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Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category.

15 Feb 2023

Study highlights increased risks for young pregnant adolescents compared with older teens, adults

Young adolescents face different challenges in pregnancy compared with their older teenage peers and adults that are sometimes exacerbated by high rates of obesity, a new study by UT Southwestern researchers suggests.

15 Feb 2023

Sleep irregularity may increase the risk for atherosclerosis

Sleep irregularity -; chronically disrupted sleep and highly variable sleep durations night after night -; may increase the risk for atherosclerosis, according to a study led by Kelsie Full, PhD, MPH, of Vanderbilt University Medical Center.

15 Feb 2023

Increasing numbers of cancer survivors at high risk for cardiovascular disease

American Cancer Society (ACS) research estimates there are more than 18 million adult survivors of cancer in the United States, and that number is expected to climb to more than 22 million by 2030.

15 Feb 2023

Researchers identify a novel mechanism of DNA repair that occurs in neurons

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.

15 Feb 2023

Computational modeling helps uncover genomic mutations that likely influenced human cognition

Researchers from the National Institutes of Health (NIH) used computational modeling to uncover mutations in the human genome that likely influenced the evolution of human cognition.

15 Feb 2023

Irregular sleeping habits linked to atherosclerosis risk in older adults

Sleeping an inconsistent number of hours each night and falling asleep at different times may increase the risk of developing atherosclerosis among adults older than 45 compared to people with more consistent sleep habits, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

15 Feb 2023

Novel predictive index for gastric cancer prognosis

A new research paper was published in Oncotarget's Volume 14 on January 31, 2023, entitled, "Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer."

15 Feb 2023

Nusinersen treatment improves spinal muscular atrophy patients’ walking distance

A positive effect of nusinersen treatment on motor function in ambulant pediatric and adult spinal muscular atrophy (SMA) patients during a 38-month period has been demonstrated by an analysis of data from the SMArtCARE registry.

15 Feb 2023

Higher intake of free sugars linked with increased risk of cardiovascular disease

Higher intake of free sugars – added sugars and those naturally present in honey and fruit juice – is associated with a higher risk of cardiovascular disease, reports a study published in BMC Medicine.

15 Feb 2023

B lymphocytes play a pivotal role in promoting an emergent response during infection

An SOS signals a call for immediate action during an emergency to request a need for protection. The immune system, a network of defense mechanisms, enhances protection to recover the body's internal stability.

15 Feb 2023

Study: Organ damage persists in 59% of COVID patients a year after initial symptoms

A new comprehensive study of organ impairment in long COVID patients over twelve months shows organ damage persisted in 59% of patients a year after initial symptoms, even in those not severely affected when first diagnosed with the virus.

15 Feb 2023

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

Researchers from Johns Hopkins Medicine and several other institutions say they have developed a quick clinical test that predicts which people with neck pain are more likely to benefit from epidural steroid injections, which deliver drugs directly around the spinal nerves to stop nerve inflammation and reduce pain.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Many people living on the streets in Philadelphia's Kensington neighborhood — the largest open-air drug market on the East Coast — are in full-blown addiction, openly snorting, smoking, or injecting illicit drugs, hunched over crates or on stoops. Syringes litter sidewalks, and the stench of urine fouls the air.

15 Feb 2023

Armed with hashtags, these activists made insulin prices a presidential talking point

Hannah Crabtree got active on Twitter in 2016 to find more people like herself: those with Type 1 diabetes who'd hacked their insulin pumps to automatically adjust the amount of insulin delivered.

15 Feb 2023

Aerosol experts provide an account of the rejection of aerosol science by the WHO

In a recent viewpoint article published in the journal Clinical Infectious Diseases, researchers underscored the need for prompt adoption of scientific evidence, using the delayed acceptance of the airborne mode of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission as an example.

15 Feb 2023

Medicine News and Research

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

Study highlights increased risks for young pregnant adolescents compared with older teens, adults

Sleep irregularity may increase the risk for atherosclerosis

Increasing numbers of cancer survivors at high risk for cardiovascular disease

Researchers identify a novel mechanism of DNA repair that occurs in neurons

Computational modeling helps uncover genomic mutations that likely influenced human cognition

Irregular sleeping habits linked to atherosclerosis risk in older adults

Novel predictive index for gastric cancer prognosis

Nusinersen treatment improves spinal muscular atrophy patients’ walking distance

Higher intake of free sugars linked with increased risk of cardiovascular disease

B lymphocytes play a pivotal role in promoting an emergent response during infection

Study: Organ damage persists in 59% of COVID patients a year after initial symptoms

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Armed with hashtags, these activists made insulin prices a presidential talking point

Aerosol experts provide an account of the rejection of aerosol science by the WHO

Study reveals how astrocytes of socially-isolated mice cause learning and memory deficits

Meta-analysis showcases the long-term benefits of COVID-19 vaccines against hospitalization & death

Night shift work may make offshore petroleum workers more susceptible to aggressive prostate cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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