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New mRNA-based malaria vaccine shows promise in preclinical trials

Trans-Tasman research collaborators from Te Herenga Waka-; Victoria University of Wellington's Ferrier Research Institute and the Malaghan Institute of Medical Research in New Zealand, and the Peter Doherty Institute for Infection and Immunity in Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasite Plasmodium in preclinical models.

20 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

Targeting the "don't eat me" signal may improve immunotherapy for glioblastoma

"Don't eat me!" That's how one might translate the signal that the cancer cells in a glioblastoma send to the macrophages (white blood cells specialized in removing dead and dying cellular matter) in the brain.

19 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

Immunomodulatory effects of PFAS can impair health

Because they are persistant, per- and polyfluoroalkyl substances (PFAS) are also known as "chemicals for eternety".

18 Jul 2023

Breast milk antibodies vary widely among mothers

Breast milk from each individual contains a unique assemblage of antibodies that are surprisingly stable throughout lactation and across pregnancies, according to a new Journal of Experimental Medicine study from the University of Pittsburgh School of Medicine.

18 Jul 2023

Babies have a 'secret weapon' that helps to fight new pathogens

A pair of new studies led by researchers at Columbia University explains why babies get so many common respiratory infections and identifies a specialized cluster of immune cells found only in babies that help them better cope with new pathogens.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research directed by Johns Hopkins investigators.

17 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Age and immunity: study highlights challenges and opportunities for vaccine protection

Scientists have evaluated molecular mechanisms responsible for heterogeneous responses to influenza vaccination among older adults.

17 Jul 2023

Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

Boosted immunity: Delta and Omicron-BA.1 infections enhance protection in vaccinated patients

Researchers examined the immune response and potential cross-protection in hospitalized patients with breakthrough infections.

17 Jul 2023

DFG funds new clinical research unit to study autoimmune-mediated neurological diseases

How do neurological disorders arise that are caused, triggered, or influenced by antibodies? What better possibilities are there for diagnosis – and above all for treatment? These are the questions addressed by the new Clinical Research Unit "BecauseY" headed by Charité – Universitätsmedizin Berlin. Innovative treatment options will especially benefit patients who at first glance are not suspected of having an antibody-mediated neurological disease.

14 Jul 2023

Antibodies: More than just a key-lock mechanism

Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with Covid-19.

14 Jul 2023

COVID antiviral treatments underused in nursing homes, study finds

Nursing homes were a key battleground during the COVID pandemic and prioritized for distribution of PPE, vaccines, and COVID testing kits.

14 Jul 2023

Australian researchers discover how COVID-19 can infect the human placenta

In a landmark study published in Nature Cell Biology, Australian researchers, led by Professor Jose Polo from Monash University and the University of Adelaide and University of Melbourne's Professor Kanta Subbarao from the Peter Doherty Institute for Infection and Immunity (Doherty Institute), have revealed how COVID-19 can infect the human placenta.

14 Jul 2023

UW Medicine surgeons saved a patient with dual-organ transplant

Doctors in Seattle are reporting a history-making case in which a patient received two donor organs, a liver and a heart, to prevent the extreme likelihood that her body would reject a donor heart transplanted alone.

14 Jul 2023

Antibodies News and Research

New mRNA-based malaria vaccine shows promise in preclinical trials

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

T cells can be used to identify type 1 diabetes risk, study shows

Targeting the "don't eat me" signal may improve immunotherapy for glioblastoma

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Immunomodulatory effects of PFAS can impair health

Breast milk antibodies vary widely among mothers

Babies have a 'secret weapon' that helps to fight new pathogens

Donanemab shows promise in slowing Alzheimer's disease

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Age and immunity: study highlights challenges and opportunities for vaccine protection

Breast cancer and MEN1: exploring the connection

Boosted immunity: Delta and Omicron-BA.1 infections enhance protection in vaccinated patients

DFG funds new clinical research unit to study autoimmune-mediated neurological diseases

Antibodies: More than just a key-lock mechanism

COVID antiviral treatments underused in nursing homes, study finds

Australian researchers discover how COVID-19 can infect the human placenta

UW Medicine surgeons saved a patient with dual-organ transplant

A new way of characterising biomolecules eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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