Lungs News and Research

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Three NIH-sponsored influenza trials begin to enroll volunteers

Three clinical trials that seek to find more effective treatments for influenza are enrolling volunteers with influenza at the National Institutes of Health's Clinical Center in Bethesda, Md., and at several dozen other domestic and international sites.

6 Feb 2013

Non-coding RNA MALAT1 influences lung cancer metastasis

The vast majority - approximately 80 percent - of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied group of small RNAs, there is also a class of so-called long non-coding RNAs consisting of more than 200 nucleotides.

6 Feb 2013

Viracor-IBT Laboratories signs definitive agreement to purchase assets of Cylex

Viracor-IBT Laboratories, Inc. announced today that it has signed a definitive agreement to purchase the assets of Cylex, Inc., a global life sciences company focused on the development, manufacturing and commercialization of in vitro diagnostic products intended to illuminate immunity in the area of transplant medicine.

5 Feb 2013

UPCI researchers uncover new technique to stop growth of cancer cells

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

5 Feb 2013

Technion, Alpha Szenszor partner to commercialize lung cancer diagnostics

Alpha Szenszor Inc., a leading provider of carbon nanotube based sensors and the Technion -Israel Institute of Technology have announced a joint venture for the commercialization of advanced lung cancer diagnostics based on Volatile Organic Compound (VOC) detection from human breath.

5 Feb 2013

Gum infections may increase risk for community-acquired pneumonia

People with moderate-to-severe periodontitis are at increased risk for community-acquired pneumonia compared with those with healthy gums, show study findings.

4 Feb 2013

Risk factors for death after COPD hospitalization identified

Results from a French study suggest that a number of clinical factors may help identify patients at increased risk for death after an acute exacerbation of chronic obstructive pulmonary disease.

4 Feb 2013

COPD underdiagnosed in Chinese lung cancer patients

Chronic obstructive pulmonary disease is underdiagnosed and undertreated among lung cancer patients in China, study results show.

4 Feb 2013

Two new methods could accelerate development of improved antisense drugs

Powerful antisense drugs that target disease-associated genes to block their expression can be used to treat a broad range of diseases. Though antisense therapy has been proven effective, challenges remain in ensuring that the drugs reach their intended targets.

2 Feb 2013

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Hundreds of healthcare professionals at the Cedars-Sinai Heart Institute will wear red on Friday, Feb. 1, to mark National Wear Red Day. A few hours later, the new Cedars-Sinai Advanced Health Sciences Pavilion will be lit with a projection of the red dress symbol that represents a public education program to boost women's awareness of heart disease.

1 Feb 2013

Scientists identify specific p53 pocket that can be targeted by cancer-fighting drugs

UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year.

1 Feb 2013

Innate lymphoid cells may be new therapeutic target in treating atopic dermatitis

The increasing incidence of allergic skin diseases, and the accompanying economic burden and heightened risk of developing other allergic conditions, have spurred researchers to look for better ways to control these immune system-based disorders.

1 Feb 2013

Bioelectric signals can identify cells that are likely to develop into tumors

Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower the incidence of cancerous cells by manipulating the electrical charge across cells' membranes.

1 Feb 2013

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

The U.S. Food and Drug Administration recently announced the authorization of FerriScan R2-MRI to be marketed as an imaging companion diagnostic device for the safe and effective use of Exjade in patients with non-transfusion-dependent thalassemia.

31 Jan 2013

Cerulean initiates CRLX101 Phase 2 study in extensive-stage small cell lung cancer

Cerulean Pharma Inc., a leader in developing dynamically tumor-targeted nanopharmaceuticals, today announced that the first patient has been dosed in a randomized Phase 2 study of its lead candidate, CRLX101, in patients with extensive-stage small cell lung cancer (SCLC) sensitive to first-line platinum-based chemotherapy.

31 Jan 2013

New insight into eczema’s itch

Research shows that innate lymphoid cells accumulate in active eczema lesions and may contribute to disease progression.

31 Jan 2013

GSU associate professor receives federal grant to bolster flu vaccine research

Sang-Moo Kang, associate professor at Georgia State University's Center for Inflammation, Immunity and Infection, has received a federal five-year, $3.4 million grant to bolster research that will lead to better flu vaccines and vaccines against respiratory syncytial virus (RSV), a disease for which there is no immunization.

31 Jan 2013

Mount Sinai to initiate immunological therapy trial against chronic pulmonary sarcoidosis

Patients are currently being enrolled in the first clinical trial to investigate the efficacy of immunological therapy for chronic pulmonary sarcoidosis. The trial is being conducted by researchers at the Icahn School of Medicine at Mount Sinai.

31 Jan 2013

No proof of added benefit from aclidinium bromide in adults with COPD

The drug aclidinium bromide has been approved since October 2012 for widening the narrowed airways of adults with chronic-obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG).

31 Jan 2013

IL-13 protein could be the key to development of fibrosis in Crohn's disease

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease.

30 Jan 2013