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Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat-;including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

Stand Up To Cancer (SU2C) today announced three Research Teams focused on bringing new therapies to clinical trials for the treatment of gastroesophageal cancer (GEC).

15 Nov 2023

World-first type 1 diabetes risk screening study in adults opens for recruitment

A world-first research programme led by the University of Bristol that will identify adults at high risk of developing type 1 diabetes opens for recruitment.

15 Nov 2023

Immune response that protects against infections also drives HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

15 Nov 2023

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

In this interview, we delve into the remarkable journey of Professor Sir Peter Barnes, a leading figure in respiratory medicine.

15 Nov 2023

Understanding asthma: The surprising influence of gut bacteria

The role of specific gut microbes in asthma.

15 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

The COVID-19 disease, due to infection with the SARS-CoV2 virus, became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life.

14 Nov 2023

Novel mechanism of maternal-fetal communication discovered

A research group from the University of Oulu, Finland, has shown that nanoparticles originating from maternal gut bacteria are present in amniotic fluid.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

The impact of broccoli sprouts and its role in resolving Crohn’s disease symptoms.

14 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide.

13 Nov 2023

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

A new study by Hospital for Special Surgery (HSS) investigators has found that an initial high-risk antibody profile for antiphospholipid syndrome (APS) tended to remain high in pediatric patients.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Vitamin D supplementation may reduce future dementia risk, study suggests

Everyone knows that vitamin D is vital for healthy bones and a stronger immune system but could low levels be a major driver of Alzheimer’s and age-related cognitive decline?

13 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

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Immune System News and Research

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

Bacteria fight phages with RNA-based immune defense

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

World-first type 1 diabetes risk screening study in adults opens for recruitment

Immune response that protects against infections also drives HIV latency

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

Understanding asthma: The surprising influence of gut bacteria

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

Novel mechanism of maternal-fetal communication discovered

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

Revolutionizing critical care: the potential of gut microbiota therapeutics

Vitamin D supplementation may reduce future dementia risk, study suggests

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Preclinical research points to a promising new treatment option for pancreatic cancer patients

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