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Mutation in a gene could play role in congenital heart disease, say researchers

A mutation in a gene crucial to normal heart development could play a role in some types of congenital heart disease-the most common birth defect in the U.S. The finding, from a team in The Research Institute at Nationwide Children's Hospital, could help narrow the search for genes that contribute to this defect, which affects as many as 40,000 newborns a year.

30 Jul 2013

ALCF honors oncologist with Lectureship Award for ground-breaking work on lung cancer research

The Bonnie J. Addario Lung Cancer Foundation (ALCF) honored Tony Mok, MD, with the 2013 Addario Lectureship Award for his continued ground-breaking work for lung cancer patients, doctors and caregivers around the world. Dr. Mok, of Chinese University of Hong Kong, received the award at the 14th International Lung Cancer Congress held on July 25 in Huntington Beach, California.

29 Jul 2013

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Reporters Peter Whoriskey and Dan Keating have opened Post readers' eyes to the fact that Medicare pays for physician services -; a $69.6 billion item in 2012 -; according to an arcane and little-known price list, over which doctors themselves exercise considerable and less-than-totally-transparent influence (7/24).

26 Jul 2013

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

Why do some innovations spread so swiftly and others so slowly? Consider the very different trajectories of surgical anesthesia and antiseptics. ... On October 16, 1846, at Massachusetts General Hospital, Morton administered his gas through an inhaler in the mouth of a young man undergoing the excision of a tumor in his jaw. ... By February, anesthesia had been used in almost all the capitals of Europe, and by June in most regions of the world.

26 Jul 2013

Alcohol Research Program at Loyola University receives four NIH grants totaling $3M dollars

The Alcohol Research Program at Loyola University Chicago Stritch School of Medicine recently received four research grants, totaling more than $3 million, from the National Institutes of Health.

26 Jul 2013

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Significant advances have taken place in the management of patients with advanced and metastatic non-small-cell lung cancer over the last 5 years. Traditionally, all advanced NSCLC patients were treated in a similar manner.

26 Jul 2013

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

Obesity increases health risks for many things. Researchers wanted to know the impact of obesity on outcomes of patients with advanced non-small cell lung cancer. In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that obese patients had superior outcomes early on in the study, but then experienced increased hazards.

26 Jul 2013

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Malignant mesothelioma is a rare asbestos-associated malignancy with limited therapeutic options. Despite advances in the treatment, the median survival remains 12 months from the time of diagnosis. Increased understanding of the molecular basis for the diverse signaling pathways involved in cancer progression should promote the discovery of novel biomarkers for early diagnosis and potentially lead to more effective therapeutic tools for the disease.

26 Jul 2013

FDA allows marketing of Xpert MTB/RIF Assay for treatment of TB

The U.S. Food and Drug Administration today allowed marketing of the Xpert MTB/RIF Assay, the first FDA-reviewed test that can simultaneously detect bacteria that cause tuberculosis and determine if the bacteria contain genetic markers that makes them resistant to rifampin, an important antibiotic for the treatment of TB.

26 Jul 2013

EKF Diagnostics introduces STAT-Site M ß-HB strip test for DKA assessment

EKF Diagnostics, the global in vitro diagnostics business, announces the worldwide launch of the new STAT-Site M ß-HB, following successful CE marking.

From EKF Diagnostics 25 Jul 2013

NIST scientists develop new standard reference material to enable hospitals calibrate CAT scanners

Scientists at the National Institute of Standards and Technology have developed a new standard reference material, the first such measurement tool to enable hospitals to link important tissue density measurements made by CAT scans to international standards.

25 Jul 2013

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Columbia University Medical Center (CUMC) scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs.

25 Jul 2013

Verastem's defactinib gets FDA orphan drug designation for treatment of mesothelioma

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced that lead cancer stem cell inhibitor, VS-6063 (defactinib), has received orphan drug designation from the U.S. Food and Drug Administration for use in the treatment of mesothelioma, a rare form of lung cancer.

24 Jul 2013

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Back in the early 1960s, just before chemotherapy really started to be used, only about 30% of children survived cancer. That was mainly because they had cancers that were amenable to surgery.

24 Jul 2013

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

Inovio Pharmaceuticals, Inc. announced today that in a preclinical study with two animal models, Inovio's hTERT (human telomerase reverse transcriptase) DNA cancer vaccine administered with Inovio's CELLECTRA adaptive electroporation delivery technology generated robust and broad immune responses, broke the immune system's tolerance to its self-antigens, induced T-cells with a tumor-killing function, and increased the rate of survival.

24 Jul 2013

UPCI research could provide roadmap for developing personalized therapies for breast cancer

More than 230,000 women will be diagnosed with breast cancer in the U.S. this year, a diagnosis that comes with treatment choices that can be overwhelming to patients and complex to their doctors. But what if there was only one treatment for your breast cancer? And what if it was based on your genetics and specific cancer type in the hope of maximizing its effectiveness?

24 Jul 2013

Study: Breathing oxygen during radiation therapy can delay tumor growth

A multidisciplinary team at UT Southwestern Medical Center has found that measuring the oxygenation of tumors can be a valuable tool in guiding radiation therapy, opening the door for personalized therapies that keep tumors in check with oxygen enhancement.

24 Jul 2013

Lungs News and Research

Mutation in a gene could play role in congenital heart disease, say researchers

ALCF honors oncologist with Lectureship Award for ground-breaking work on lung cancer research

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

Alcohol Research Program at Loyola University receives four NIH grants totaling $3M dollars

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

FDA allows marketing of Xpert MTB/RIF Assay for treatment of TB

EKF Diagnostics introduces STAT-Site M ß-HB strip test for DKA assessment

NIST scientists develop new standard reference material to enable hospitals calibrate CAT scanners

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Verastem's defactinib gets FDA orphan drug designation for treatment of mesothelioma

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

UPCI research could provide roadmap for developing personalized therapies for breast cancer

Study: Breathing oxygen during radiation therapy can delay tumor growth

Researchers develop PEDV rapid diagnostic test

Cepheid, American Lung Association partner to promote TB awareness in U.S.

Array BioPharma announces positive results from ARRY-502 Phase 2 trial for allergic asthma

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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