Lungs News and Research

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"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Bethesda, MD-Japanese researchers have made a new step toward understanding why-and how to stop-runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The FASEB Journal scientists show that two receptors of an inflammatory molecule, called "leukotriene B4," play opposing roles in turning inflammation on and off for allergic asthma and COPD.

2 Aug 2013

Researchers hope to exploit unique metabolic profile of cancer

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

2 Aug 2013

Deletion of a protein improves ability to fight bacteria in mice with CGD

Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes of Health study. CGD, a genetic disorder also found in people, is marked by recurrent, life-threatening infections. The study's findings appear online in The Journal of Clinical Investigation.

2 Aug 2013

Researchers identify new culprit that likely plays big role in severity of asthma

MD-A new culprit has been identified that likely plays a big role in the severity of asthma-a small protein chemokine called CCL26. These findings were published in the Journal of Leukocyte Biology and represent the first demonstration that CCL26 is a potent regulator of the migration of asthmatic eosinophils, commonly observed in asthmatic airways. Results from this discovery may lead to new drug targets for the treatment of asthma.

2 Aug 2013

Study: Ultrasound treatments may prevent acute kidney injury

Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that this simple and noninvasive therapy may be an effective precaution for patients at risk.

2 Aug 2013

State highlights: Experts cite 'serious' health care risks at Calif. prison; higher cigarette tax in Mass. prompts smuggling fears; psychiatric care payment plan in N.C.

Medical experts reporting to a federal court monitor say health care at the California state prison at Corcoran poses "an ongoing serious risk of harm to patients" that results in preventable deaths. The report, filed in federal court Monday, finds "serious patient care issues" within the general hospital at the prison, including life-threatening infections caused by unsanitary conditions, nurses who did not check vitals and doctors who repeatedly "cut and paste" the same patient notes (St. John, 7/30).

1 Aug 2013

ATS releases clinical practice guidelines on management of childhood ILD in infants

The American Thoracic Society has released new clinical practice guidelines on the classification, evaluation and management of childhood interstitial lung disease in infants.

1 Aug 2013

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Cambridge scientists have identified an 'on/off' switch in a type of cancer which typically occurs in the testes and ovaries called 'malignant germ cell tumours'. The research was published today, 01 August, in the journal Cancer Research.

1 Aug 2013

Researchers identify novel approach to enhance tissue repair and organ regeneration

Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions.

1 Aug 2013

University of Iowa study links bigger lungs with improved survival for transplant patients

When it comes to lung transplants, bigger may be better. That's the main finding from a University of Iowa study, which found that oversized lungs lead to improved survival following lung transplants, particularly among patients receiving double-lung transplants.

1 Aug 2013

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

Afatinib has a novel mode of action and data has shown that it offers a clinical benefit to patients with a specific type of lung cancer, which we are further investigating in the extensive LUX-Lung clinical trial programme.

1 Aug 2013

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Administering the drug rituximab once weekly for one month provides the same benefits as 18 months of daily immunosuppressive therapy in people with severe forms of vasculitis, or inflammation of the blood vessels, a study has found.

1 Aug 2013

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Scientists seeking to harness the healing power of a miniscule signaling molecule that plays a critical role in certain acute and chronic diseases have been awarded a Program Project Grant (PPG) of nearly $10 million by the National Heart, Lung and Blood Institute of the National Institutes of Health.

1 Aug 2013

RCLCF launches interactive Lung Cancer Smart Map

Lung cancer patients can now check they are getting the best care available after the launch of a new interactive online map.

31 Jul 2013

Task force recommends annual CT scans for high-risk smokers

The U.S. Preventive Services Task Force has recommended that high-risk current and former smokers get an annual CT Scan to look for cancer. If the draft recommendation becomes final, insurers will likely have to cover the scan at no co-pay cost to consumers.

31 Jul 2013

Inhalable gene therapy may restore function of crucial enzyme to reverse deadly PAH

The deadly condition known as pulmonary arterial hypertension (PAH), which afflicts up to 150,000 Americans each year, may be reversible by using an inhalable gene therapy, report an international team of researchers led by investigators at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

31 Jul 2013

First Edition: July 30, 2013

Today's headlines include a USA Today story reporting that personal health care costs rose in the 12 months ending in May at the slowest rate in the last 50 years -- a finding that makes the White House happy.

30 Jul 2013

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

With oral anticoagulant rivaroxaban set to be subsidised under the Pharmaceutical Benefits Scheme (PBS) for preventing stroke, NPS MedicineWise is urging people to talk to their doctor before stopping or making any changes to their anticoagulant medicines.

30 Jul 2013

METH use can make person more susceptible to fungal lung infection

Methamphetamine use can make a person more susceptible to the lung infection cryptococcosis, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

30 Jul 2013

Graduate student receives NIH fellowship of more than $90,000 to study e-cigarette use

Ever since e-cigarettes hit the market in 2004, they have been advertised as an aid for cigarette smoking cessation. The aerosols produced by e-cigarettes, however, have yet to be screened for potential health risks.

30 Jul 2013

Lungs News and Research

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Researchers hope to exploit unique metabolic profile of cancer

Deletion of a protein improves ability to fight bacteria in mice with CGD

Researchers identify new culprit that likely plays big role in severity of asthma

Study: Ultrasound treatments may prevent acute kidney injury

State highlights: Experts cite 'serious' health care risks at Calif. prison; higher cigarette tax in Mass. prompts smuggling fears; psychiatric care payment plan in N.C.

ATS releases clinical practice guidelines on management of childhood ILD in infants

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Researchers identify novel approach to enhance tissue repair and organ regeneration

University of Iowa study links bigger lungs with improved survival for transplant patients

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

RCLCF launches interactive Lung Cancer Smart Map

Task force recommends annual CT scans for high-risk smokers

Inhalable gene therapy may restore function of crucial enzyme to reverse deadly PAH

First Edition: July 30, 2013

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

METH use can make person more susceptible to fungal lung infection

Graduate student receives NIH fellowship of more than $90,000 to study e-cigarette use

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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