DNA News and Research

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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study reveals how dengue virus replicates without triggering the body's defenses

A new study reveals how dengue virus manages to reproduce itself in an infected person without triggering the body's normal defenses. Duke researchers report that dengue pulls off this hoax by co-opting a specialized structure within host cells for its own purposes, like a lazy roommate sneaking bits of his laundry into the communal wash.

11 Jan 2018

Unhealthy diet makes the body's defenses more aggressive in the long term

The immune system reacts similarly to a high fat and high-calorie diet as to a bacterial infection. This is shown by a recent study led by the University of Bonn.

11 Jan 2018

Novel partnership creates Europe's first antimicrobial nitrile gloves

Unigloves new Fortified single use gloves incorporate silver ion technology from BioCote, which has been scientifically proven to destroy 90% of harmful bacteria within just 15 minutes and 99.5% in only two hours.

11 Jan 2018

Patients with desmoplastic melanoma respond well to immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Study finds genetic variations linked to BMI and obesity risk

It's not just diet and physical activity; your genes also determine how easily you lose or gain weight. In a study published in the January issue of Nature Genetics, researchers at the Icahn School of Medicine at Mount Sinai and other institutions of the Genetic Investigation of Anthropometric Traits consortium found 13 genes that carry variations associated with body mass index.

10 Jan 2018

Stress accelerates development of pancreatic cancer, study shows

A new study shows that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers--commonly used medications that inhibit these hormones--were found to increase survival in a mouse model of the disease.

10 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

Biomedical, Biophysical and Biological Applications of AFM

An interview with Dr. Thomas Mueller, Director of Product Management at Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 10 Jan 2018

Unique reusable treatment effectively destroys cancer cells

Cancer cells can be destroyed more effectively and selectively with a unique new reusable treatment, activated with a substance found in stinging nettles and ants - thanks to new research by the University of Warwick.

10 Jan 2018

New discovery could help treat breast cancer through precision medicine

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

9 Jan 2018

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

A new blood stabilization method, developed at the Massachusetts General Hospital Center for Engineering in Medicine, significantly prolongs the lifespan of blood samples for microfluidic sorting and transcriptome profiling of rare circulating tumor cells (CTCs), living cancer cells carried in the bloodstream.

9 Jan 2018

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

By the end of 2019, Regeneron plans to sequence the exomes of all 500,000 people within the UK Biobank resource, all with associated health records, creating an unprecedented resource linking human genetic variations to human biology and disease.

9 Jan 2018

Identical twins share additional level of molecular similarity

An international group of researchers has discovered a new phenomenon that occurs in identical twins: independent of their identical genes, they share an additional level of molecular similarity that influences their biological characteristics.

9 Jan 2018

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Patients with an aggressive form of leukemia, currently ineligible for any type of targeted therapy, may in fact benefit from some of these new drugs, according to new research by Queen Mary University of London.

9 Jan 2018

Deciphering Antibodies with Next-Generation Protein Sequencing Technology

Mr. Mingjie Xie, MSc, MBA, is the co-founder and CEO of Rapid Novor Inc. He is a computer scientist by training andreceived his MSc degree from Western University in the field of bioinformatics. He received his MBA degree from Richard Ivey School of Business to pursue his interests in business. Prior to co-founding Rapid Novor Inc, Mingjie is the COO of a bioinformatics software company.

From Rapid Novor Inc 9 Jan 2018

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Amity Manning, assistant professor of biology and biotechnology, has received a three-year, $300,000 award from the Smith Family Awards Program for Excellence in Biomedical Research.

8 Jan 2018

Study finds a cellular mechanism that protects plant genes from impacts of mutation

According to a new study conducted at the University of Oxford, a cellular mechanism termed DNA mismatch repair (MMR), preferentially protects plant genes from the damaging impacts of mutation.

8 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

DNA News and Research

Further Reading

Study reveals how dengue virus replicates without triggering the body's defenses

Unhealthy diet makes the body's defenses more aggressive in the long term

Novel partnership creates Europe's first antimicrobial nitrile gloves

Patients with desmoplastic melanoma respond well to immunotherapy

Company-sponsored CRISPR clinical studies to begin in 2018

Study finds genetic variations linked to BMI and obesity risk

Stress accelerates development of pancreatic cancer, study shows

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Biomedical, Biophysical and Biological Applications of AFM

Unique reusable treatment effectively destroys cancer cells

New discovery could help treat breast cancer through precision medicine

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

Identical twins share additional level of molecular similarity

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Deciphering Antibodies with Next-Generation Protein Sequencing Technology

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Study finds a cellular mechanism that protects plant genes from impacts of mutation

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Newly described super-silenced DNA reveals novel approach to reprogram cells

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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