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miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Determining whether a patient's lung cancer has spread to nearby lymph nodes is critical for identifying the most effective therapy, but it usually requires surgery. A new study suggests, however, that measuring levels of a particular molecule in a sample of tumor tissue might accurately answer the question.

25 Sep 2013

Metastatic site impacts survival in targeted RCC treatment

Bone and liver metastases may have the heaviest impact on the survival of patients receiving targeted therapy for metastatic renal cell carcinoma, suggest data from the International Metastatic Renal Cell Carcinoma Database Consortium.

24 Sep 2013

Changes in national diets linked to dramatic rise in AD prevalence in Japan and developing countries

In a paper just published electronically in the Journal of Alzheimer's Disease, dramatic increases in Alzheimer's disease in Japan and significant increases in developing countries are linked to changes in national diets.

24 Sep 2013

Messages that warn consumers about potentially harmful side effects increase product sales

Drug ads often warn of serious side effects, from nausea and bleeding to blindness, even death. New research suggests that, rather than scaring consumers away, these warnings can improve consumers' opinions and increase product sales when there is a delay between seeing the ad and deciding to buy or consume the product.

24 Sep 2013

Depression in cancer patients who receive RT can be identified by 2-item questionnaire

Cancer patients receiving radiotherapy (RT) who are potentially suffering from depression can be effectively identified by a two-item questionnaire, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.

24 Sep 2013

ACR journals publish guide that provides new treatments for children with systemic JIA

In the U.S., there are nearly 300,000 children with juvenile arthritis and other rheumatic illnesses according to estimates from the American College of Rheumatology (ACR). For pediatric patients with systemic juvenile idiopathic arthritis (JIA), effective treatment for this disabling disease is imperative.

24 Sep 2013

Lung cancer patients who received IMRT report less decline in their QOL

An analysis of quality of life (QOL) data of stage III lung cancer patients who received higher doses of radiation therapy (with chemotherapy) shows a significantly lower quality of life at 3 months after treatment compared to patients who received a standard dose of radiation (with chemotherapy), according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.

24 Sep 2013

FDA approves revised labeling for Sapien Transcatheter Heart Valve

The U.S. Food and Drug Administration today approved revised labeling for the Sapien Transcatheter Heart Valve, making the device available to an expanded group of patients who have inoperable aortic valve stenosis, a disease of the heart valves that causes narrowing of the aortic valve, restricting blood flow from the heart.

24 Sep 2013

Marriage improves outcomes among patients with cancer, says oncologist

New results from a large retrospective study of the National Cancer Institute's SEER database show that patients with cancer who were married at the time of diagnosis live markedly longer compared to unmarried patients.

24 Sep 2013

Protecting stem cells around hippocampus in brain reduces rate of memory loss in cancer patients

Protecting the stem cells that reside in and around the hippocampus - a C-shaped area in the temporal lobe on both sides of the brain associated with the ability to form and store memories - substantially reduces the rate of cancer patients' memory loss during whole-brain radiotherapy without a significant risk of recurrence in that area of the brain, a new study shows.

24 Sep 2013

New diagnostic criteria for TSC appear in recent online issue of Pediatric Neurology

A paper detailing new diagnostic criteria for tuberous sclerosis complex (TSC) appears in the most recent online issue of Pediatric Neurology. The author is Hope Northrup, M.D., professor of pediatrics at The University of Texas Health Science Center at Houston (UTHealth).

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

Mild COPD phenotype discovery offers treatment hope

Research indicates that smokers with and without mild chronic obstructive pulmonary disease can be classified into distinct phenotypes on the basis of computed tomography findings.

23 Sep 2013

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

Novartis announced today that the European Commission approved once-daily Ultibro® Breezhaler® (indacaterol 85 mcg / glycopyrronium 43 mcg) as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD). In addition, the Japanese Ministry of Health, Labour and Welfare (MHLW) approved once-daily Ultibro® Inhalation Capsules (glycopyrronium 50 mcg / indacaterol 110 mcg), delivered through the Breezhaler® device, for relief of various symptoms due to airway obstruction in chronic obstructive pulmonary disease (COPD). Ultibro® Breezhaler® / Ultibro® Inhalation Capsules were developed under the name QVA149.

23 Sep 2013

Researchers lead two major trials to test potential treatments for asbestos-related cancer

University of Leicester researchers are leading two major trials into treatments for a type of cancer which affects those exposed to asbestos.

23 Sep 2013

Scientists one step closer to developing universal flu vaccine

Scientists have moved closer to developing a universal flu vaccine after using the 2009 pandemic as a natural experiment to study why some people seem to resist severe illness.

23 Sep 2013

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

The University of North Carolina at Chapel Hill received two separate grants from the U.S. Food and Drug Administration and the National Institutes of Health today as part of an on-going interagency partnership. UNC will house two of 14 Tobacco Centers of Regulatory Science, which are receiving a total of up to $53 million for tobacco-related research in fiscal year 2013.

21 Sep 2013

Mother who smoke during her pregnancy may transmit asthma to future generation

Asthma is a serious public health problem. An estimated 300 million people worldwide suffer from this sometimes deadly lung disease, a number expected to increase to 400 million by 2025. One well-established risk factor for asthma is having a mother who smoked during her pregnancy.

21 Sep 2013

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

Janssen Pharmaceuticals, Inc. announced today a newly published, pooled analysis of the Phase III EINSTEIN trial program, showing XARELTO (rivaroxaban) is as effective as the standard of care in reducing the risk of deep vein thrombosis and pulmonary embolism in people with symptomatic DVT or PE, while reducing the incidence of major bleeding by 46 percent.

21 Sep 2013

New research may help in regulation of tobacco products to protect public health

UC San Francisco will receive a five-year, $20 million grant as part of a first-of-its-kind tobacco science regulatory program by the U.S. Food and Drug Administration and the National Institutes of Health.

21 Sep 2013

Lungs News and Research

miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Metastatic site impacts survival in targeted RCC treatment

Changes in national diets linked to dramatic rise in AD prevalence in Japan and developing countries

Messages that warn consumers about potentially harmful side effects increase product sales

Depression in cancer patients who receive RT can be identified by 2-item questionnaire

ACR journals publish guide that provides new treatments for children with systemic JIA

Lung cancer patients who received IMRT report less decline in their QOL

FDA approves revised labeling for Sapien Transcatheter Heart Valve

Marriage improves outcomes among patients with cancer, says oncologist

Protecting stem cells around hippocampus in brain reduces rate of memory loss in cancer patients

New diagnostic criteria for TSC appear in recent online issue of Pediatric Neurology

Researchers discover drug that halts growth of brain tumor cells

Mild COPD phenotype discovery offers treatment hope

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

Researchers lead two major trials to test potential treatments for asbestos-related cancer

Scientists one step closer to developing universal flu vaccine

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

Mother who smoke during her pregnancy may transmit asthma to future generation

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

New research may help in regulation of tobacco products to protect public health

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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