic components of diabetes in the heart, as published in the Journal of Biological Chemistry.

7 Nov 2013

Tea helps promote weight loss and improve bone health

Decades worth of research shows that tea-the second most consumed beverage in the world-may help prevent chronic illnesses, including heart disease, certain types of cancer and type 2 diabetes. New research shows tea has been found to help promote weight loss and maintain a healthy weight, improve bone health and activate areas of the brain that bolster attention, problem solving and mood.

7 Nov 2013

New drug combination therapy effectively kills cancer cells

Results from a recent preclinical study have shown that a new drug combination therapy being developed at Virginia Commonwealth University Massey Cancer Center effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients.

6 Nov 2013

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and Five Prime Therapeutics, Inc., a clinical-stage biotechnology company focused on discovering and developing novel protein therapeutics for cancer and inflammatory diseases, today announced an exclusive license agreement for human antibodies directed to an undisclosed target expressed on the surface of various types of cancers.

6 Nov 2013

ImmunoGen starts clinical testing with its EGFR-targeting ADC, IMGN289 for several types of cancers

ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops novel anticancer therapeutics using its ADC technology, today announced the start of clinical testing with its EGFR-targeting ADC, IMGN289.

6 Nov 2013

ImmunoGen decides to stop IMGN901 Phase II SCLC study

ImmunoGen, Inc., a biotechnology company that develops novel anticancer therapeutics using its antibody-drug conjugate technology, announced today the decision to stop the IMGN901 Phase II SCLC study, following the recommendation of the trial's independent Data Monitoring Committee.

6 Nov 2013

Insomnia concerns go unaddressed in heart failure patients

The impact of insomnia on health and function is a major concern for patients with heart failure, qualitative and quantitative research shows.

5 Nov 2013

NTU establishes new $60 million research institute in Nanomedicine

Nanyang Technological University is giving the development of nanotechnology a big boost, by establishing a new $60 million research institute in Nanomedicine, which focuses on the medical application of nanotechnology. An emerging field in drugs, nanomedicine are made up of tiny nano-sized particles thousands of times smaller than a grain of sand.

5 Nov 2013

Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Whitehead Institute scientists report that the gene mutated in the rare hereditary disorder known as Birt-Hogg-Dub- cancer syndrome also prevents activation of mTORC1, a critical nutrient-sensing and growth-regulating cellular pathway.

5 Nov 2013

Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Biothera announced today top-line results from its Phase 2b clinical trial in non-small cell lung cancer (NSCLC) that evaluated its immunotherapeutic drug candidate, Imprime PGG®, with cetuximab (Erbitux®), carboplatin and paclitaxel compared with the monoclonal antibody and chemotherapy combination alone.

5 Nov 2013

New method for quickly ruling out serious acute coronary disease of chest pains

Researchers at Karolinska Institutet in Sweden have tested a new method for quickly ruling out acute myocardial infarction or other serious acute coronary disease in Emergency department patients complaining of chest pains.

5 Nov 2013

California gets 'A' grade on March of Dimes 2013 Premature Birth report card

California has improved its grade on the March of Dimes 2013 Premature Birth report card, moving from a 'B' grade in 2012 to an 'A' grade in 2013.

4 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

Study examines impact of sleep on children's eating behaviors

It seems everyone is looking for a culprit when it comes to childhood obesity: fast food, sugary drinks, super-sized everything. But it turns out part of the blame may lie with the simple matter of turning out the lights and rolling into bed.

4 Nov 2013

Healthcare-associated infections are less likely to occur in favorable critical care work environments

Healthcare-associated infections (HAIs) are less likely to occur in favorable critical care work environments, according to a study of more than 3,200 nurses in the November issue of American Journal of Critical Care (AJCC).

4 Nov 2013

Experimental drug effective in treating patients with non-small cell lung cancer

An experimental cancer drug that has shown promise in the treatment of melanoma has also shown early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death among men and women worldwide.

4 Nov 2013

Heart failure patients may benefit from advanced treatment by heart specialists

New research from Karolinska Institutet in Sweden shows that patients with heart failure have high mortality and often are undertreated. According to a study, published in the scientific periodical JACC, many more of these patients would benefit from advanced treatment by heart specialists - something that could be decided by a simple evaluation of five common risk factors for early death due to heart failure.

4 Nov 2013

Lungs News and Research

New hand-held device can help prevent thousands of unnecessary TB deaths

New study looks at hormone/SNS relationship in women taking hormone contraceptives

New study could help lead to prevention and treatment of heart failure in diabetics

Tea helps promote weight loss and improve bone health

New drug combination therapy effectively kills cancer cells

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

ImmunoGen starts clinical testing with its EGFR-targeting ADC, IMGN289 for several types of cancers

ImmunoGen decides to stop IMGN901 Phase II SCLC study

Insomnia concerns go unaddressed in heart failure patients

NTU establishes new $60 million research institute in Nanomedicine

Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Researchers identify factor that promotes metastasis of colon tumors

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

New method for quickly ruling out serious acute coronary disease of chest pains

California gets 'A' grade on March of Dimes 2013 Premature Birth report card

LMU researchers identify a factor that promotes metastasis of colon tumors

Study examines impact of sleep on children's eating behaviors

Healthcare-associated infections are less likely to occur in favorable critical care work environments

Experimental drug effective in treating patients with non-small cell lung cancer

Heart failure patients may benefit from advanced treatment by heart specialists

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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