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Johns Hopkins experts create clinical guidebook for convalescent plasma therapy

A team of Johns Hopkins experts has created a clinical guidebook to help hospitals and medical centers rapidly scale up their ability to deliver so-called convalescent plasma therapy, which leverages immune system components found in the plasma portion of blood from people who have recovered from COVID-19 illness.

14 Apr 2020

Researchers develop synthetic scaffolds for tendon and ligament regeneration

Australia's love of sport means it has one of the highest rates of knee anterior cruciate ligament (ACL) injury and reconstruction in the world.

14 Apr 2020

Experimental drug could stop tumor relapse, mice study shows

A drug that is well-tolerated in patients and prevents cancer coming back in mice has been identified by researchers at the Francis Crick Institute.

14 Apr 2020

Predicting the evolution of genetic mutations

Biologists have developed an algorithm able to predict how genetic mutations can make critical proteins change with evolution.

14 Apr 2020

Mutated ATP1B gene a risk factor for Parkinson’s

The brain consists of about 100 billion neurons that form a complex and interconnected network in our brain, allowing us to generate complex thought patterns and actions. These neurons or nerve cells are the functional units of the nervous system that process and transmit information around the body. Neurodegenerative diseases develop with the progressive loss of these neurons.

14 Apr 2020

OSU Superfund Research Program receives $12.7 million grant to assess toxicity of PAHs

An Oregon State University-led research program has been awarded a $12.7 million grant to serve the Pacific Northwest by studying harmful chemicals found at federally designated hazardous waste sites.

13 Apr 2020

New 3D imaging technique helps researchers watch neural activity in real time

Our ability to study networks within the nervous system has been limited by the tools available to observe large volumes of cells at once.

13 Apr 2020

Reprimo gene may play a role in menopause-related weight gain

A new study published in the journal Nature Metabolism in April 2020 indicates that some genes could allow women in menopause to remain healthy without hormone replacement therapy, which has been linked to a higher risk of heart disease and breast cancer.

13 Apr 2020

Fruit puree may hide flavor of dark green vegetables in commercial baby foods

Commercially prepared baby foods that purport to be loaded with dark green vegetables are sweetened with fruit puree and often don't contain a high percentage of dark green vegetable content, according to a team of researchers.

13 Apr 2020

New technique for imaging proteins in 3D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.

13 Apr 2020

Study looks into how malaria parasite evades the immune system

The parasite causing the most severe form of human malaria uses proteins to make red blood cells sticky, making it harder for the immune system to destroy it and leading to potentially fatal blood clots. New research at the Crick has identified how the parasite may control this process.

13 Apr 2020

FDA approves new Rutgers saliva test for coronavirus

The FDA has granted emergency use authorization to Rutgers' RUCDR Infinite Biologics and its collaborators for a new collection approach that utilizes saliva as the primary test biomaterial for the SARS-CoV-2 coronavirus, the first such approval granted by the federal agency.

13 Apr 2020

Large-scale proteomic analysis links glucose metabolism proteins and AD biology

In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers.

13 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

Large-scale analysis links glucose metabolism proteins to Alzheimer's disease biology

A team has identified Alzheimer's disease-specific proteins and processes that could be used for treatment targets and biomarkers.

13 Apr 2020

Cats, ferrets more vulnerable to COVID-19 than dogs

A recent Chinese study published on the preprint server BioRxiv finds that cats and ferrets appear to be extremely vulnerable to the virus, but dogs, pigs, and poultry do not seem to contract it. As preprints, papers are not yet peer-reviewed, undergoing only basic scientific screening.

12 Apr 2020

Stuttering DNA controls development of mosquito embryos

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ensure the functioning of the cell and the entire organism.

12 Apr 2020

UMSOM launches new initiative to expand COVID-19 testing

University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA, announced today the launch of a large-scale COVID-19 Testing Initiative that will significantly expand testing capability over the coming weeks, enabled by new funding of $2.5 million from the State of Maryland.

12 Apr 2020

Vaccine skeptics may process information differently than people

In 2000, the measles virus was declared eliminated from the United States. Despite cases coming in from outside the country, there were few outbreaks because most people were vaccinated against measles. And then 2019 happened.

12 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020