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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry Bioorganic Chemistry Award for his ground-breaking contributions to the expansion of the genetic alphabet.

9 May 2018

Massachussetts public health department receives $100,000 grant to subsidize cost of tick testing

A recent report from the Centers for Disease Control and Prevention that warns of a recent surge of tick-borne disease incidence in the United States was no surprise to Massachusetts State Public Health Veterinarian Dr. Catherine Brown and microbiology professor Stephen Rich, director of the Laboratory of Medical Zoology at the University of Massachusetts Amherst.

9 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Human papilloma virus vaccines can protect against cervical lesions in young women

New evidence published today in the Cochrane Library shows that human papilloma virus vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Flushing the bladder with common chemotherapy drug after surgery can reduce bladder cancer recurrence

Flushing the bladder with a common chemotherapy drug immediately after surgery significantly reduces the chances of bladder cancer returning, according to a major study by SWOG, an international clinical trials network funded by the National Cancer Institute.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Cancer is most devastating when it metastasizes--when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

DNA News and Research

Further Reading

Study discovers genetic variations that increase heart attack risk for statin patients

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Massachussetts public health department receives $100,000 grant to subsidize cost of tick testing

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

Human papilloma virus vaccines can protect against cervical lesions in young women

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Findings confirm analytical principle that describes mutational processes and cancer development

Flushing the bladder with common chemotherapy drug after surgery can reduce bladder cancer recurrence

New findings point to potential therapeutic avenues for leukemia

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Cancer scientists confirm oligometastasis hypothesis

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Researchers discover how key brain receptor can function in hostile environment

Discovery could be used as starting point for development of new antibiotics

Study finds diverse mix of bacteria in the urine of kidney disease patients

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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