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Comprehensive analysis of disease burden in US

In nearly every major cause of premature death - from ischemic heart disease to diabetes to interpersonal violence - the United States trails its economic peers, according to new research from a global collaborative of scientists led by the Institute for Health Metrics and Evaluation at the University of Washington.

12 Jul 2013

Infant vaccination against pneumonia helps protect elderly

Children who receive a vaccine to prevent blood and ear infections, appear to be reducing the spread of pneumonia to the rest of the population, especially their grandparents and other older adults.

11 Jul 2013

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

New insights into why obese cigarette smokers experience a high risk of heart disease suggest that cigarette smoke affects the activity of hundreds of key genes that both protect the heart and lungs and expose them to damage.

11 Jul 2013

Prolonged exposure to low levels of air pollution boosts lung cancer risk

Prolonged exposure to particulate air pollution increases the risk of lung cancer (particularly adenocarcinoma) even at levels below the European Union limit values, according to one of the largest studies of its kind published in The Lancet Oncology.

11 Jul 2013

Study identifies new groups of people at risk of parasitic lung infection

A study conducted by Dr. James Diaz, Professor of Public Health and Preventive Medicine and Program Director of the Environmental/Occupational Health Sciences Program at the LSU Health Sciences Center New Orleans School of Public Health, analyzed cases of a parasitic lung infection and found new modes of transmission and associated behaviors, identifying new groups of people at risk.

11 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

Innovative vaccine could offer hope to patients with advanced ovarian cancer

Loyola University Medical Center is conducting a clinical trial of an innovative vaccine that could offer hope to patients with advanced ovarian cancer.

10 Jul 2013

TGA of Australia approves Vertex Pharmaceuticals' KALYDECO for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced that the Therapeutic Goods Administration of Australia has approved KALYDECO (ivacaftor) for people with cystic fibrosis ages 6 and older who have at least one copy of the G551D mutation in the cystic fibrosis transmembrane conductance regulator gene.

10 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Low vitamin D blood levels are linked to greater risk of heart disease in whites and Chinese, but not in blacks and Hispanics, according to a study appearing this week in JAMA, a journal published by the American Medical Association.

10 Jul 2013

Key metabolites in blood could provide clues to long-term overall health and ageing

Scientists have found that key metabolites in blood - chemical 'fingerprints' left behind as a result of early molecular changes before birth or in infancy - could provide clues to a person's long-term overall health and rate of ageing in later life.

9 Jul 2013

Cancer immunotherapies promise to be a new tool in fight against cancer

Drugs that direct a cancer patient's immune system to eradicate her or his disease, known as cancer immunotherapies, promise to be a new tool in the fight against cancer. Since the Koch Institute's inception, exploring the close relationship between the immune system and cancer has been one of the Institute's priority research areas.

9 Jul 2013

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

9 Jul 2013

A few clinics are focused on helping pregnant women with prescription drug addictions

The Wall Street Journal examines the growing number of women addicted to pain killers and efforts to help them through pregnancies.

9 Jul 2013

Researcher receives $1.58M NIDCR grant to advance research on link between oral bacteria and fetal death

A new four-year, $1.58 million grant from the National Institute of Dental and Craniofacial Research, will allow a Case Western Reserve University School of Dental Medicine researcher to advance her work linking oral bacteria to fetal death.

9 Jul 2013

Researchers develop new PET tracer to better monitor the progress of cancer and cancer therapy

Imaging techniques in cancer medicine provide far more than merely information on the scale and location of cancerous ulcers. There are modern methods that additionally characterise the tumour cells precisely, for instance by specific molecules they carry on their surface. Such additional information gives doctors key clues as to the precise cancer type and enables them to predict the probability that a patient will respond to a particular form of therapy.

6 Jul 2013

Saint Luke's Hospital opens Charles & Barbara Duboc Cardio Health & Wellness Center

The Charles & Barbara Duboc Cardio Health & Wellness Center is ushering in a new era for preventive cardiac care at Saint Luke's Hospital.

6 Jul 2013

Scientists focus on the role of mutated adult neural stem cells play in human diseases

CHARGE syndrome* is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the broad spectrum of characteristic CHARGE symptoms has been a mystery.

6 Jul 2013

Immune response to TB bacterium varies between patients of different ethnic origin

The immune response to the bacterium that causes tuberculosis (TB) varies between patients of different ethnic origin, raising important implications for the development of tests to diagnose and monitor treatment for the disease, according to new research published today in the journal PLOS Pathogens.

5 Jul 2013

Findings uncover epigenomic modification that occurs during brain formation

Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline.

5 Jul 2013

Lungs News and Research

Comprehensive analysis of disease burden in US

Infant vaccination against pneumonia helps protect elderly

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

Prolonged exposure to low levels of air pollution boosts lung cancer risk

Study identifies new groups of people at risk of parasitic lung infection

New approach delivers RNA drugs to silence malfunctioning genes

Innovative vaccine could offer hope to patients with advanced ovarian cancer

TGA of Australia approves Vertex Pharmaceuticals' KALYDECO for cystic fibrosis

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Key metabolites in blood could provide clues to long-term overall health and ageing

Cancer immunotherapies promise to be a new tool in fight against cancer

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

A few clinics are focused on helping pregnant women with prescription drug addictions

Researcher receives $1.58M NIDCR grant to advance research on link between oral bacteria and fetal death

Researchers develop new PET tracer to better monitor the progress of cancer and cancer therapy

Saint Luke's Hospital opens Charles & Barbara Duboc Cardio Health & Wellness Center

Scientists focus on the role of mutated adult neural stem cells play in human diseases

Immune response to TB bacterium varies between patients of different ethnic origin

Findings uncover epigenomic modification that occurs during brain formation

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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