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CST introduces HER3 antibody for studying HER2-mediated breast, lung and ovarian tumors

Cell Signaling Technology, Inc. of Danvers, MA, announced today that it has introduced a highly specific HER3 rabbit monoclonal antibody (mAb), an important addition for researchers studying HER2-mediated breast, lung and ovarian tumors.

From Cell Signaling Technology 28 Aug 2013

Virttu Biologics treats first cohort of patients in SEPREHVIR Phase I/IIa study

Virttu Biologics Limited, a UK biotechnology company with expertise in the field of oncolytic viruses, has announced that it has treated the first cohort of patients in its Phase I/IIa clinical study of its oncolytic virus, SEPREHVIR (HSV1716) for the treatment of malignant pleural mesothelioma.

27 Aug 2013

Plymouth researcher receives award to develop lab-based mouse cell for research work

A researcher from Plymouth University Peninsula Schools of Medicine and Dentistry has received an award of - 94,365 (Sterling) from the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), for a pilot study to develop the lab-based creation of a type of mouse cell which could be used in place of the live animals for research related to infectious and allergic lung conditions.

27 Aug 2013

Wait times for colorectal cancer procedures at VA hospitals increase to 32 days

A study published in the August print issue of the Journal of Oncology Practice shows that from 1998-2008, wait times for colorectal cancer operations at Veterans Administration hospitals increased from 19 to 32 days. But researchers think longer waits may be a reflection of several unmeasured variables including more careful care, staffing, and patient conditions or preferences.

27 Aug 2013

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Each year, millions of people in the United States get a tuberculosis skin test to see if they have the infection that still affects one third of the world's population. But the standard diagnostic test is difficult to give, because a hypodermic needle must be inserted at a precise angle and depth in the arm to successfully check for tuberculosis.

27 Aug 2013

Researchers discover additional cystic fibrosis-causing mutations

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF.

26 Aug 2013

BESTCILIA project aims to improve screening, treatment of Primary Ciliary Dyskinesia

Primary Ciliary Dyskinesia is mainly a lung disease: a rare, genetically heterogeneous disorder resulting from dysfunction of small hair-like organelles (cilia) that clean the upper and lower airways. It can also affect multiple organs beside the respiratory system, and may cause serious impairment and lower quality of life. Its prevalence is estimated to be about 1 in 16,000.

26 Aug 2013

Researchers request all countries to record smoking on death registries

Researchers today [Friday 23 August] call for official death registries in all countries to record whether the dead person was a smoker, in a research Article published in The Lancet.

23 Aug 2013

No need of restricting women's food and fluid intake during labor, shows study

Despite the longstanding, widespread practice of restricting women's food and fluid intake during labor, a large-scale analysis in The Cochrane Library finds no need for these restrictions and supports women eating and drinking as they please.

23 Aug 2013

Scientists grow cells that line blood vessels from human iPSCs

In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels-called vascular endothelial cells-from human induced pluripotent stem cells (iPSCs), revealing new details about how these cells function.

23 Aug 2013

Moffitt Cancer Center study could offer hope to melanoma sufferers

A new study at Moffitt Cancer Center could offer hope to people with melanoma, the deadliest form of skin cancer. Researchers are investigating whether an injectable known as PV-10 can shrink tumors and reduce the spread of cancer.

23 Aug 2013

ATF3 gene may be the crucial link between stress and breast cancer: Study

In an unexpected finding, scientists have linked the activation of a stress gene in immune-system cells to the spread of breast cancer to other parts of the body.

23 Aug 2013

Drug to treat blood cancers may also stop spread of invasive breast cancer

A drug used to treat blood cancers may also stop the spread of invasive breast cancer, researchers at Mayo Clinic in Florida have discovered. Their study, published online in Breast Cancer Research, found that in the lab and in animals, the drug decitabine turns on a gene coding for protein kinase D1 (PRKD1) that halts the ability of cancer cells to separate from a tumor and spread to distant organs.

23 Aug 2013

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings could lead to better treatments to protect the kidney health of patients with the disease.

23 Aug 2013

Study confirms exposure to arsenic in drinking water can impair lung function

A new study confirms that exposure to low to moderate amounts of arsenic in drinking water can impair lung function. Doses of about 120 parts per billion of arsenic in well water-about 12 times the dose generally considered safe-produced lung damage comparable to decades of smoking tobacco. Smoking, especially by males, made arsenic-related damage even worse.

23 Aug 2013

Four simple steps increase chances of preoperative smoking cessation

A simple four-part program-including referral to a quit-smoking hotline and a free supply of nicotine patches-can increase the percentage of patients who quit smoking before undergoing surgery, reports a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

23 Aug 2013

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

A person's skin pigment, which determines hair color and skin tone, is influenced by the melanocortin-1 (MC1R) gene receptor. For the population's one to two percent of redheads, a mutation in MC1R accounts for their red hair color and typical light skin.

23 Aug 2013

Virtual 3-D heart model analyzes defibrillator placement in children born with heart defects

The small size and abnormal anatomy of children born with heart defects often force doctors to place lifesaving defibrillators entirely outside the heart, rather than partly inside — a less-than-ideal solution to dangerous heart rhythms that involves a degree of guesstimating and can compromise therapy.

22 Aug 2013

UC Davis Health System develops new screening strategy for lethal stage of TB in Asia

More than 20,000 people in Pakistan are being tested for the potentially deadly stage of tuberculosis using a new strategy developed at UC Davis Health System to effectively detect the disease in children for the first time.

22 Aug 2013

Almost 80% of air pollution comes from city traffic and other fossil-fuel combustion

Almost 80 percent of air pollution involving soot that spreads from China over large areas of East Asia - impacting human health and fostering global warming - comes from city traffic and other forms of fossil-fuel combustion, such as home cooking with coal briquettes.

22 Aug 2013

Lungs News and Research

CST introduces HER3 antibody for studying HER2-mediated breast, lung and ovarian tumors

Virttu Biologics treats first cohort of patients in SEPREHVIR Phase I/IIa study

Plymouth researcher receives award to develop lab-based mouse cell for research work

Wait times for colorectal cancer procedures at VA hospitals increase to 32 days

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Researchers discover additional cystic fibrosis-causing mutations

BESTCILIA project aims to improve screening, treatment of Primary Ciliary Dyskinesia

Researchers request all countries to record smoking on death registries

No need of restricting women's food and fluid intake during labor, shows study

Scientists grow cells that line blood vessels from human iPSCs

Moffitt Cancer Center study could offer hope to melanoma sufferers

ATF3 gene may be the crucial link between stress and breast cancer: Study

Drug to treat blood cancers may also stop spread of invasive breast cancer

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Study confirms exposure to arsenic in drinking water can impair lung function

Four simple steps increase chances of preoperative smoking cessation

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

Virtual 3-D heart model analyzes defibrillator placement in children born with heart defects

UC Davis Health System develops new screening strategy for lethal stage of TB in Asia

Almost 80% of air pollution comes from city traffic and other fossil-fuel combustion

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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