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Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

Preconception diabetes and prediabetes associated with increased risk of preterm birth

A new study examined the associations between preconception diabetes, prediabetes, and hemoglobin A1c (HbA1c) levels on the risk of preterm birth.

22 Feb 2023

How are adverse childhood events and less than ideal cardiovascular health in adulthood associated?

Researchers evaluated associations between adverse childhood events (ACEs) and cardiovascular health (CVH).

22 Feb 2023

Women who have quality relationships less likely to develop multiple chronic conditions in older age

University of Queensland research has found women who have quality relationships in their 40s and 50s are less likely to develop multiple chronic conditions in older age.

22 Feb 2023

Home healthcare clinics provide better end-of-life care than general hospitals, study shows

One of the ironies of old age is that the more care and support we need, the harder it can be to access it, given increasing limitations in mobility and independence.

22 Feb 2023

First smart wearable device tracks how much people use their voices

Northwestern University researchers have developed the first smart wearable device to continuously track how much people use their voices, alerting them to overuse before vocal fatigue and potential injury set in.

22 Feb 2023

Specific group of COVID-19 patients benefits the most from remdesivir, new analysis shows

Remdesivir was one of the first medications approved for treatment of COVID-19. Clinical studies evaluated its effectiveness, but did not generate conclusive results.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe.

22 Feb 2023

Challenges associated with prescribing exercise to diabetic patients taking metformin

In a recent study published in the Sports Medicine and Health Science journal, researchers assessed the impact of exercise precision medicine on type 2 diabetes.

21 Feb 2023

Research identifies potential treatment target for infantile spasms syndrome

New research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences suggests that the timing of the death of certain inhibitory neurons in the brain shortly after birth may be at least partly to blame for infantile spasms syndrome (ISS), a rare but devastating form of epilepsy that develops most frequently between four and eight months of age but can emerge within weeks of birth until ages 4 or 5.

21 Feb 2023

Alternative splicing plays a role in compensating for loss of gene function

Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.

21 Feb 2023

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

The University of Ottawa's Dr. Mamta Gautam is the first awardee of the AFMC Wellness Award, a new national honor that recognizes an individual in Canada who has shown dedication to the promotion and advancement of the wellness of physicians, medical students, and others.

21 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

A long-acting antiretroviral treatment (LA-ART) given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed.

21 Feb 2023

Medicaid expansion may improve outcomes for children with cancer

Medicaid expansion may improve outcomes for children with cancer, finds a new analysis from the Brown School and Washington University School of Medicine in St. Louis.

21 Feb 2023

Cleveland Clinic researchers receive $3.14 million NIH grant to use “digital twins” for reducing healthcare disparities

Supported by a new $3.14 million grant from the National Institutes of Health to Cleveland Clinic, researchers are using an emerging technology known as "digital twins" to better understand healthcare disparities based on where someone lives.

21 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Skin medication shows promise in treating alcohol use disorder

Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an "incredibly promising" treatment for alcohol use disorder.

21 Feb 2023

Medicine News and Research

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Preconception diabetes and prediabetes associated with increased risk of preterm birth

How are adverse childhood events and less than ideal cardiovascular health in adulthood associated?

Women who have quality relationships less likely to develop multiple chronic conditions in older age

Home healthcare clinics provide better end-of-life care than general hospitals, study shows

First smart wearable device tracks how much people use their voices

Specific group of COVID-19 patients benefits the most from remdesivir, new analysis shows

Dietary polyphenols may play a role in regulating inflammatory immune responses

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Challenges associated with prescribing exercise to diabetic patients taking metformin

Research identifies potential treatment target for infantile spasms syndrome

Alternative splicing plays a role in compensating for loss of gene function

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

Medicaid expansion may improve outcomes for children with cancer

Cleveland Clinic researchers receive $3.14 million NIH grant to use “digital twins” for reducing healthcare disparities

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Skin medication shows promise in treating alcohol use disorder

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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