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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

American Cancer Society awards new $792,000 grant to Yale researcher

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

4 May 2017

Researchers develop hybrid nanomaterial for destruction of cancer cells

Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective.

4 May 2017

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

A new study published in the journal Molecular Therapy reveals that HIV DNA in the genome of living animals can be removed to eliminate further infection. While a permanent cure for infection caused by HIV remains a challenge due to the ability of the virus to hide away in latent reservoirs. The study team comprising Wenhui Hu, Kamel Khalili, Laura H. Carnell, and Won-Bin Young carried out an experiment on three different animal models.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Chromatrap introduces new FFPE ChIP-seq assay kit for tissue samples, biopsies, and difficult to lyse samples

Chromatrap has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded tissue.

From Chromatrap® - Porvair Sciences Ltd 4 May 2017

New and improved solid phase ChIP assay kit for FFPE tissues introduced by Chromatrap

Chromatrap® has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation (ChIP) assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded (FFPE) tissue.

From Chromatrap® - Porvair Sciences Ltd 4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Phthalate exposure linked to increased risk of allergies among children

Phthalates, which are used as plasticizers in plastics, can considerably increase the risk of allergies among children.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

New research begins at University of Warwick to understand cause of brain tumors

A team based at the University's Warwick Medical School will study brain tumor cells in the lab to understand more about the cell division process, and how it can cause cancer when it goes wrong.

2 May 2017

Bacteria can mutate at different speeds to survive under difficult circumstances, study shows

Bacteria need mutations -- changes in their DNA code -- to survive under difficult circumstances. When necessary, they can even mutate at different speeds.

2 May 2017

Researchers create new tool that reveals insights into cellular development

Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. Rooted in the mathematical field of topology, the tool provides a roadmap that offers detailed insight into how stem cells give rise to specialized cells.

2 May 2017

Researchers uncover molecule that may explain smoking-CHD connection

Cigarette smoking accounts for about one-fifth of cases of coronary heart disease, one of the leading causes of death worldwide, but precisely how smoking leads to CHD has long been unclear.

2 May 2017

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

Surgery and radiation remove, kill, or damage cancer cells in a certain area. But chemotherapy -- which uses medicines or drugs to treat cancer -- can work throughout the whole body, killing cancer cells that have spread far from the original tumor.

2 May 2017

New chiral molecular sieves may lead to production of better drugs

An international team of researchers, led by Mark E. Davis at Caltech, has succeeded in making the first chiral molecular sieves. This discovery opens new areas of investigation in both chemistry and biology, and has broad implications for pharmaceutical companies and other specialized chemical manufacturers.

2 May 2017

DNA News and Research

Further Reading

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

American Cancer Society awards new $792,000 grant to Yale researcher

Researchers develop hybrid nanomaterial for destruction of cancer cells

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

Chromatrap introduces new FFPE ChIP-seq assay kit for tissue samples, biopsies, and difficult to lyse samples

New and improved solid phase ChIP assay kit for FFPE tissues introduced by Chromatrap

Lethal DNA re-replication may be used to attack cancer cells

New research uncovers role of mysterious molecule in skin cancer

Phthalate exposure linked to increased risk of allergies among children

Researchers identify key player in initiation and progression of melanoma

Scientists map genetic changes that help drive aggressive brain tumor

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

New research begins at University of Warwick to understand cause of brain tumors

Bacteria can mutate at different speeds to survive under difficult circumstances, study shows

Researchers create new tool that reveals insights into cellular development

Researchers uncover molecule that may explain smoking-CHD connection

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

New chiral molecular sieves may lead to production of better drugs

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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