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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

QIAGEN announces commercialization of AdnaTest kit for clinical research in prostate cancer

QIAGEN N.V. today announced it is commercializing the Research use only AdnaTest Prostate Cancer Panel AR-V7 to detect the androgen receptor splice variant 7 (AR-V7) from liquid biopsies to investigate resistance to potential drugs for advanced prostate cancer.

From QIAGEN Manchester Limited 31 Mar 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

Fighting colorectal cancer

Colorectal cancer is a combined term to describe the malignant tumors that occur in the large intestine; the colon being the upper part of the large intestine and the rectum being the lowest part of the large intestine.

31 Mar 2017

Scientists uncover how tumor cells can switch disguises to spread easily around the body

Scientists have uncovered how tumor cells in aggressive uterine cancer can switch disguises and spread so quickly to other parts of the body.

30 Mar 2017

Combining anticancer drug with antirheumatic produces improved effects against tumors

Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy.

30 Mar 2017

Study identifies specific genetic risk factors that increase susceptibility to gliomas

A massive new study involving blood samples from over 30,000 individuals has identified 13 new genetic risk factors for glioma, the most common type of malignant brain tumor in adults

29 Mar 2017

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

Nearly 50 years into the "war" on cancer, doctors possess weapons that once would have seemed magical in their tumor-killing specificity.

29 Mar 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

Study identifies protein as potential therapeutic target for pancreatic cancer

A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five-year survival rate.

28 Mar 2017

Liquid biopsies that enable screening, early detection of cancer attract attention of investors

Interest is high in the development of blood-based tests that can be used to screen individuals for cancer. That isn't new, liquid biopsy industry has attracted attention and investment for the past few years.

28 Mar 2017

Breakthrough technique harvests stem cells from urine to study Down syndrome

One of the biggest challenges in studying Down syndrome is finding the right research model. Animals and established cell lines are limited in their ability to mimic human disease, and results don't always translate to patient populations.

28 Mar 2017

Blood-sucking flies can act as 'flying syringes' to track emergence of new diseases

Blood-sucking flies can act as 'flying syringes' to detect emerging infectious diseases in wild animals before they spread to humans, according to research published in the journal eLife.

28 Mar 2017

Rogue proteins involved in breast cancer point to potential treatment options

For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies.

28 Mar 2017

Researchers develop two-pronged approach to personalize breast cancer treatment

The goal of cancer therapy is to destroy the tumor or stop it from growing and spreading to other parts of the body.

28 Mar 2017

High concentrations of stress hormone affect DNA processes and mental health

High concentrations of the stress hormone, Cortisol, in the body affect important DNA processes and increase the risk of long-term psychological consequences.

28 Mar 2017

Proteomics unravels molecular mechanisms influenced by genetic variations

How does type 2 diabetes develop? A team of researchers headed by the Helmholtz Zentrum München and the Technical University of Munich has come closer to finding an answer to this problem. The team examined the functional effects of exemplary genetic variations relevant for type 2 diabetes. Their approach can be applied to many clinical pictures.

28 Mar 2017

MIT researchers develop new technique for early liver cancer diagnosis

In many parts of the world, including Southeast Asia and sub-Saharan Africa, exposure to a fungal product called aflatoxin is believed to cause up to 80 percent of liver cancer cases. This fungus is often found in corn, peanuts, and other crops that are dietary staples in those regions.

28 Mar 2017

Kent state researchers use DNA origami to create ‘nano cage’ for deeper study of cancer cell growth

According to the American Cancer Society, there will be an estimated 1,688,780 new cancer cases diagnosed and 600,920 cancer deaths in the U.S. in 2017.

28 Mar 2017

Scientists show p300 protein may stop MDS from developing into leukemia

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that p300, a protein that increases gene expression by attaching acetyl molecules to DNA, may stop myelodysplastic syndrome (MDS) from developing into acute myeloid leukemia (AML). The study was published in the journal Leukemia.

27 Mar 2017

Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

27 Mar 2017

DNA News and Research

Further Reading

QIAGEN announces commercialization of AdnaTest kit for clinical research in prostate cancer

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Fighting colorectal cancer

Scientists uncover how tumor cells can switch disguises to spread easily around the body

Combining anticancer drug with antirheumatic produces improved effects against tumors

Study identifies specific genetic risk factors that increase susceptibility to gliomas

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

TSRI researchers reveal how viruses incapacitate bacterial defense system

Study identifies protein as potential therapeutic target for pancreatic cancer

Liquid biopsies that enable screening, early detection of cancer attract attention of investors

Breakthrough technique harvests stem cells from urine to study Down syndrome

Blood-sucking flies can act as 'flying syringes' to track emergence of new diseases

Rogue proteins involved in breast cancer point to potential treatment options

Researchers develop two-pronged approach to personalize breast cancer treatment

High concentrations of stress hormone affect DNA processes and mental health

Proteomics unravels molecular mechanisms influenced by genetic variations

MIT researchers develop new technique for early liver cancer diagnosis

Kent state researchers use DNA origami to create ‘nano cage’ for deeper study of cancer cell growth

Scientists show p300 protein may stop MDS from developing into leukemia

Study shows how epigenetic randomness helps cancer cells proliferate

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