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Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Researchers discover new structures on the surface of living B cells for the first time

Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly the function of their antigen receptors.

11 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

Medicare policy change may lead to increased inequities in access to heart transplants

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a Michigan Medicine study finds.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), ringlike peripheral high iodine concentration maps from dual-energy CT (DECT) can help guide management in patients with known lung cancer and an indeterminate solitary nodule.

11 Jan 2023

Free questionnaire found to be reliable and valid for evaluating autism symptoms

Investigators have developed a freely available measure of autism symptoms that can help to screen for autism and monitor changes over time in symptoms.

11 Jan 2023

UC research could lead to possible treatments for scoliosis in the future

How cells shape complex tissues and organs during embryo development, which makes us what we are, has many mysteries.

11 Jan 2023

Study may help explain how excess weight can contribute to diabetes

People who are overweight or obese have a significantly increased risk of developing diabetes, but exactly how that happens is not well understood.

11 Jan 2023

Three genes found to be directly associated with cleft lip and palate

Researchers are finding more genes directly associated with cleft lip and palate.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Visual food cues can affect eating behavior even when you are not aware

Controlling your food intake can be even more difficult than you think. Osaka Metropolitan University scientists show that visual food cues can affect your eating behavior even when you are not aware of them.

11 Jan 2023

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

In this interview, News Medical speaks to Assitant Professor Ryan Jackson about his latest work, published in tandem Nature papers, detailing the discovery of a new CRISPR immune system.

11 Jan 2023

The decision of where to seek care is complicated by the multitude of options

One evening in February 2017, Sarah Dudley's husband, Joseph, started to feel sick. He had a high fever, his head and body ached, and he seemed disoriented, she said. The Dudleys had a decision to make: go to the hospital emergency room or to an urgent care clinic near their home in Des Moines, Iowa.

11 Jan 2023

New analysis improves the scientific community's understanding of COVID-19 immunity

A new analysis by Cedars-Sinai investigators is furthering the scientific community's understanding of COVID-19 immunity by showing that similar levels of COVID-19 antibodies are reached over an extended period of time in different population groups.

11 Jan 2023

RNAs may be a promising biomarker and therapeutic target for ischemic stroke

RUDN doctors analyzed the latest research on the use of RNA for the treatment and diagnosis of ischemic stroke.

10 Jan 2023

UC researcher focuses on studying how gene mutations help pancreatic cancer grow

Only about 11% of people will survive five years after the detection of advanced pancreatic cancer. Such a low rate of success in treating pancreatic cancer is due to its late detection and an incomplete understanding of the disease development processes.

10 Jan 2023

Medicine News and Research

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Researchers discover new structures on the surface of living B cells for the first time

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

Medicare policy change may lead to increased inequities in access to heart transplants

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

Free questionnaire found to be reliable and valid for evaluating autism symptoms

UC research could lead to possible treatments for scoliosis in the future

Study may help explain how excess weight can contribute to diabetes

Three genes found to be directly associated with cleft lip and palate

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Visual food cues can affect eating behavior even when you are not aware

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

The decision of where to seek care is complicated by the multitude of options

New analysis improves the scientific community's understanding of COVID-19 immunity

RNAs may be a promising biomarker and therapeutic target for ischemic stroke

UC researcher focuses on studying how gene mutations help pancreatic cancer grow

Injectable hydrogel suppresses infections and promotes healing around prosthetics

School garden-based interventions can improve metabolic parameters in children

Yale researchers identify neuronal basis of impaired consciousness in children with absence epilepsy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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