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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New studies related to causes of liver degradation and possible treatments

A treatment gap remains for many conditions involving damage to the liver, the body's main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

23 Apr 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

Scientists identify gene responsible for evolution of recombination rates

Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, however, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.

20 Apr 2018

Drawbacks and benefits of using saliva for epigenetic studies

Biomarkers in saliva identify changes that impact the body, according to research published in Current Genomics. This important paper details the drawbacks and benefits of using saliva as a tissue sample for the study of epigenetic changes affected by experiences.

20 Apr 2018

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Triple-negative breast cancer is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment.

20 Apr 2018

Newly developed drug compound may help treat Charcot-Marie-Tooth disease

Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet and legs.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

Evolutionary history of tumor helps predict severity of prostate cancer

Findings from Canadian Prostate Cancer Genome Network (CPC-GENE) researchers and their collaborators, published today in Cell, show that the aggressiveness of an individual prostate cancer can be accurately assessed by looking at how that tumor has evolved. This information can be used to determine what type and how much treatment should be given to each patient, or if any is needed at all.

20 Apr 2018

High-tech microscope reveals how cancer-causing virus anchors itself to human DNA

Using a homemade, high-tech microscope, scientists at the University of Virginia School of Medicine have revealed how a cancer-causing virus anchors itself to our DNA. That discovery could pave the way for doctors to cure incurable diseases by flushing out viruses, including HPV and Epstein-Barr, that now permanently embed themselves in our cells.

20 Apr 2018

New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

Academia and high tech companies join forces to increase production capacity for microfluidic systems

The University of Twente, Saxion University of Applied Sciences and four high tech companies are combining forces to increase the production capacity for microfluidic systems. As part of this pilot line project (“proeftuin”), they are improving access for SMEs to their facilities, including the MESA+ NanoLab and High Tech Factory.

From Micronit Microtechnologies B.V. 20 Apr 2018

AYOXXA launches advanced low-volume beads-on-a-chip multiplex protein analysis system

AYOXXA Biosystems GmbH, an international biotechnology company, today announces the introduction of its advanced low-volume beads-on-a-chip multiplex protein analysis system. The LUNARIS™ system can be readily integrated into any laboratory routine and is optimized to provide easy-to-use, standardized workflow from sample to result.

20 Apr 2018

Rare variants in non-coding DNA inherited from parents heighten autism risk

In recent years, researchers have firmly established that gene mutations appearing for the first time, called de novo mutations, contribute to approximately one-third of cases of autism spectrum disorder.

20 Apr 2018

GNA Biosolutions to display Pharos V8 Laser PCR instrument at Analytica trade fair

GNA Biosolutions GmbH will be showcasing the Pharos V8, the world’s first Laser PCR instrument based on the company’s proprietary Pulse Controlled Amplification technology at the Analytica trade fair in Munich, Germany from April 10-13. Launched in November 2017, the Pharos V8 delivers ultrafast PCR results in 10 minutes or less.

From HP Health Solutions Germany GmbH 20 Apr 2018

GNA Biosolutions and project partners launch new research project to develop TB diagnostic platform for POC applications

Molecular technology company GNA Biosolutions GmbH and its project partners announced the launch of PITBUL, a European Commission funded international research project aimed at developing a tuberculosis (TB) diagnostic platform to be utilized at the Point of Care.

From HP Health Solutions Germany GmbH 20 Apr 2018

Triple-negative breast cancer found to be chemoresistant prior to treatment

Difficult to treat and aggressive "triple-negative" breast cancer is chemoresistant even before chemotherapy begins, a new study by researchers from Karolinska Institutet and the University of Texas MD Anderson Cancer Center reports. The findings, which are published in the journal Cell, may lead to better and more personalized treatments for breast cancer.

19 Apr 2018

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios.

19 Apr 2018

UGA scientist creates system for efficient detection of foodborne pathogens

Quick, efficient pathogen detection and fingerprinting is essential and often lifesaving when it comes to preventing foodborne illness. Now, University of Georgia food scientist Xiangyu Deng has created a system that can identify foodborne pathogens in a fraction of the time taken by traditional methods.

18 Apr 2018

New study maps links between 625 genes and different chemotherapy treatments

Despite the great successes of targeted cancer drugs and the promise of novel immunotherapies, the vast majority of people diagnosed with cancer are still first treated with chemotherapy. Now a new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use the genetic profile of a patient's tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.

18 Apr 2018

Scientists decipher mechanism of chemotherapy induced female infertility

Many chemotherapeutics act by damaging the DNA. Since cancer cells divide more often than most normal cells, they react more sensitive to DNA damaging agents.

17 Apr 2018

DNA News and Research

Further Reading

New studies related to causes of liver degradation and possible treatments

Study examines how higher-order gene combinations help maintain normal cell physiology

Scientists identify gene responsible for evolution of recombination rates

Drawbacks and benefits of using saliva for epigenetic studies

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Newly developed drug compound may help treat Charcot-Marie-Tooth disease

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Evolutionary history of tumor helps predict severity of prostate cancer

High-tech microscope reveals how cancer-causing virus anchors itself to human DNA

New CRISPR tool allows DNA editing outside of the cell

Academia and high tech companies join forces to increase production capacity for microfluidic systems

AYOXXA launches advanced low-volume beads-on-a-chip multiplex protein analysis system

Rare variants in non-coding DNA inherited from parents heighten autism risk

GNA Biosolutions to display Pharos V8 Laser PCR instrument at Analytica trade fair

GNA Biosolutions and project partners launch new research project to develop TB diagnostic platform for POC applications

Triple-negative breast cancer found to be chemoresistant prior to treatment

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

UGA scientist creates system for efficient detection of foodborne pathogens

New study maps links between 625 genes and different chemotherapy treatments

Scientists decipher mechanism of chemotherapy induced female infertility

eBook: A guide to RNA sequencing eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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