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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists aim to decipher language of DNA

Yes, DNA has its own language and scientists want to understand it to apply personalized therapeutic solutions based on the analysis of the individual's genomic biomarkers and their regulation.

24 Jan 2018

Enzyme inhibitor and chemotherapy combination regresses glioblastoma

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.

24 Jan 2018

Scientists elucidate surprising dual function of ceramide synthase

Scientists at the University of Bonn have clarified a surprising dual function of ceramide synthase. The enzyme not only catalyzes a central step of the production of vital lipids. It also has the ability to turn genes involved in lipid metabolism on or off. The study is being published in the renowned journal Cell Reports.

24 Jan 2018

Genome analysis reveals leprosy's origin and drug resistance

Leprosy is an infectious disease with gruesome symptoms. It damages the skin, peripheral nerves, the upper respiratory tract, and the eyes.

24 Jan 2018

Porvair Sciences to showcase microplate and chromatography products at Analytica 2018

Porvair Sciences has announced that it will showcase its latest microplate and chromatography products at the forthcoming Analytica 2018 exhibition in Munich, Germany.

From Porvair Sciences Limited 24 Jan 2018

BIST researchers develop new retinal prosthesis to address visual degeneration

A healthy retina contains photoreceptor cells that convert light changes into nerve impulses, which are then carried along the optic nerve to the brain, where they are decoded into images. Diseases such as retinitis pigmentosa cause the photoreceptor cells to stop functioning, while the rest of the eye remains healthy.

24 Jan 2018

Researchers use epigenetic signatures to advance diagnosis for neurodevelopmental disorders

Greenwood Genetic Center researchers in collaboration with scientists from Canada have identified unique epigenetic signatures for nine neurodevelopmental disorders lending to a better method of diagnosis for disorders with much clinical overlap.

23 Jan 2018

Personality changes occur early on during development of Alzheimer's disease, research finds

A key feature of Alzheimer's disease is memory loss and losing one's ability to think and make decisions (also called "cognitive ability"). Those changes can begin slowly, during a phase called "mild cognitive impairment" (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer's disease.

23 Jan 2018

Scientists identify molecular key that opens up compacted genome

News article describing the recent discovery of pax7, a protein which opens up compacted DNA for access by transcription factors.

23 Jan 2018

New family of FFPE reagent kits launched by Beckman Coulter Life Sciences

BCLS launched a family of FormaPure reagent kits for extracting nucleic acid often-challenginging formalin-fixed, paraffin-embedded tissues.

From Beckman Coulter Life Sciences - Automation and Genomics 23 Jan 2018

Combination chemotherapy increases survival in animal models of glioblastoma

A diagnosis of the brain cancer glioblastoma carries a dismal prognosis, with most patients dying within five years.

23 Jan 2018

Study offers way to predict onset of lung disease in children with cystic fibrosis

Cystic fibrosis (CF) shortens life by making the lungs prone to repeated bacterial infections and associated inflammation.

19 Jan 2018

DNA study sheds light on longstanding puzzle of cell division

Scientists have solved a longstanding puzzle of how cells are able to tightly package DNA to enable healthy cell division.

19 Jan 2018

Researchers develop single blood test that screens for 8 cancer types

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

19 Jan 2018

Study reveals key mechanism of how cancer metastasis happens

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center researchers.

19 Jan 2018

$500 cancer detection blood tests may soon become reality

According to latest breakthrough in research, a blood test to detect eight common cancers, even before their symptoms begin to appear, may become a reality soon. The study report appears in the latest issue of the journal Science and gives hope for early detection of these deadly diseases when it could still be treated more effectively.

18 Jan 2018

New precision medicine approach for metastatic pancreatic cancer

A three-year grant has been awarded to fund a phase 1b clinical trial of a precision medicine approach to treating metastatic pancreatic cancer.

18 Jan 2018

Modular gene enhancers may be suitable target in treatment of blood cancer

Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer.

18 Jan 2018

Study suggests movement as accurate method to diagnose neurodevelopmental disorders

A new study led by researchers at Indiana University and Rutgers University provides the strongest evidence yet that nearly imperceptible changes in how people move can be used to diagnose neurodevelopmental disorders, including autism.

18 Jan 2018

Study to test new precision medicine approach for metastatic pancreatic cancer

The Lustgarten Foundation has awarded Columbia University's Herbert Irving Comprehensive Cancer Center a three-year grant, as part of its Translational Clinical Program, to test a new precision medicine approach to the treatment of metastatic pancreatic cancer.

18 Jan 2018