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Chemical compound prevents fungal cells from adhering to surfaces

Targeting serious and sometimes deadly fungal infections, a team of researchers at Worcester Polytechnic Institute (WPI) and the University of Massachusetts Medical School (UMMS) has discovered a chemical compound that prevents fungal cells from adhering to surfaces, which, typically, is the first step of the infection process used by the human pathogen Candida albicans (C. albicans).

14 Aug 2013

Strategy that dismantles flu viral genome in human lung cells ensures safe research

A new strategy that dismantles a viral genome in human lung cells will ensure safe research on deadly strains of influenza, say researchers from the Icahn School of Medicine at Mount Sinai.

13 Aug 2013

Harvard University receives grant to use organs-on-chips device to test human response to radiation

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has received a $5.6 million grant award from the United States Food and Drug Administration (FDA) to use its Organs-on-Chips technology for a novel application of keen interest to national security and health officials: to test human physiological responses to radiation, and to evaluate drugs designed to counter those effects.

13 Aug 2013

Saint Luke's Heart Institute seeks talented individuals for postdoctoral cardiovascular research

Saint Luke's Mid America Heart Institute—one of the leading outcomes research centers in the nation—is seeking highly motivated, talented individuals for its two-year postdoctoral training program in cardiovascular outcomes research.

12 Aug 2013

Study of childhood epilepsies links two new genes to severe forms of disease

A genetic study of childhood epilepsies has linked two new genes to severe forms of disease and provides a novel strategy for identifying therapy targets. This study used a cutting-edge genetic technique, called exome sequencing, to search for new mutations that are not inherited.

12 Aug 2013

Researchers identify biomarkers of TB that may help in new treatments

Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments.

12 Aug 2013

Four genetic variants in non-small cell lung cancer patients help predict survival, treatment response

Researchers at the Moffitt Cancer Center have identified four inherited genetic variants in non-small cell lung cancer patients that can help predict survival and treatment response. Their findings could help lead to more personalized treatment options and improved outcomes for patients.

9 Aug 2013

Robotic intubation device automatically identifies lungs and navigates toward it

Graduates of the Hebrew University's Biodesign program revealed a robotic intubation device that automatically identifies the lungs using an infrared source and navigates toward it.

9 Aug 2013

Journey Forward creates tool to help cancer survivors initiate care planning with health care providers

Journey Forward, a leader in Survivorship Care Planning, is moving forward patient-centered care by enhancing its suite of free, award-winning survivorship care planning tools with My Care Plan.

9 Aug 2013

KU researchers receives grant to create new program to help American Indian students stop smoking

The University of Kansas Cancer Center's Cancer Control and Population Health program got a boost in April when Won Choi, Ph.D., and his colleagues were awarded a $2.7 million, five-year NCI grant to create an Internet-based program to help American Indian tribal college students stop smoking.

8 Aug 2013

One-third of patients with heart pumps develop infection at abdominal power connection site

Cardiac surgeons and cardiologists at the University of Maryland Heart Center are part of a multi-center clinical trial evaluating the efficacy of powering heart pumps through a skull-based connector behind the ear. Typically, these devices for patients with severe heart failure are energized through an electrical cord connected at an abdominal site, where potentially deadly infections can develop.

8 Aug 2013

Ret enzyme may be a novel therapeutic target in selected groups of breast cancer patients

Scientists at the MedUni Vienna, in collaboration with a working group led by Nancy Hynes at the University of Basel, have discovered a new approach in the treatment of breast cancer: an international team involving the Clinical Institute of Pathology at the MedUni Vienna has been able to demonstrate the activation of a receptor, the Ret protein (Rearranged during transfection), on the surface of breast cancer cells. Increased levels of this protein are associated with a lower likelihood of survival for breast cancer patients.

8 Aug 2013

Research shows how mammalian and bacterial kingdoms interact

The bacteria Streptococcus pneumoniae harmlessly colonizes the mucous linings of throats and noses in most people, only becoming virulent when they leave those comfortable surroundings and enter the middle ears, lungs or bloodstream. Now, in research published in July in mBio, University at Buffalo researchers reveal how that happens.

8 Aug 2013

AmpliPhi releases data on phage therapy for treatment of lung infections in Cystic Fibrosis patients

AmpliPhi BioSciences Corp. (OTC: APHB) ("AmpliPhi"), the leader in the development of bacteriophage-based antibacterial therapies to treat drug resistant bacterial infections, yesterday presented data relating to the use of bacteriophages in the treatment of Pseudomonas aeruginosa (P. aeruginosa) at the 20th Biennial Evergreen International Phage Meeting held in Olympia, Washington, USA. P. aeruginosa is the major cause of lung infections in cystic fibrosis (CF) patients.

8 Aug 2013

Specific pattern in lung tumor pathology is strong predictor of recurrence, says study

A new study by thoracic surgeons and pathologists at Memorial Sloan-Kettering Cancer Center shows that a specific pattern found in the tumor pathology of some lung cancer patients is a strong predictor of recurrence.

8 Aug 2013

Chronic exposure biomass fuel smoke can cause cardiovascular problems

Rural households in developing countries often rely on burning biomass, such as wood, animal dung and waste from agricultural crops, to cook and heat their homes. The practice is long known to cause lung disease, but a new study from Washington University School of Medicine in St. Louis and Johns Hopkins University School of Medicine links the resulting smoke to cardiovascular problems, including an increase in artery-clogging plaques, artery thickness and higher blood pressure.

8 Aug 2013

Drinking two cups of hot chocolate a day may keep brains healthy

Drinking two cups of hot chocolate a day may help older people keep their brains healthy and their thinking skills sharp, according to a study published in the August 7, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

8 Aug 2013

DNA mutation 'signature' identified in urinary tract cancers linked to birthwort herb

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

8 Aug 2013

Study could boost development of personalised medicine in cancer care and therapy

A team of scientists led by Associate Professor Zeng Qi from A*STAR's Institute of Molecular and Cell Biology have discovered a new biomarker which will help physicians predict how well cancer patients respond to cancer drugs. Having the means to identify patients who are most likely to benefit from currently available cancer drugs not only reduces substantially the healthcare cost for the patient, it could mean saving precious lives by getting the right drugs to the right patient at the onset of the treatment.

7 Aug 2013

Exercise could reduce metabolic disease complications in patients post-transplantation

New research reveals that metabolic syndrome—risk factors that can lead to heart disease and/or stroke—is common in liver transplant recipients, with rates highest at one year following the procedure.

7 Aug 2013

Lungs News and Research

Chemical compound prevents fungal cells from adhering to surfaces

Strategy that dismantles flu viral genome in human lung cells ensures safe research

Harvard University receives grant to use organs-on-chips device to test human response to radiation

Saint Luke's Heart Institute seeks talented individuals for postdoctoral cardiovascular research

Study of childhood epilepsies links two new genes to severe forms of disease

Researchers identify biomarkers of TB that may help in new treatments

Four genetic variants in non-small cell lung cancer patients help predict survival, treatment response

Robotic intubation device automatically identifies lungs and navigates toward it

Journey Forward creates tool to help cancer survivors initiate care planning with health care providers

KU researchers receives grant to create new program to help American Indian students stop smoking

One-third of patients with heart pumps develop infection at abdominal power connection site

Ret enzyme may be a novel therapeutic target in selected groups of breast cancer patients

Research shows how mammalian and bacterial kingdoms interact

AmpliPhi releases data on phage therapy for treatment of lung infections in Cystic Fibrosis patients

Specific pattern in lung tumor pathology is strong predictor of recurrence, says study

Chronic exposure biomass fuel smoke can cause cardiovascular problems

Drinking two cups of hot chocolate a day may keep brains healthy

DNA mutation 'signature' identified in urinary tract cancers linked to birthwort herb

Study could boost development of personalised medicine in cancer care and therapy

Exercise could reduce metabolic disease complications in patients post-transplantation

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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