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Study reveals novel therapeutic targets for airway relaxation

Bronchial constriction is what makes many lung diseases like asthma so dangerous. Researchers have discovered a new signaling pathway that causes the airways to widen.

17 Nov 2022

MGI announces European launch of new MGISP-Smart 8 automated sample preparation system and empowerment program at MEDICA to further access to genomics

MGI, a company committed to building core tools and technology to lead life science, today announced the introduction of the latest MGISP-Smart 8 automated sample preparation system to Europe and the first iteration of its Empowerment Program at the MEDICA Trade Fair, taking place November 14-17 in Düsseldorf.

From MGI 17 Nov 2022

Experts investigate the role of IL-26 in COVID-19

Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory response that signifies severe cases of the disease. The findings, which are presented in Frontiers in Immunology, indicate that IL-26 is a potential biomarker for severe COVID-19.

17 Nov 2022

Study analyzes left digit bias in organ donors entering a new decade of age

American transplant centers as well as organ procurement organizations, the groups responsible for recovering organs from deceased donors in the United States, were less likely to accept or select organs from donors who were 70 years old when they died compared to those who were 69, new research found.

17 Nov 2022

Experts highlight the need to study and develop treatments for fungal infections

Fungi in the soil cause a significant number of serious lung infections in 48 out of 50 states and the District of Columbia, including many areas long thought to be free of deadly environmental fungi, according to a study by researchers at Washington University School of Medicine in St. Louis.

17 Nov 2022

National Institutes of Health funds a five-year, $11 million initiative

The conversations between our bone and muscle change as we age, and both are the weaker for it, Medical College of Georgia scientists say.

17 Nov 2022

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues unharmed. Scientists have dubbed this type of targeted approach a "prodrug" -; a medicine designed to release its payload in a particular area of the body and in no other areas.

17 Nov 2022

Research highlights an understudied aspect of Alzheimer’s disease

Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain -; the memory area -; before spreading to parts of the brain important for thinking and planning.

17 Nov 2022

Study finds a lower compliance rate with recently released guidelines for COVID-19 care

Uptake of national guidelines for the treatment of children hospitalized with COVID-19 fell well below what would typically be expected, report researchers at the Medical University of South Carolina (MUSC) and elsewhere in Pediatrics.

17 Nov 2022

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

17 Nov 2022

Study reveals neglected or late TB diagnoses related to COVID-19

In a recent study published in the journal BMJ Medicine, researchers modeled changing patterns in sex- and age-stratified new and relapse tuberculosis (TB) case notifications reported to the World Health Organization (WHO) for 45 nations with high TB, TB/human immunodeficiency virus (HIV) and multidrug-resistant TB (MDR-TB) burden between 2013 and 2019 due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

16 Nov 2022

NYU Langone Health receives "A"s for patient safety from Leapfrog

NYU Langone Health has once again received "A"s for patient safety, with Tisch Hospital, Kimmel Pavilion, NYU Langone Hospital—Brooklyn, and NYU Langone Hospital—Long Island each earning the top grade in the fall 2022 Leapfrog Hospital Safety Grade.

16 Nov 2022

Modified CEUS criteria using perfluorobutane can help diagnose high-risk hepatocellular carcinoma

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), diagnostic performance of LR-5 for hepatocellular carcinoma (HCC) diagnosis was not significantly different between modified contrast-enhanced ultrasound (CEUS) using perfluorobutane and CT/MRI LI-RADS version 2018.

16 Nov 2022

Researchers discover the mechanism for heart complications from immune checkpoint inhibitors

Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors.

16 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Clostridioides difficile, often referred to as C. difficile or C. diff, is a bacterium that causes severe intestinal illness and, as its name suggests, can be difficult to study and treat.

16 Nov 2022

Machine learning algorithm predicts a tumor’s response to immune checkpoint blockade

Predicting which patients will respond well to treatment is a quandary that has plagued the field of cancer immunotherapy for more than four decades.

16 Nov 2022

Weak evidence that programs to mitigate housing insecurity lead to positive health outcomes

Research finds low-certainty evidence that programs such as emergency rent assistance, legal assistance with waitlist priority for public housing, long-term rent subsidies and homeownership assistance lead to positive health outcomes.

16 Nov 2022

Stress from fears about Covid-19 led to anxiety and depressive symptoms in pregnant women

A study that assessed stress, anxiety and depressive symptoms in pregnant women from seven Western countries during the first major wave of the Covid-19 pandemic (April 17 to May 31, 2020) shows that stress from fears about Covid-19 led to anxiety and depressive symptoms above normal levels.

16 Nov 2022

Study describes risk factors for people with chronic pancreatitis to develop diabetes

A new study by Cedars-Sinai investigators describes risk factors that could make it more likely for people who have chronic pancreatitis, an ongoing inflammation of the pancreas, to develop diabetes. The findings are published in Diabetes Care.

16 Nov 2022

Medicine News and Research

Study reveals novel therapeutic targets for airway relaxation

MGI announces European launch of new MGISP-Smart 8 automated sample preparation system and empowerment program at MEDICA to further access to genomics

Experts investigate the role of IL-26 in COVID-19

Study analyzes left digit bias in organ donors entering a new decade of age

Experts highlight the need to study and develop treatments for fungal infections

National Institutes of Health funds a five-year, $11 million initiative

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Research highlights an understudied aspect of Alzheimer’s disease

Study finds a lower compliance rate with recently released guidelines for COVID-19 care

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

Study reveals neglected or late TB diagnoses related to COVID-19

NYU Langone Health receives "A"s for patient safety from Leapfrog

Modified CEUS criteria using perfluorobutane can help diagnose high-risk hepatocellular carcinoma

Researchers discover the mechanism for heart complications from immune checkpoint inhibitors

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Machine learning algorithm predicts a tumor’s response to immune checkpoint blockade

Weak evidence that programs to mitigate housing insecurity lead to positive health outcomes

Stress from fears about Covid-19 led to anxiety and depressive symptoms in pregnant women

Study describes risk factors for people with chronic pancreatitis to develop diabetes

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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