Lungs News and Research

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Four-point plan to improve palliative care discussions

In an editorial appearing in the October 25 issue of The New England Journal of Medicine, medical oncologists at Johns Hopkins and Brigham and Women's hospitals provide a four-point plan for integrating palliative care discussions throughout the treatment of patients with terminal illnesses.

25 Oct 2012

CINJ makes experts available during National Lung Cancer Awareness Month

According to the American Cancer Society, nearly 6,000 new cases of lung cancer are expected to be diagnosed in New Jersey this year, and 4,200 people will die from the disease.

25 Oct 2012

Vascular endothelial cells play a larger role in pulmonary hypertension

It turns out the muscle cells on the outside of blood vessels have been wrongly accused for instigating lung disease. New research shows that while these muscle cells are responsible for constricting or dilating the blood vessels, they are not responsible for sensing the amount of oxygen that gets to the lungs. That message comes from the endothelial cells - special cells that line the blood vessels - along a "signalling pathway."

25 Oct 2012

Scientists unravel physical properties of lung mucus

Mucus coats our airways' internal surfaces. The viscous gel humidifies the lungs and prevents viruses and other small particles like diesel soot from entering the body unchecked. Previously unclear was the extent to which such nanoparticles are able to move through the lungs' mucus. Here, the research evidence was contradictory. Scientists could not explain why, in inhaled medication development, drug nanoparticles often simply got stuck in the mucus never making it to their target destination inside the lung cells.

25 Oct 2012

12-chemokine gene signature can predict presence of lymph node-like structures in MM

Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these immune structures, the researchers said, appears to be associated with better survival and may indicate the possibility of selecting patients for immunotherapy based solely on the immune-related makeup of their tumors as an approach to personalized medicine.

25 Oct 2012

Paper details new target for anti-cancer drug development

In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ends of our DNA.

25 Oct 2012

Patients without lung injury may benefit from mechanical ventilation with lower tidal volume use

Among patients without acute respiratory distress syndrome, protective mechanical ventilation with use of lower tidal volumes (the volume of air inhaled and exhaled during each breath) was associated with better outcomes including less lung injury, lower mortality, fewer pulmonary infections and a shorter hospital length of stay, according to a meta-analysis of previous studies, reported in the October 24/31 issue of JAMA.

25 Oct 2012

U.S. Marshals seize dietary supplements and unapproved drugs from Confidence

At the request of the U.S. Food and Drug Administration, U.S. Marshals recently seized dietary supplements and unapproved drugs from Confidence, Inc., of Port Washington, N.Y.

24 Oct 2012

Up to 10% of acute lung injuries may be drug-related

A population-based study has found that drug-induced acute lung injury accounts for around 9.5% of all acute lung injury cases.

23 Oct 2012

Vascular cell generation could be used to treat vascular disorders

A study in mice has shown that large numbers of vascular endothelial cells can be generated from human amniotic fluid-derived cells.

23 Oct 2012

X-ray technology improves early detection of pulmonary disease

Chronic obstructive pulmonary disease (COPD) is considered the fourth most common cause of death in the United States. Usually the precursor to this life-threatening lung disease is a chronic bronchitis. Partially destroyed alveoli and an over-inflation of the lungs, known as emphysema, are serious side effects. However, the subtle differences in the tissue are barely discernable in standard X-ray images.

23 Oct 2012

Computed tomography aids scleroderma lung disease prognosis

High-resolution computed tomography is useful for the prognosis of patients with systemic scleroderma-related interstitial lung disease, research shows.

22 Oct 2012

Medicare's policy on compounded drugs under scrutiny; Lawsuits growing in meningitis outbreak

The Associated Press reports on the role Medicare plays in national drug purchasing and The Washington Post finds the "race is on" to sign up clients for lawsuits.

22 Oct 2012

First Edition: October 22, 2012

Today's headlines include the latest news about how health policies are playing on the campaign trail as candidates move into the home stretch.

22 Oct 2012

Short-term secondhand smoke exposure can lead to airway restriction

Heavy concentrations of secondhand smoke, such as those found in smoke-filled bars and cars, can lead to airway restriction for bystanders within minutes of exposure. The study, presented at CHEST 2012, the annual meeting of the American College of Chest Physicians, showed that after 20 minutes of exposure to highly concentrated secondhand smoke, participants experienced near immediate physiologic changes, including airway resistance and impedance.

22 Oct 2012

Chinese herbs may show significant benefits for patients with NSCLC, IPF and influenza

Chinese herbs, including JHQG, BFXL, and BFHX, may show significant benefits for patients with non-small cell lung cancer (NSCLC), idiopathic pulmonary fibrosis (IPF), and influenza.

22 Oct 2012

Cough, difficulty breathing and chest pain key symptoms of pulmonary embolism

Difficulty breathing, chest pain, and cough may sound like symptoms of a heart attack; however, new research shows that these are the key symptoms for pulmonary embolism (PE), a potentially fatal blockage in the lung.

22 Oct 2012

Fungal exposure in homes could increase risk of sarcoidosis

People who are exposed to mold in their homes could be at an increased risk for sarcoidosis, a chronic inflammatory lung disease. Researchers from Sweden and Slovenia tested 62 nonsmoking patients with sarcoidosis, 34 of whom had extrapulmonary manifestations (EPM).

22 Oct 2012

Statin use may improve overall survival and reduce risk of recurrence in resected NSCLC patients

Patients who have undergone resection for non-small cell lung cancer (NSCLC) may improve their overall survival and reduce the risk of recurrence by taking statins.

22 Oct 2012