Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Two researchers from Bielefeld University receive ERC Starting Grants

The European Research Council has awarded ERC Starting Grants to two researchers from Bielefeld University.

5 Sep 2020

Research provides a map of coronavirus entry factors across the human body

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases and Cornell University in the US have investigated cellular factors that could be significant for an infection.

3 Sep 2020

Researchers develop new model to predict survival in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer among women and men in the USA, and recent studies have shown an increasing incidence in less developed regions, including Sub-Saharan Africa (SSA).

3 Sep 2020

Study shows what happens in the fetal brain affected by congenital Zika syndrome

Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly.

3 Sep 2020

Genomic analysis of specific E. coli strain can help develop potential vaccines

Foodborne pathogens are very common and usually benign, but certain virulent strains of pathogens can result in severe disease and even death.

3 Sep 2020

New EU research project seeks to kickstart the development of "Organoid Cell Atlas"

HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology.

31 Aug 2020

T cell epitopes from recovered COVID-19 patients identified for vaccine

A new study by researchers at The Hong Kong University of Science and Technology and published on the preprint server bioRxiv in August 2020 collates the available database of SARS-CoV-2 T cell epitopes gathered from 8 studies of COVID-19 patients who recovered. This could serve as a launchpad to fill in knowledge gaps regarding the immunological aspects of this disease, and drive towards an effective T cell vaccine.

31 Aug 2020

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

A study of a gateway receptor for SARS-CoV-2 led by Walter Lukiw, PhD, Professor of Neuroscience, Neurology and Ophthalmology at LSU Health New Orleans' Neuroscience Center of Excellence and School of Medicine, may help explain the wide variety of symptoms and organs involved with SARS-CoV-2 infection and COVID-19.

28 Aug 2020

AI algorithm promises to accurately diagnose Alzheimer's

By detecting subtle differences in the way that Alzheimer's sufferers use language, researchers at Stevens Institute of Technology have developed an A.I. algorithm that promises to accurately diagnose Alzheimer's without the need for expensive scans or in-person testing.

27 Aug 2020

New sequencing approach can detect rare mutation in large number of cells

A sequencing approach can home in on a rare mutation within a large number of cells, revealing implications for CRISPR genome editing and early cancer detection.

27 Aug 2020

University of Illinois to head two of artificial intelligence institutes in the U.S

The National Science Foundation and the U.S. Department of Agriculture's National Institute of Food and Agriculture are announcing an investment of more than $140 million to establish seven artificial intelligence institutes in the U.S. Two of the seven will be led by teams at the University of Illinois, Urbana-Champaign.

27 Aug 2020

Study tracks the mutation rate of SARS-Cov-2 virus

Since COVID-19 began its menacing march across Wuhan, China, in December 2019, and then across the world, the SARS-CoV-2 virus has taken a "whatever works" strategy to ensure its replication and spread.

25 Aug 2020

Re-designed natural enzyme could reverse nerve damage caused by stroke, spinal cord injury

A team of researchers from University of Toronto Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury.

25 Aug 2020

Loss of supporting cells in olfactory epithelium causes loss of smell in COVID-19

In the current pandemic of COVID-19, many patients have reported symptoms of loss of smell and taste. The cellular basis of this phenomenon has not been satisfactorily explained so far. However, a new study published in the Briefings in Bioinformatics in August 2020 shows how this symptom is related to viral pathogenesis.

23 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

Bioinformatics identifies key genes and cellular pathways in COVID-19

The COVID-19 pandemic is showing no signs of waning or extinction anytime soon. Now, a new study published on the preprint server bioRxiv* in August 2020 shows a new bioinformatics approach to studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics. This will help develop better therapies to counter the effects of these genes.

20 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

17 Aug 2020

Standardized guidelines for phage therapy can speed up lifesaving treatment

When clinicians resort to phage therapy for patients who don't respond to antibiotics, the patients are usually very ill and time is of the essence. But the average time for labs to produce therapeutic phages is more than a month.

17 Aug 2020

Bioinformatics News and Research

Further Reading

Two researchers from Bielefeld University receive ERC Starting Grants

Research provides a map of coronavirus entry factors across the human body

Researchers develop new model to predict survival in colorectal cancer

Study shows what happens in the fetal brain affected by congenital Zika syndrome

Genomic analysis of specific E. coli strain can help develop potential vaccines

New EU research project seeks to kickstart the development of "Organoid Cell Atlas"

T cell epitopes from recovered COVID-19 patients identified for vaccine

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

AI algorithm promises to accurately diagnose Alzheimer's

New sequencing approach can detect rare mutation in large number of cells

University of Illinois to head two of artificial intelligence institutes in the U.S

Study tracks the mutation rate of SARS-Cov-2 virus

Re-designed natural enzyme could reverse nerve damage caused by stroke, spinal cord injury

Loss of supporting cells in olfactory epithelium causes loss of smell in COVID-19

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Bioinformatics identifies key genes and cellular pathways in COVID-19

Study sheds light on 500-year old mystery about the human heart

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Standardized guidelines for phage therapy can speed up lifesaving treatment

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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