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Antipsychotic compound bifeprunox worth USD 1 billion per year to Solvay and Wyeth

Solvay has re-evaluated the commercial potential of bifeprunox, a Solvay compound in clinical development for the treatment of schizophrenia . Bifeprunox additionally has the potential to be developed in other disorders, i.e. bipolar disorder.

3 Jun 2004

Malaria, Africa's biggest killer

It's Africa's biggest killer, but it's not HIV. It causes economic losses of US$12 billion per year, but it's not a war. And it has slowed African economic growth by around 1.3 per cent per annum, but it’s not a famine.

2 Jun 2004

Gene linked to alcoholism

Alcoholism tends to run in families, suggesting that addiction, at least in part, has an underlying genetic cause. Now, researchers at the University of Illinois at Chicago have discovered a gene linked to alcohol dependency.

1 Jun 2004

Fighting in the eastern Democratic Republic of Congo will affect HIV patients

Fighting in the eastern Democratic Republic of Congo (DRC) town of Bukavu - adjacent to the border with Rwanda - near the end of May has caused an MSF team there to seek refuge in the nearby UN compound.

1 Jun 2004

Alcoholism tends to run in families, suggesting that addiction may be related to genetics

The gene the researchers investigated manufactures a protein called CREB, or cyclic AMP responsive element binding protein, which is known to regulate brain function during development and learning.

27 May 2004

New company is developing advanced therapeutics for stroke victims

Arizona Engineered Therapeutics Inc., a new company based on the research of three Arizona State University professors, is moving its first drug candidate closer to clinical trials.

26 May 2004

Discovery of gene linked to alcohol dependency

26 May 2004

3 or 4 glasses of wine a week can kill cancer cells

It’s well known that drinking red wine in moderation can have some health benefits, mainly attributed to a compound called resveratrol. Now, scientists at the University of Virginia Health System have discovered how.

25 May 2004

Zengen announces positive results of treatment for vaginal yeast infection

Zengen Inc. announced today positive phase I/II results for its proprietary molecule CZEN-002 for the treatment of vulvovaginal candidiasis (VVC), commonly known as vaginal yeast infection.

25 May 2004

Research suggests a connection between drinking tea regularly and a variety of potential health benefits

Today, iced tea continues to be one of the country's most beloved beverages, especially among those looking for a refreshing antioxidant boost. Drinking a tall glass of iced tea may offer more than just a thirst quencher.

25 May 2004

Antioxidant compound found in green tea leaves does not clear established plaque

Using a technique that enables them to study both early and advanced stages of arterial plaque buildup in the same mice, researchers at Cedars-Sinai Medical Center found that an antioxidant compound found in green tea leaves does not clear established plaque but does inhibit the development of new deposits.

24 May 2004

Compound Cilantro found in salsa kills harmful Salmonella bacteria

Researchers have identified a compound in cilantro, a key flavor component of salsa and a variety of other dishes, that kills harmful Salmonella bacteria and shows promise as a safe, natural food additive that could help prevent foodborne illness, according to a joint study by U.S. and Mexican researchers.

24 May 2004

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

Vertex Pharmaceuticals Incorporated has announced that it has expanded its drug discovery and development collaboration with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation.

24 May 2004

Accurate and effective new methods for diagnosis of Inflammatory bowel diseases

Inflammatory bowel diseases collectively cause significant lifestyle sacrifices and suffering and millions of dollars in related health care costs every year, partially due to a lack of effective diagnostic procedures and therapies. In new studies presented today at Digestive Disease Week in New Orleans, researchers show evidence of accurate and effective new methods for diagnosis, as well as improved treatment options, for sufferers of ulcerative colitis and Crohn’s diseases.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

A new synthetic chemical may provide framework for future drugs to treat brain-based ailments

A new synthetic chemical may provide the framework for future drugs that can treat a variety of brain-based ailments, ranging from overeating and drug dependency to neuropathic pain.

19 May 2004

Pharmaceutical agreement involving novel obesity compound

Bristol-Myers Squibb Company and Solvay Pharmaceuticals today announced that the companies have entered into a worldwide agreement for the Solvay compound SLV319, which is currently in Phase I development with potential for use in treating obesity and other metabolic disorders.

17 May 2004

Scientists have identified a compound that halts the activity of a deadly toxin called anthrax

University of Chicago scientists have identified a compound that halts the activity of a deadly toxin called anthrax lethal factor in laboratory tests. Nature Biotechnology will publish the findings online on May 16 and in the June issue of the journal's print edition.

17 May 2004

Researcher has learned how to maximize the cancer-fighting power of broccoli

University of Illinois researcher Elizabeth Jeffery has learned how to maximize the cancer-fighting power of broccoli. It involves heating broccoli just enough to eliminate a sulfur-grabbing protein, but not enough to stop the plant from releasing an important cancer-fighting compound called sulforaphane.

15 May 2004

Vitamin discovery offers clues for cancer chemotherapy

NH-Dartmouth Medical School cancer researchers, in a fusion of biochemistry and genetics, have discovered a new vitamin in a molecular pathway central to such vital processes as gene regulation, metabolism and aging. And, they found that milk contains this nutrient.

15 May 2004