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Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy.

3 Jul 2024

Innovative 3D printer-based test enhances early detection of Chagas disease in newborns

An innovative test that combines a DNA extraction system inspired by a modified 3D printer (PrintrLab) with loop-mediated isothermal molecular amplification (LAMP) could be used to detect T. cruzi infection -responsible for Chagas disease- in newborns.

3 Jul 2024

PVP-037: A novel imidazopyrimidine adjuvant enhancing vaccine immune responses

Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old.

3 Jul 2024

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Having higher levels of inflammation in your 20s and 30s may be linked to having memory and thinking problems at middle age, according to a study published in the July 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

Exercise boosts tumor-killing white blood cells in breast cancer patients

A new Finnish study from University of Turku shows that already a 30-minute exercise can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer patients.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Lack of affordability tops older Americans’ list of health care worries

What weighs most heavily on older adults' minds when it comes to health care?

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

Gene mutation explains heart defects in children

A new groundbreaking study sheds light on a medical question scientists have long wondered: why do 40 per cent of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain.

3 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa-;a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

2 Jul 2024

Low-dose aspirin shows promise in treating flu-related vascular inflammation during pregnancy

A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.

2 Jul 2024

Study reveals new mechanisms behind severe COVID-19 in obese individuals without diabetes

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients.

2 Jul 2024

Study links vegetable protein to delayed puberty through gut microbiome changes

A large Chinese study found that high vegetable protein intake is linked to later puberty timing and beneficial gut microbiome changes in children, while high animal protein intake is associated with earlier puberty. The gut microbiome mediates these effects.

2 Jul 2024

Study reveals refined carbs heighten inflammation and cardiovascular risk

A study in Nutrients journal finds that both the quantity and quality of carbohydrates impact inflammation and cardiovascular disease (CVD) risk. Higher refined carbohydrate intake is linked to greater inflammation and CVD, emphasizing the need for personalized dietary recommendations.

2 Jul 2024

Sedentary lifestyle and screen time linked to rising metabolic syndrome in Chinese youth

A new study reveals that sedentary behavior and increased screen time significantly contribute to the prevalence of metabolic syndrome (MetS) among Chinese children and adolescents, with 5.5% affected. Urban living, older age, and higher sedentary time increase the risk of MetS.

2 Jul 2024

MoMo study: Tracking physical fitness and activity of German youth for over 20 years

For over 20 years, the "Motorik-Modul-Studie" (MoMo) has been providing representative data on how fit and active children and young people in Germany are.

2 Jul 2024

Touch sensitivity deteriorates with age only in regions of the body with hairless skin

Like most primates, humans are remarkably touchy-feely. Starved of touch, we release more of the stress hormone cortisol, which causes the immune system to be down-regulated and the heart rate and blood pressure to go up.

2 Jul 2024

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Blood News and Research

Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Innovative 3D printer-based test enhances early detection of Chagas disease in newborns

PVP-037: A novel imidazopyrimidine adjuvant enhancing vaccine immune responses

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Exercise boosts tumor-killing white blood cells in breast cancer patients

White blood cell type identified as important contributor to inflammation in obesity

Lack of affordability tops older Americans’ list of health care worries

New hope for solid tumors with enhanced CAR-T cells

Gene mutation explains heart defects in children

New HIV test targets neglected strains in global cure hunt

Decoding the significance of subnormal liver enzyme activity

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Low-dose aspirin shows promise in treating flu-related vascular inflammation during pregnancy

Study reveals new mechanisms behind severe COVID-19 in obese individuals without diabetes

Study links vegetable protein to delayed puberty through gut microbiome changes

Study reveals refined carbs heighten inflammation and cardiovascular risk

Sedentary lifestyle and screen time linked to rising metabolic syndrome in Chinese youth

MoMo study: Tracking physical fitness and activity of German youth for over 20 years

Touch sensitivity deteriorates with age only in regions of the body with hairless skin

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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