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Molecular marker predicts longer survival among patients prescribed two cancer drugs

Johns Hopkins scientists have identified a molecular marker called "Mig 6" that appears to accurately predict longer survival -- up to two years -- among patients prescribed two of the most widely used drugs in a class of anticancer agents called EGFR inhibitors.

6 Sep 2013

Study: Less than 10 minutes of higher-intensity physical activity reduce risk of obesity

Short bursts of less than 10 minutes of higher-intensity physical activity reduce the risk of obesity, finds a new study in the American Journal of Health Promotion.

6 Sep 2013

CT screening proven effective for lung cancer

There is strong evidence to support the effectiveness of screening for lung cancer with low-dose computed tomography, a systematic review has found.

5 Sep 2013

Chemotherapy best second-line option for EGFR wild-type NSCLC

Chemotherapy is more effective than erlotinib as second-line therapy in people with advanced non-small-cell lung cancer and wild-type epidermal growth factor receptor genotype, a randomized controlled trial has found.

5 Sep 2013

Longer looks: Phenomenal growth of the Cleveland Clinic prompts hopes for the city; the bittersweet decision to donate organs

Delos M. "Toby" Cosgrove arrived at the Cleveland Clinic in 1975 as an "incredibly poor" 34-year-old dreaming of a life as a cardiac surgeon. … As the years passed he became well-known for pioneering the replacement of heart valves, eventually assuming the chair of the department of cardiothoracic surgery.

From Medtronic 5 Sep 2013

Study: Death risk is greatest for those who developed hypertrophic cardiomyopathy in childhood

A long-term study of children with a complex heart condition called hypertrophic cardiomyopathy (HCM) found that the risk of death or need for immediate listing for heart transplantation was greatest for those who developed this disease as infants with congestive heart failure and for children who also had selective inborn errors of metabolism, a group of rare genetic disorders in which one or more of the body's key metabolic processes are disrupted.

5 Sep 2013

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

A stressful pregnancy might be the last thing a future mother needs, but it is to her unborn baby that this stress spells real trouble. All because stress hormones (called glucocorticoids or GCs) can disturb normal foetal brain development, leading to behavioural and/or emotional problems later in life.

5 Sep 2013

ESMO recognises oncologists with prestigious awards

The European Society for Medical Oncology, the leading pan-European organisation representing medical oncology professionals, announced today the recipients of the annual society's prestigious awards, recognising excellence in oncology.

5 Sep 2013

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

In the Middle East and North Africa, heart disease, stroke, and diabetes are causing a massive amount of premature death and disability. People in Latin America and the Caribbean are living longer on the whole, yet they face increasing threats from chronic diseases. Mortality has declined in many South Asian countries, yet the number of deaths by non-communicable diseases and self-harm has skyrocketed since 1990.

5 Sep 2013

Worsening air pollution could increase annual premature deaths in 21st century

This century, climate change is expected to induce changes in air pollution, exposure to which could increase annual premature deaths by more than 100,000 adults worldwide.

5 Sep 2013

New influenza vaccine delivered via microneedle avoids pain and side effects

Scientists have developed an influenza vaccine delivered via microneedle patch that provided 100 percent protection against a lethal influenza virus in mice more than one year after vaccination. They report their findings in the September 2013 issue of the journal Clinical and Vaccine Immunology.

5 Sep 2013

Study shows benefit of chemotherapy on survival of elderly patients with SCLC

Although numerous randomized clinical trials have demonstrated a benefit of chemotherapy for patients with small-cell lung cancer (SCLC), these trials have predominantly compared different chemotherapy regimens rather than comparing chemotherapy to best supportive care. Some of them included chest radiation or prophylactic cranial irradiation. Moreover, many trials excluded elderly patients.

5 Sep 2013

Ontario researchers develop evidence-based recommendations for lung cancer screening

Lung cancer is the most common cause of cancer death in Ontario. Screening for lung cancer using low-dose computed tomography has been the subject of many research studies since the 1990s. The National Lung Screening Trial compared LDCT with chest radiograph in high-risk populations and found a 20 percent reduction in lung cancer mortality at 6 years with LDCT after an initial scan and two annual rounds of screening.

5 Sep 2013

Researchers find no difference in stage-adjusted lung cancer mortality between blacks and whites

According to the American Cancer Society, an estimated 160,340 lung cancer deaths occurred in the United States in 2012, accounting for 28 percent of all cancer deaths. While survival from lung cancer has improved since the early 1990s, racial differences in lung cancer survival persist such that blacks experience poorer 5-year survival for lung cancer compared to whites.

5 Sep 2013

Latest study recommends accelerated radiotherapy for un-resected NSCLC patients

Radiotherapy with or without chemotherapy is increasingly being used in the curative treatment for un-resected non-small cell lung cancer (NSCLC). But, until now, researchers had not looked at the cost-effectiveness of the treatment.

5 Sep 2013

People with CVD more likely to take preventive medicines when combined in one pill

People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association.

5 Sep 2013

Indicators of poor preoperative health predict risk of major medical complications

For older adults undergoing surgery for spinal stenosis, some simple indicators of poor preoperative health predict a high risk of major medical complications, reports a study in the September 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

4 Sep 2013

Researchers uncover evidence that Richard III had roundworm infection

Researchers based at the University of Cambridge and the University of Leicester have uncovered evidence that Richard III suffered from a roundworm (Ascaris lumbricoides) infection, according to a Clinical Picture published in The Lancet.

4 Sep 2013

US scientists identify risk factors for pediatric hypertrophic cardiomyopathy

US scientists have identified key risk factors that predict which children with hypertrophic cardiomyopathy, the most common cause of sudden death in young people, are at greatest risk of death or need for heart transplant—information that could help physicians figure out who will benefit most from transplant surgery.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Lungs News and Research

Molecular marker predicts longer survival among patients prescribed two cancer drugs

Study: Less than 10 minutes of higher-intensity physical activity reduce risk of obesity

CT screening proven effective for lung cancer

Chemotherapy best second-line option for EGFR wild-type NSCLC

Longer looks: Phenomenal growth of the Cleveland Clinic prompts hopes for the city; the bittersweet decision to donate organs

Study: Death risk is greatest for those who developed hypertrophic cardiomyopathy in childhood

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

ESMO recognises oncologists with prestigious awards

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

Worsening air pollution could increase annual premature deaths in 21st century

New influenza vaccine delivered via microneedle avoids pain and side effects

Study shows benefit of chemotherapy on survival of elderly patients with SCLC

Ontario researchers develop evidence-based recommendations for lung cancer screening

Researchers find no difference in stage-adjusted lung cancer mortality between blacks and whites

Latest study recommends accelerated radiotherapy for un-resected NSCLC patients

People with CVD more likely to take preventive medicines when combined in one pill

Indicators of poor preoperative health predict risk of major medical complications

Researchers uncover evidence that Richard III had roundworm infection

US scientists identify risk factors for pediatric hypertrophic cardiomyopathy

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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