Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

COVID-19 and blood group in aortic valve replacement

The COVID-19 pandemic has been found to cause disproportionate harm in patients with cardiovascular disease, especially among the elderly population, among other risk factors. However, a new study published on the preprint server medRxiv* in June 2020 is the first to report its clinical features in patients with aortic stenosis who have had a transcatheter aortic valve replacement (TAVR).

18 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

Globally, 350 million could be at risk of severe COVID-19 and hospitalization

Now, a new study shows that one in five individuals is at risk of getting a severe case of COVID-19 due to the presence of underlying disease. The study appeared in the latest issue of The Lancet Global Health this week.

17 Jun 2020

Low potassium levels in COVID-19 disease

Now a new study by an Italian team of researchers published in June 2020 on the preprint server medRxiv reports that potassium levels are often low in COVID-19 disease, mostly due to the urinary loss of potassium.

17 Jun 2020

Study: Nearly 10% of patients continue to use opioids more than 90 days after heart surgery

Nearly 10 percent of patients who are prescribed opioid medications following heart surgery will continue to use opioids more than 90 days after the procedure, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

17 Jun 2020

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Researchers at Radboud University Medical Center in the Netherlands reported an increase of heparanase activity and heparan sulfate levels in the plasma of patients with coronavirus disease (COVID-19), which was also associated with the severity of the condition – suggesting, in turn, potential treatment utility of low molecular weight heparins. The paper is currently available on the medRxiv* preprint server.

16 Jun 2020

Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Cascade Chemistry, a leading contract research and manufacturing organization serving the pharmaceutical, materials, and chemical industries, today announced that it has been selected to produce the active pharmaceutical ingredient for clinical trial supplies of RBT-9, an investigational therapy entering a Phase 2 trial for the treatment of COVID-19 patients who are at high risk of deteriorating health due to age or comorbid conditions such as kidney or cardiovascular disease.

16 Jun 2020

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Scientists have discovered an important cell signaling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.

16 Jun 2020

Breakthrough drug significantly delays onset of type 1 diabetes, study finds

Emily Sims, M.D. today shared new findings that a breakthrough drug significantly delays the onset of type 1 diabetes (T1D).

15 Jun 2020

NIH launches a centralized, secure enclave to store and study COVID-19 patient data

The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country.

15 Jun 2020

Vitamin K may offer protective health benefits as we age, study suggests

A new, multi-ethnic study found older adults with low vitamin K levels were more likely to die within 13 years compared to those whose vitamin K levels were adequate.

15 Jun 2020

A teen’s death from COVID

It started as a normal day. Dawn Guest, 54, got up and headed out to her job as a nurse around 5 a.m. She heard her 16-year-old son, Andre, stirring in his room, but he had always been an earlier riser, even when his school was shut for COVID-19.

15 Jun 2020

COVID-19 may trigger the onset of diabetes in healthy people

Emerging evidence suggests that COVID-19 may actually trigger the onset of diabetes in healthy people and also cause severe complications of pre-existing diabetes.

12 Jun 2020

COVID-19 poses a global threat to the entire nervous system

A new review of neurological symptoms of COVID-19 patients in current scientific literature reveals the disease poses a global threat to the entire nervous system, reports a Northwestern Medicine study published this week in Annals of Neurology.

11 Jun 2020

Strength training increases muscle strength and size in patients with cirrhosis

Three hours of weekly strength training combined with protein supplements leads to both bigger and stronger muscles in patients with cirrhosis. This is shown by a new study from Aarhus University and Aarhus University Hospital.

11 Jun 2020

$People with diabetes have increased risk for bone fractures$

People with diabetes have increased risk for bone fractures

People living with diabetes are at greater risk of bone fractures, new research led by the University of Sheffield has found.

11 Jun 2020

Scientists develop new test to help identify people at risk for developing liver cancer

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient's previous exposure to certain viruses.

11 Jun 2020

A family with five doctors — and two COVID deaths

On the morning of April 1, Dr. Priya Khanna inched her way from the bedroom to the front door, using walls, doors and railings to hold herself up long enough to get to the stretcher waiting outside. She had been battling COVID-19 for five days and was struggling to breathe.

11 Jun 2020

Co-existing non-communicable diseases linked to higher risk of illness and death from COVID-19

The interaction of COVID-19 with co-existing non-communicable diseases (NCDs) is a perfect storm, particularly for communities of poverty, according to a new opinion piece published by Columbia Mailman School of Public Health researchers in the journal British Medical Journal.

11 Jun 2020

Hyperprogression to immune blockade followed by a response with cabozantinib in metastatic RCC

Volume 11, Issue 22 of @Oncotarget reported that more and more patients receive first-line treatment with immunotherapy combinations and not all patients respond in metastatic renal cell carcinoma.

10 Jun 2020

Nephrology News and Research

Further Reading

COVID-19 and blood group in aortic valve replacement

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Globally, 350 million could be at risk of severe COVID-19 and hospitalization

Low potassium levels in COVID-19 disease

Study: Nearly 10% of patients continue to use opioids more than 90 days after heart surgery

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Breakthrough drug significantly delays onset of type 1 diabetes, study finds

NIH launches a centralized, secure enclave to store and study COVID-19 patient data

Vitamin K may offer protective health benefits as we age, study suggests

A teen’s death from COVID

COVID-19 may trigger the onset of diabetes in healthy people

COVID-19 poses a global threat to the entire nervous system

Strength training increases muscle strength and size in patients with cirrhosis

People with diabetes have increased risk for bone fractures

Scientists develop new test to help identify people at risk for developing liver cancer

A family with five doctors — and two COVID deaths

Co-existing non-communicable diseases linked to higher risk of illness and death from COVID-19

Hyperprogression to immune blockade followed by a response with cabozantinib in metastatic RCC

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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