DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

A group of the nation's premier cancer researchers led by the Baylor Scott & White Research Institute and the Translational Genomics Research Institute -- has secured a $5.13 million federal grant to develop an early detection system for pancreatic cancer, the nation's third-leading cause of cancer-related death.

11 Dec 2017

Russian researchers create new approaches to prevention and treatment of diabetes

A team of scientists from the Ural Federal University and the Institute of Immunology and Physiology modeled type 1 diabetes in an experiment to study recovery processes in the pancreas.

11 Dec 2017

Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

Simple molecular test may help predict presence of high-grade pancreatic cancers

A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.

8 Dec 2017

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

8 Dec 2017

MIT researchers discover new way to make bacteria vulnerable to existing antibiotics

MIT researchers have discovered a way to make bacteria more vulnerable to a class of antibiotics known as quinolones, which include ciprofloxacin and are often used to treat infections such as Escherichia coli and Staphylococcus aureus.

8 Dec 2017

Research brings scientists one step closer to understanding development of ALS

University of Michigan-led research brings scientists one step closer to understanding the development of neurodegenerative disorders such as ALS.

8 Dec 2017

Parental lifespan genes could pave way for new therapeutic targets to prolong life

A large-scale international study led by the University of Exeter Medical School has discovered new genes linked to parents' lifespan - which could one day be targeted to help prolong human life.

8 Dec 2017

Large-scale study expands number of genetic markers linked to exceptional longevity

A new large-scale international study expands the number of genetic markers now known to be associated with exceptional longevity.

7 Dec 2017

Malaria parasite employs active strategy to deceive the immune system

Global efforts to eradicate malaria are crucially dependent on scientists' ability to outsmart the malaria parasite. And Plasmodium falciparum is notoriously clever: It is quick to develop resistance against medications and has such a complex life cycle that blocking it effectively with a vaccine has thus far proved elusive.

7 Dec 2017

Quick Automated DNA Purification offered with the Promega Maxwell® RSC PureFood Pathogen Kit

Maxwell® RSC PureFood Pathogen Kit offers food safety labs an easy and consistent automated DNA purification method for PCR-based testing of food pathogens.

From Promega Corporation 7 Dec 2017

TUM scientists build virus-sized structures using DNA origami technology

It is the double strands of our genes that make them so strong. Using a technique known as DNA origami, biophysicist Hendrik Dietz has been building nanometer-scale objects for several years at the Technical University of Munich.

7 Dec 2017

Brazilian researchers identify genes linked to melanoma progression

When researchers at the University of São Paulo in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric its orange color, they identified genes with altered expression in potentially invasive tumors and malignant cells resistant to chemotherapy.

6 Dec 2017

New compound targets APOE gene to reduce Alzheimer's damage in mice

People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease.

6 Dec 2017

Study shows how interplay between two key enzymes promotes brain tumor growth

Study results revealed previously unknown interplay between two key enzymes and a novel understanding of how brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Dec 2017

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1.

6 Dec 2017

Harvard scientists discover hundreds of genetic switches that influence height

It's been understood for decades that a host of factors - everything from pre- and post-natal health, nutrition, and genetics - play a role in determining height, but efforts to untangle the complex web of factors that contribute to height have long been stymied.

6 Dec 2017

DNA News and Research

Further Reading

Researchers find new role for SHARPIN protein in melanoma growth

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

Russian researchers create new approaches to prevention and treatment of diabetes

Scientists develop software that predicts leukemia-specific immune targets

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Simple molecular test may help predict presence of high-grade pancreatic cancers

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

MIT researchers discover new way to make bacteria vulnerable to existing antibiotics

Research brings scientists one step closer to understanding development of ALS

Parental lifespan genes could pave way for new therapeutic targets to prolong life

Large-scale study expands number of genetic markers linked to exceptional longevity

Malaria parasite employs active strategy to deceive the immune system

Quick Automated DNA Purification offered with the Promega Maxwell® RSC PureFood Pathogen Kit

TUM scientists build virus-sized structures using DNA origami technology

Brazilian researchers identify genes linked to melanoma progression

New compound targets APOE gene to reduce Alzheimer's damage in mice

Study shows how interplay between two key enzymes promotes brain tumor growth

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Harvard scientists discover hundreds of genetic switches that influence height

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest Life Science News