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Novel inhibitor to fight metastatic prostate cancer shows promise

When prostate cancer spreads it is often a deadly disease, but now a Stony Brook University-led research team believes a new approach that inhibits a specific fatty acid binding protein (FABP) may be the key to halting disease progression.

30 Jan 2020

Group A streptococcus strains that are less susceptible to commonly used antibiotics identified

Infectious disease scientists identified strains of group A streptococcus that are less susceptible to commonly used antibiotics, a sign that the germ causing strep throat and flesh-eating disease may be moving closer to resistance to penicillin and other related antibiotics known as beta-lactams.

30 Jan 2020

Researchers examine abnormal neuron activity in Rett syndrome

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and key developmental periods pass, the brain becomes less malleable--but certain experiences create opportunities for parts of the adult brain to rewire and learn again.

29 Jan 2020

Study: 25% of pathogenic bacteria can spread antibiotic resistance directly to peers

Biomedical engineers at Duke University have demonstrated that at least 25 percent of antibiotic-resistant pathogenic bacteria found in clinical settings are capable of spreading their resistance directly to other bacteria.

29 Jan 2020

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Claudio Franceschi, a world-renowned scientist, professor at the University of Bologna (Italy) and head of the Research Laboratory for Systems Medicine of Healthy Aging at Lobachevsky University, together with other members of an international research team, has described the mechanisms underlying chronic inflammation and identified several risk factors leading to disease.

29 Jan 2020

Study reveals how the gut's protective mechanisms ramp up with food intake

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

29 Jan 2020

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

The study reveals a detailed epigenetic mechanism for how interleukin-1-beta, a common cytokine that helps fight infections during inflammation, plays a critical role in cancer metastasis.

29 Jan 2020

New strategy using organoids to study childhood brain tumors

A new study reports the creation of in vitro models of brain tumors in children using organoids derived from stem cells, which will help to screen new drugs for efficacy and thus improve the rate of drug development. The study, titled 'Modeling medulloblastoma in vivo and with human cerebellar organoids,' is published in the journal Nature Communications.

29 Jan 2020

H.E.L Group appoints three new members to strengthen production and service support

H.E.L Group, a global manufacturer of innovative laboratory tools for process optimization, safety and scale-up, today announced the appointment of three new members to its senior team, who will focus primarily on strengthening production and service support for its scientific instrumentation and software.

From Zyme Communications Ltd 29 Jan 2020

Researchers develop new strategy to study childhood brain tumors

Researchers are at work to find effective treatments to help young patients with brain tumors. Hundreds of brain organoids have been developed in the laboratories of the University of Trento to understand the genetic mechanisms responsible for these hard to treat diseases.

29 Jan 2020

Study identifies previously unknown toxic by-products potentially present in drinking water

Researchers at John Hopkins University have found that the most common method for disinfecting water can generate toxic by-products.

29 Jan 2020

Study advances the understanding of capillary regression

Many diseases arise from abnormalities in our capillaries, tiny exquisitely branching blood vessel networks that play a critical role in tissue health.

29 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

Analysis of Postmortem Microbes using Gas Chromatography

In this interview, Katelynn Perrault, from Chaminade University of Honolulu talks to News-Medical and Life Sciences about her research into using Multidimensional Gas Chromatography to achieve odor profiling of postmortem microbes.

From Pittcon 29 Jan 2020

Benchling launches new solution to help life science companies maximize lab automation investments

Benchling, the leading life sciences R&D cloud platform, today announced the launch of Benchling for Lab Automation, a new solution to help life sciences companies maximize lab automation investments.

From Society for Laboratory Automation and Screening (SLAS2020) 28 Jan 2020

Coronavirus spreads - Australian breakthrough

Novel coronavirus, temporarily named “2019-nCoV”, has affected over 4,600 persons across the world and is spreading at a rapid pace say experts. The World Health Organization and other health organizations have stepped up vigilance to detect and isolate the infection to contain outbreaks.

28 Jan 2020

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children's) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic Granulomatosis (X-CGD), a rare and severe immune dysfunction. Six of them are free of treatment for complications generated by the disease.

28 Jan 2020

Laboratory News and Research

Novel inhibitor to fight metastatic prostate cancer shows promise

Group A streptococcus strains that are less susceptible to commonly used antibiotics identified

Researchers examine abnormal neuron activity in Rett syndrome

Study: 25% of pathogenic bacteria can spread antibiotic resistance directly to peers

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Study reveals how the gut's protective mechanisms ramp up with food intake

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

New strategy using organoids to study childhood brain tumors

H.E.L Group appoints three new members to strengthen production and service support

Researchers develop new strategy to study childhood brain tumors

Study identifies previously unknown toxic by-products potentially present in drinking water

Study advances the understanding of capillary regression

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Analysis of Postmortem Microbes using Gas Chromatography

Benchling launches new solution to help life science companies maximize lab automation investments

Coronavirus spreads - Australian breakthrough

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

NIU professor gets $372,500 to study link between brain health and exercise

Chan Zuckerberg Initiative announces over $1.3 million to support Global BioImaging

Non-invasive electrostimulation of the vagus nerve improves memory in mice

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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